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  1. Deep inspiration (DI) has been shown to induce bronchodilation and bronchoprotection in bronchochallenged healthy subjects, but not in asthmatics. Strain-induced relaxation of airway smooth muscle (ASM) is con...

    Authors: Yuto Yasuda, Lu Wang, Pasquale Chitano and Chun Y. Seow
    Citation: Respiratory Research 2023 24:250
  2. Platelet count (PLT) is associated positively with lung cancer risk but has a more complex association with body mass index (BMI), positive only in women (mainly never smokers) and inverse in men (mainly ever ...

    Authors: Sofia Christakoudi, Konstantinos K. Tsilidis, Evangelos Evangelou and Elio Riboli
    Citation: Respiratory Research 2023 24:249
  3. Microbiome dysbiosis can have long-lasting effects on our health and induce the development of various diseases. Bronchopulmonary dysplasia (BPD) is a multifactorial disease with pre- and postnatal origins inc...

    Authors: Birte Staude, Silvia Gschwendtner, Tina Frodermann, Frank Oehmke, Thomas Kohl, Susanne Kublik, Michael Schloter and Harald Ehrhardt
    Citation: Respiratory Research 2023 24:248
  4. The dysregulation of local circadian clock has been implicated in the pathogenesis of a broad spectrum of diseases. However, the pathophysiological role of intrinsic circadian clocks Rev-Erbα in ischemia-reper...

    Authors: Shi-Jye Chu, Wen-I Liao, Hsin-Ping Pao, Shu-Yu Wu and Shih-En Tang
    Citation: Respiratory Research 2023 24:247
  5. Although COVID-19 vaccines and their booster regimens protect against symptomatic infections and severe outcomes, there is limited evidence about their protection against asymptomatic and symptomatic infection...

    Authors: Ting Zeng, Yaoqin Lu, Yanji Zhao, Zihao Guo, Shengzhi Sun, Zhidong Teng, Maozai Tian, Jun Wang, Shulin Li, Xucheng Fan, Weiming Wang, Yongli Cai, Gengze Liao, Xiao Liang, Daihai He, Kai Wang…
    Citation: Respiratory Research 2023 24:246
  6. Interstitial lung abnormalities (ILA) often represent early fibrotic changes that can portend a progressive fibrotic phenotype. In particular, the fibrotic subtype of ILA is associated with increased mortality...

    Authors: Aravind A. Menon, Minyi Lee, Xu Ke, Rachel K. Putman, Takuya Hino, Jonathan A. Rose, Fenghai Duan, Samuel Y. Ash, Michael H. Cho, George T. O’Connor, Josée Dupuis, Hiroto Hatabu, Marc E. Lenburg, Ehab S. Billatos and Gary M. Hunninghake
    Citation: Respiratory Research 2023 24:245
  7. This study, in patients with symptomatic chronic obstructive pulmonary disease (COPD), explored switching therapy from non-extrafine high-dose inhaled corticosteroid/long-acting β2-agonist (ICS/LABA; fluticasone ...

    Authors: Gwen S. Skloot, Alessandro Guasconi, Benjamin R. Lavon, George Georges, Wilfried De Backer, Dmitry Galkin, Mauro Cortellini, Ilaria Panni and Jason H. T. Bates
    Citation: Respiratory Research 2023 24:244
  8. Chronic obstructive pulmonary disease (COPD) is a lung disease characterised by airflow-limiting inflammation and mucus production. Acute exacerbations are a major cause of COPD-related morbidity and mortality...

    Authors: Cecilia Brettoni, Alessandro Muzzi, Simona Rondini, Vincent Weynants and Silvia Rossi Paccani
    Citation: Respiratory Research 2023 24:243
  9. The pulmonary extracellular matrix (ECM) is a macromolecular structure that provides mechanical support, stability and elastic recoil for different pulmonary cells including the lung fibroblasts. The ECM plays...

    Authors: Sakshi Phogat, Fama Thiam, Safiya Al Yazeedi, Filsan Ahmed Abokor and Emmanuel Twumasi Osei
    Citation: Respiratory Research 2023 24:242
  10. Computed tomography (CT) imaging and artificial intelligence (AI)-based analyses have aided in the diagnosis and prediction of the severity of COVID-19. However, the potential of AI-based CT quantification of ...

    Authors: Hiromu Tanaka, Tomoki Maetani, Shotaro Chubachi, Naoya Tanabe, Yusuke Shiraishi, Takanori Asakura, Ho Namkoong, Takashi Shimada, Shuhei Azekawa, Shiro Otake, Kensuke Nakagawara, Takahiro Fukushima, Mayuko Watase, Hideki Terai, Mamoru Sasaki, Soichiro Ueda…
    Citation: Respiratory Research 2023 24:241
  11. Idiopathic pulmonary fibrosis (IPF) has an unknown aetiology and limited treatment options. A recent meta-analysis identified three novel causal variants in the TERT, SPDL1, and KIF15 genes. This observational st...

    Authors: Maria Hollmén, Atte Laaka, Juulia J. Partanen, Jukka Koskela, Eva Sutinen, Riitta Kaarteenaho, Mari Ainola and Marjukka Myllärniemi
    Citation: Respiratory Research 2023 24:240
  12. Use of combinations of long-acting β2 agonists/long-acting muscarinic antagonists (LABA/LAMA) in patients with chronic obstructive pulmonary disease (COPD) is increasing. Nevertheless, existing evidence on cardio...

    Authors: Chun-Yu Chen, Sheng-Wei Pan, Chia-Chen Hsu, Jason J. Liu, Hiraku Kumamaru and Yaa-Hui Dong
    Citation: Respiratory Research 2023 24:239
  13. Rhinovirus infections commonly evoke asthma exacerbations in children and adults. Recurrent asthma exacerbations are associated with injury-repair responses in the airways that collectively contribute to airwa...

    Authors: Cassandra Spector, Camden M. De Sanctis, Reynold A. Panettieri Jr. and Cynthia J. Koziol-White
    Citation: Respiratory Research 2023 24:238
  14. Airway basal stem cells (ABSCs) have self-renewal and differentiation abilities. Although an abnormal mechanical environment related to chronic airway disease (CAD) can cause ABSC dysfunction, it remains uncle...

    Authors: Li-Qin Lin, Hai-Kang Zeng, Yu-Long Luo, Di-Fei Chen, Xiao-Qian Ma, Huan-Jie Chen, Xin-Yu Song, Hong-Kai Wu and Shi-Yue Li
    Citation: Respiratory Research 2023 24:237
  15. The role of the immune system in the pathobiology of Idiopathic Pulmonary Fibrosis (IPF) is controversial.

    Authors: Tamara Cruz, Núria Mendoza, Sandra Casas-Recasens, Guillaume Noell, Fernanda Hernandez-Gonzalez, Alejandro Frino-Garcia, Xavi Alsina-Restoy, María Molina, Mauricio Rojas, Alvar Agustí, Jacobo Sellares and Rosa Faner
    Citation: Respiratory Research 2023 24:236
  16. The ORBE II study aimed to describe the characteristics and clinical outcomes of adult patients with severe eosinophilic asthma (SEA) treated with benralizumab in a real-world setting in Spain.

    Authors: Alicia Padilla-Galo, Isabel Moya Carmona, Pilar Ausín, Luis Carazo Fernández, Ismael García-Moguel, José Luis Velasco-Garrido, Rubén Andújar-Espinosa, Francisco Casas-Maldonado, Eva Martínez-Moragón, Carlos Martínez Rivera, Elisabet Vera Solsona, Fernando Sánchez-Toril López, Andrea Trisán Alonso, Marina Blanco Aparicio, Marcela Valverde-Monge, Borja Valencia Azcona…
    Citation: Respiratory Research 2023 24:235
  17. As the prevalence of OSA increases in older patients, the proportion of elderly patients treated with CPAP is expected to become even higher. We studied CPAP-adherence in a real-life cohort involving a large p...

    Authors: Arnaud Prigent, Clément Blanloeil, Anne-Laure Serandour, Franck Barlet, Frédéric Gagnadoux and Dany Jaffuel
    Citation: Respiratory Research 2023 24:234
  18. Bone marrow mesenchymal stem cell-derived extracellular vesicles (BMSC-EVs) have been highly studied with their critical roles as carriers of therapeutic targets such as microRNAs (miRNAs) in the treatment of ...

    Authors: Mengzhi Wan, Caiju Lu, Yu Liu, Feng Luo, Jing Zhou and Fei Xu
    Citation: Respiratory Research 2023 24:233
  19. The clinical significance of Stenotrophomonas maltophilia in patients with COPD is poorly understood. We aimed to determine whether a lower respiratory tract culture positive for S. maltophilia in COPD patients w...

    Authors: Christian Rønn, Peter Kamstrup, Josefin Eklöf, Louise Lindhardt Toennesen, Jonas Bredtoft Boel, Christian Ostergaard Andersen, Ram Benny Dessau, Jon Torgny Wilcke, Pradeesh Sivapalan, Charlotte Suppli Ulrik and Jens-Ulrik Stæhr Jensen
    Citation: Respiratory Research 2023 24:232
  20. Asthma is a common, chronic inflammatory disease of the airways that affects millions of people worldwide and is associated with significant healthcare costs. Eosinophils, a type of immune cell, play a critica...

    Authors: Kunlu Shen, Mengyuan Zhang, Ruiheng Zhao, Yun Li, Chunxiao Li, Xin Hou, Bingqing Sun, Bowen Liu, Min Xiang and Jiangtao Lin
    Citation: Respiratory Research 2023 24:231
  21. Venovenous extracorporeal membrane oxygenation (vvECMO) is used to treat hypoxia in patients with severe acute respiratory distress syndrome (ARDS). Nevertheless, uncertainty exists regarding the optimal timin...

    Authors: Peter Rosenberger, Lisa Korell, Helene A. Haeberle, Valbona Mirakaj, Alice Bernard, Linyan Tang, Andreas Körner, Peter Martus and Michael Koeppen
    Citation: Respiratory Research 2023 24:230
  22. Triple therapy is recommended for patients with chronic obstructive pulmonary disease (COPD) who remain symptomatic despite dual therapy. The optimal timing of triple therapy following an exacerbation of COPD ...

    Authors: Afisi S. Ismaila, Kieran J. Rothnie, Robert P. Wood, Victoria L. Banks, Lucinda J. Camidge, Alexandrosz Czira, Chris Compton, Raj Sharma, Shannon N. Millard, Olivia Massey and David M. G. Halpin
    Citation: Respiratory Research 2023 24:229
  23. Authors: Stefania Lo Cicero, Germana Castelli, Giovanna Blaconà, Sabina Maria Bruno, Giovanni Sette, Riccardo Pigliucci, Valeria Rachela Villella, Speranza Esposito, Immacolata Zollo, Francesca Spadaro, Ruggero De Maria, Mauro Biffoni, Giuseppe Cimino, Felice Amato, Marco Lucarelli and Adriana Eramo
    Citation: Respiratory Research 2023 24:228

    The original article was published in Respiratory Research 2023 24:217

  24. Functional alveolar regeneration is essential for the restoration of normal lung homeostasis after acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Lung is a relatively quiescent organ a...

    Authors: Jianhui Sun, Huacai Zhang, Di Liu, Wenyi Liu, Juan Du, Dalin Wen, Luoxi Li, Anqiang Zhang, Jianxin Jiang and Ling Zeng
    Citation: Respiratory Research 2023 24:227
  25. Small airways disease plays a key role in the pathogenesis of chronic obstructive pulmonary disease (COPD) and is a major cause of obstruction; therefore, it is a critical pharmacotherapy target. This study ev...

    Authors: Omar Usmani, Grace Li, Jan De Backer, Hosein Sadafi, Libo Wu and Jonathan Marshall
    Citation: Respiratory Research 2023 24:226
  26. Sensitization to Staphylococcus aureus enterotoxins A (SEA) and B (SEB) has been associated with asthma severity, exacerbations, and disease control. Our study aimed to investigate if there are differences in ...

    Authors: Meropi Karakioulaki, Caroline Maria Berkemeier, Ingmar Heijnen, Leticia Grize, Eleni Papakonstantinou, Antonis Goulas, Michael Tamm and Daiana Stolz
    Citation: Respiratory Research 2023 24:225
  27. Muscle loss is prevalent in chronic obstructive pulmonary disease (COPD). Prior studies evaluating musculoskeletal dysfunction in COPD have focused on individuals with baseline low muscle mass. Currently, ther...

    Authors: Richard H. Zou, S. Mehdi Nouraie, Chad Karoleski, Yingze Zhang, Frank C. Sciurba, Daniel E. Forman and Jessica Bon
    Citation: Respiratory Research 2023 24:224
  28. Achieving and maintaining a low-risk profile is associated with favorable outcome in pulmonary arterial hypertension (PAH). The effects of treatment on risk profile are variable among patients.

    Authors: Agustin R. Garcia, Isabel Blanco, Lluis Ramon, Jesús Pérez-Sagredo, Francisco J. Guerra-Ramos, Clara Martín-Ontiyuelo, Olga Tura-Ceide, Francisco Pastor-Pérez, Pilar Escribano-Subías and Joan A. Barberà
    Citation: Respiratory Research 2023 24:223
  29. Idiopathic pulmonary fibrosis (IPF) bears high mortality due to unclear pathogenesis and limited therapeutic options. Therefore, identifying novel regulators is required to develop alternative therapeutic stra...

    Authors: Mingting Wu, Zhenyan Wang, Xiaoqian Shi, Danni Zan, Hong Chen, Shuqiao Yang, Fangping Ding, Liu Yang, Pingping Tan, Runlin Z. Ma, Jing Wang, Lishuang Ma, Yingmin Ma and Jiawei Jin
    Citation: Respiratory Research 2023 24:222
  30. Although asthma and chronic obstructive pulmonary disease (COPD) are two distinct chronic airway inflammatory diseases, they often co-exist in a patient and the condition is referred to as asthma-COPD overlap ...

    Authors: Surajit Dey, Wenying Lu, Greg Haug, Collin Chia, Josie Larby, Heinrich C. Weber, Archana Vijay Gaikwad, Prem Bhattarai, Affan Mahmood Shahzad, Prabuddha S. Pathinayake, Peter A. B. Wark, Mathew Suji Eapen and Sukhwinder Singh Sohal
    Citation: Respiratory Research 2023 24:221
  31. Pulmonary arterial hypertension is a major cause of death in systemic lupus erythematosus, but there are no tools specialized for predicting survival in systemic lupus erythematosus-associated pulmonary arteri...

    Authors: Jingge Qu, Mengtao Li, Xiao Zhang, Miaojia Zhang, Xiaoxia Zuo, Ping Zhu, Shuang Ye, Wei Zhang, Yi Zheng, Wufang Qi, Yang Li, Zhuoli Zhang, Feng Ding, Jieruo Gu, Yi Liu, Junyan Qian…
    Citation: Respiratory Research 2023 24:220
  32. Serum biomarkers in the evaluation of organ involvement and prognostic monitoring of sarcoidosis have not been determined. The purpose of this study was to identify common biomarkers that could be used to asse...

    Authors: Ying Zhou, Xianqiu Chen, Mengmeng Zhao, Elyse E. Lower and Robert P. Baughman
    Citation: Respiratory Research 2023 24:219
  33. Environmental co-exposure to allergen and traffic-related air pollution is common globally and contributes to the exacerbation of respiratory diseases. Individual responses to environmental insults remain vari...

    Authors: Andrew Robinson, Ryan D. Huff, Min Hyung Ryu and Chris Carlsten
    Citation: Respiratory Research 2023 24:218
  34. Cystic fibrosis (CF) is caused by defects of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. CFTR-modulating drugs may overcome specific defects, such as the case of Trikafta, which is a c...

    Authors: Stefania Lo Cicero, Germana Castelli, Giovanna Blaconà, Sabina Maria Bruno, Giovanni Sette, Riccardo Pigliucci, Valeria Rachela Villella, Speranza Esposito, Immacolata Zollo, Francesca Spadaro, Ruggero De Maria, Mauro Biffoni, Giuseppe Cimino, Felice Amato, Marco Lucarelli and Adriana Eramo
    Citation: Respiratory Research 2023 24:217

    The Correction to this article has been published in Respiratory Research 2023 24:228

  35. Macrophage migration inhibitory factor (MIF) and GTPase dynamin-related protein 1 (Drp1)-dependent aberrant mitochondrial fission are closely linked to the pathogenesis of asthma. However, it is unclear whethe...

    Authors: Jin Liu, Yuqian Chen, Huan Chen, Yan Wang, Danyang Li, Qianqian Zhang, Limin Chai, Yuanjie Qiu, Jia Zhang, Nirui Shen, Qingting Wang, Jian Wang and Manxiang Li
    Citation: Respiratory Research 2023 24:216
  36. X-ray velocimetry (XV) has been utilized in preclinical models to assess lung motion and regional ventilation, though no studies have compared XV-derived physiologic parameters to measures derived through conv...

    Authors: Trishul Siddharthan, Kyle Grealis, Jason P. Kirkness, Tamás Ötvös, Darko Stefanovski, Alex Tombleson, Molly Dalzell, Ernesto Gonzalez, Kinjal Bhatt Nakrani, David Wenger, Michael G. Lester, Bradley W. Richmond, Andreas Fouras and Naresh M. Punjabi
    Citation: Respiratory Research 2023 24:215
  37. Idiopathic pulmonary fibrosis (IPF) is a chronically progressive fibrotic pulmonary disease characterized by an uncertain etiology, a poor prognosis, and a paucity of efficacious treatment options. Dexmedetomi...

    Authors: Xiaofan Lai, Yingying Lin, Shaojie Huang, Lvya Pu, Qihao Zeng, Zhongxing Wang and Wenqi Huang
    Citation: Respiratory Research 2023 24:214
  38. The airway epithelium is composed of diverse cell types with specialized functions that mediate homeostasis and protect against respiratory pathogens. Human airway epithelial (HAE) cultures at air–liquid inter...

    Authors: Rachel A. Prescott, Alec P. Pankow, Maren de Vries, Keaton M. Crosse, Roosheel S. Patel, Mark Alu, Cynthia Loomis, Victor Torres, Sergei Koralov, Ellie Ivanova, Meike Dittmann and Brad R. Rosenberg
    Citation: Respiratory Research 2023 24:213
  39. Previous studies have shown that IL-25 levels are increased in patients with asthma with fixed airflow limitation (FAL). However, the mechanism by which IL-25 contributes to airway remodeling and FAL remains u...

    Authors: Xiujuan Yao, Qinglin Chen, Xiangdong Wang, Xiaofang Liu and Luo Zhang
    Citation: Respiratory Research 2023 24:212
  40. Pulmonary fibrosis is a progressive disease characterized by lung remodeling due to excessive deposition of extracellular matrix. Although the etiology remains unknown, aberrant angiogenesis and inflammation p...

    Authors: Laura Cucinotta, Deborah Mannino, Giovanna Casili, Alberto Repici, Lelio Crupi, Irene Paterniti, Emanuela Esposito and Michela Campolo
    Citation: Respiratory Research 2023 24:211
  41. Authors: Haruko Takeuchi, S. M. Tafsir Hasan, Khalequ Zaman, Sayaka Takanashi, Samar Kumar Hore, Sultana Yeasmin, Shaikh Meshbahuddin Ahmad, Md Jahangir Alam, Masamine Jimba, Tsutomu Iwata and Md Alfazal Khan
    Citation: Respiratory Research 2023 24:210

    The original article was published in Respiratory Research 2021 22:35

  42. Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung disease characterised by decline in lung function. We evaluated trajectories of forced vital capacity (FVC) and diffusing capaci...

    Authors: Megan L Neely, Anne S Hellkamp, Shaun Bender, Jamie L Todd, Timothy Liesching, Tracy R Luckhardt, Justin M Oldham, Rishi Raj, Eric S White and Scott M Palmer
    Citation: Respiratory Research 2023 24:209
  43. Non-invasive ventilation (NIV) is an evidence-based treatment for acute respiratory failure in chronic obstructive pulmonary disease (COPD). However, suboptimal application of NIV in clinical practice, possibl...

    Authors: Judith Elshof, Judith M. Vonk, Anouschka van der Pouw, Cella van Dijk, Petra Vos, Huib A.M. Kerstjens, Peter J. Wijkstra and Marieke L. Duiverman
    Citation: Respiratory Research 2023 24:208
  44. Acute exacerbations of chronic inflammatory lung diseases, such as chronic obstructive pulmonary disease (COPD), are frequently associated with rhinovirus (RV) infections. Despite these associations, the path...

    Authors: Ying Wang, Dennis K. Ninaber, Alen Faiz, Abraham C. van der Linden, Annemarie van Schadewijk, René Lutter, Pieter S. Hiemstra, Anne M. van der Does and Abilash Ravi
    Citation: Respiratory Research 2023 24:207
  45. Due to the high risk of COVID-19 patients developing thrombosis in the circulating blood, atherosclerosis, and myocardial infarction, it is necessary to study the lipidome of erythrocytes. Specifically, we exa...

    Authors: Alaa Khedr, Maan T. Khayat, Ahdab N. Khayyat, Hany Z. Asfour, Rahmah A. Alsilmi and Ahmed K. Kammoun
    Citation: Respiratory Research 2023 24:206
  46. Rhinovirus (RV) infection of airway epithelial cells triggers asthma exacerbations, during which airway smooth muscle (ASM) excessively contracts. Due to ASM contraction, airway epithelial cells become mechani...

    Authors: Alane Blythe C. Dy, Jason Girkin, Antonella Marrocco, Adam Collison, Chimwemwe Mwase, Michael J. O’Sullivan, Thien-Khoi N. Phung, Joerg Mattes, Cynthia Koziol-White, James E. Gern, Yury A. Bochkov, Nathan W. Bartlett and Jin-Ah Park
    Citation: Respiratory Research 2023 24:205
  47. Pulmonary hypertension (PH) is a lethal vascular disease with limited therapeutic options. The mechanistic connections between alveolar hypoxia and PH are not well understood. The aim of this study was to inve...

    Authors: Rongrong Chen, Hongfei Wang, Cuiting Zheng, Xiyu Zhang, Li Li, Shengwei Wang, Hongyu Chen, Jing Duan, Xian Zhou, Haiyong Peng, Jing Guo, Anchen Zhang, Feifei Li, Wang Wang, Yu Zhang, Jun Wang…
    Citation: Respiratory Research 2023 24:204
  48. A growing body of evidence suggests that use of race terms in spirometry reference equations underestimates disease burden in Black populations, which may lead to disparities in pulmonary disease outcomes. Dat...

    Authors: Allison J. Burbank, Claire E. Atkinson, Andre E. Espaillat, Stephen A. Schworer, Katherine Mills, Jennifer Rooney, Ceila E. Loughlin, Wanda Phipatanakul and Michelle L. Hernandez
    Citation: Respiratory Research 2023 24:203
  49. Right heart failure is the leading cause of death in pulmonary hypertension (PH), and echocardiography is a commonly used tool for evaluating the risk hierarchy of PH. However, few studies have explored the dy...

    Authors: Meidan Kuang, Yilin Chen, Yue Xing, Min Du, Huazhuo Feng, Qifeng Yang, Dongmei Wen, Xuanyi Li, Kai Yang, Ziying Lin, Ning Lai, Qian Jiang, Shiyun Liu, Dansha Zhou, Wei Hong, Xin Fu…
    Citation: Respiratory Research 2023 24:202
  50. Alveolar macrophages (AMs) and AM-produced matrix metalloprotease (MMP)-12 are known to play critical roles in the pathogenesis of chronic obstructive pulmonary disease (COPD). The apoptosis inhibitor of the m...

    Authors: Michiko Takimoto-Sato, Masaru Suzuki, Hiroki Kimura, Haiyan Ge, Munehiro Matsumoto, Hironi Makita, Satoko Arai, Toru Miyazaki, Masaharu Nishimura and Satoshi Konno
    Citation: Respiratory Research 2023 24:201

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