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  1. Access to timely and accurate diagnostic imaging is essential for high-quality healthcare. Point-of-care ultrasound has been shown to be accessible and effective in many aspects of healthcare, including assess...

    Authors: Nika Elmi, Yasmin Sadri, Frank Myslik, Jordan Chenkin and William Cherniak
    Citation: Respiratory Research 2024 25:111
  2. Acute lung injury (ALI) is one of the life-threatening complications of sepsis, and macrophage polarization plays a crucial role in the sepsis-associated ALI. However, the regulatory mechanisms of macrophage p...

    Authors: Wenhui Huang, Lianfang Wang, Zhipeng Huang, Zhichao Sun and Bojun Zheng
    Citation: Respiratory Research 2024 25:110
  3. There is an argument whether the delayed intubation aggravate the respiratory failure in Acute respiratory distress syndrome (ARDS) patients with coronavirus disease 2019 (COVID-19). We aimed to investigate th...

    Authors: Dong-gon Hyun, Su Yeon Lee, Jee Hwan Ahn, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh and Jin Won Huh
    Citation: Respiratory Research 2024 25:109
  4. Acute lung injury (ALI) is a devastating clinical disorder with a high mortality rate, and there is an urgent need for more effective therapies. Fibroblast growth factor 18 (FGF18) has potent anti-inflammatory...

    Authors: Zhenyu Hu, Jindan Dai, Tianpeng Xu, Hui Chen, Guoxiu Shen, Jie Zhou, Hongfang Ma, Yang Wang and Litai Jin
    Citation: Respiratory Research 2024 25:108
  5. Targeting receptor-interacting serine/threonine protein kinase 1 could mitigate the devastating sequelae of the hyperinflammatory state observed in severe cases of COVID-19. This study explored the immunomodul...

    Authors: Pierre-Francois Clot, Christine Farenc, Benjamin T. Suratt, Tillmann Krahnke, Agnes Tardat, Peter Florian, Robert Pomponio, Naimish Patel, Maria Wiekowski, Yong Lin, Benjamin Terrier and Heribert Staudinger
    Citation: Respiratory Research 2024 25:107
  6. Small airways disease (SAD) is a major cause of airflow obstruction in COPD patients and has been identified as a precursor to emphysema. Although the amount of SAD in the lungs can be quantified using our Par...

    Authors: Alexander J. Bell, Ravi Pal, Wassim W. Labaki, Benjamin A. Hoff, Jennifer M. Wang, Susan Murray, Ella A. Kazerooni, Stefanie Galban, David A. Lynch, Stephen M. Humphries, Fernando J. Martinez, Charles R. Hatt, MeiLan K. Han, Sundaresh Ram and Craig J. Galban
    Citation: Respiratory Research 2024 25:106
  7. Increasing evidence is appearing that ozone has adverse effects on health. However, the association between long-term ozone exposure and lung function is still inconclusive.

    Authors: Shurong Feng, Liu Yang, Siqi Dou, Xinyuan Li, Shuo Wen, Lailai Yan, Wenzhong Huang, Yiwen Zhang, Bin Ma, Linghong Yuan, Shanshan Li, Peng Lu and Yuming Guo
    Citation: Respiratory Research 2024 25:105
  8. Airway epithelial cells (AECs) are a major component of local airway immune responses. Direct effects of type 2 cytokines on AECs are implicated in type 2 asthma, which is driven by epithelial-derived cytokine...

    Authors: Maria Gabriella Matera, Barbara Rinaldi, Cecilia Calabrese, Carmela Belardo, Luigino Calzetta, Mario Cazzola and Clive Page
    Citation: Respiratory Research 2024 25:104
  9. The prognostic role of changes in body fat in patients with idiopathic pulmonary fibrosis (IPF) remains underexplored. We investigated the association between changes in body fat during the first year post-dia...

    Authors: Ji Young Lee, Soon Ho Yoon, Jin Mo Goo, Jimyung Park and Jong Hyuk Lee
    Citation: Respiratory Research 2024 25:103
  10. Seasonally circulating viruses, such as Influenza, as well as newly emerging viruses and variants thereof, and waning immunity urge the need for safe, easy-to-use and inexpensive drugs to protect from these ch...

    Authors: Viktoria Zaderer, Gabriel Diem, Wilfried Posch, Thomas Jakschitz, Günther K. Bonn, Rosa Bellmann-Weiler, Lukas A. Huber and Doris Wilflingseder
    Citation: Respiratory Research 2024 25:102
  11. Although some studies have indicated that Psoriasis could contribute to the risk of idiopathic pulmonary fibrosis (IPF), no study has reported a clear causal association between them. Our aim was to explore th...

    Authors: Lingli Chen, Yujie Wei, Mengjin Hu, Yile Liu and Xiangrong Zheng
    Citation: Respiratory Research 2024 25:101
  12. Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) as common life-threatening lung diseases with high mortality rates are mostly associated with acute and severe infla...

    Authors: Xingxing Hu, Menglin Zou, Weishuai Zheng, Minghui Zhu, Qinhui Hou, Han Gao, Xin Zhang, Yuan Liu and Zhenshun Cheng
    Citation: Respiratory Research 2024 25:100
  13. Intra-breath oscillometry has been proposed as a sensitive means of detecting airway obstruction in young children. We aimed to assess the impact of early life wheezing and lower respiratory tract illness on l...

    Authors: Valérie Siroux, Anne Boudier, Sarah Lyon-Caen, Joane Quentin, Yoann Gioria, Zoltán Hantos, Rémy Slama, Isabelle Pin and Sam Bayat
    Citation: Respiratory Research 2024 25:99
  14. COVID-19 is an abnormal host response to the SARS-CoV-2 infection, which is associated with endothelial dysfunction and multi-organ failure. Atorvastatin has been proposed to reduce COVID-19 severity and morta...

    Authors: Naglaa Hamdi Eltahan, Neamat Hamdy Elsawy, Kholoud M. Abdelaaty, Amal Salah Elhamaky, Ahmed H. Hassan and Moataz Maher Emara
    Citation: Respiratory Research 2024 25:97
  15. Solid nodules (SN) had more aggressive features and a poorer prognosis than part-solid nodules (PSN). This study aimed to evaluate the specific impacts of nodule radiological appearance (SN vs. PSN) on lymph n...

    Authors: Zhihua Li, Cheng Pan, Wenzheng Xu, Chen Zhao, Xianglong Pan, Zhibo Wang, Weibing Wu and Liang Chen
    Citation: Respiratory Research 2024 25:96
  16. COVID-19 patients with preexisting interstitial lung disease (ILD) were reported to have a high mortality rate; however, this was based on data from the early stages of the pandemic. It is uncertain how their ...

    Authors: Koichi Miyashita, Hironao Hozumi, Kazuki Furuhashi, Eiji Nakatani, Yusuke Inoue, Hideki Yasui, Yuzo Suzuki, Masato Karayama, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Toshiyuki Ojima and Takafumi Suda
    Citation: Respiratory Research 2024 25:95
  17. Allergic diseases exert a considerable impact on global health, thus necessitating investigations into their etiology and pathophysiology for devising effective prevention and treatment strategies. This study ...

    Authors: Junhao Tu, Jinyang Wen, Qing Luo, Xin Li, Deyun Wang and Jing Ye
    Citation: Respiratory Research 2024 25:94
  18. Chronic obstructive pulmonary disease (COPD) is a common respiratory disease and represents the third leading cause of death worldwide. This study aimed to investigate miRNA regulation of Receptor for Advanced...

    Authors: Chenli Chang, Ke Huang, Xia Xu, Ruirui Duan, Tao Yu, Xu Chu, Chen Chen, Baicun Li and Ting Yang
    Citation: Respiratory Research 2024 25:93
  19. Interstitial lung disease encompasses a group of rare lung conditions causing inflammation and scarring of lung tissue. The typical method of monitoring disease activity is through pulmonary function tests per...

    Authors: Ryan D. Boente, Sydney Schacht, Rebecca Borton, Joseph Vincent, Lilian Golzarri-Arroyo and Nicholas Rattray
    Citation: Respiratory Research 2024 25:92
  20. Prior studies in patients with chronic obstructive pulmonary disease (COPD) had indicated a potential correlation between cadmium (Cd) exposure and reduction in lung function. Nevertheless, the influence of Cd...

    Authors: Jing Sun, You-Peng Deng, Juan Xu, Feng-Min Zhu, Qi-Yuan He, Min-Min Tang, Ying Liu, Jin Yang, Hong-Yan Liu, Lin Fu and Hui Zhao
    Citation: Respiratory Research 2024 25:91
  21. Exposure to PM2.5 has been implicated in a range of detrimental health effects, particularly affecting the respiratory system. However, the precise underlying mechanisms remain elusive.

    Authors: Li Luo, Manling Jiang, Ying Xiong, Anying Xiong, Lei Zhang, Dehong Wu, Yao Liu, Qin Ran, Jiliu Liu, Yi Zhang, Jiahuan Li, Xiang He, Junyi Wang and Guoping Li
    Citation: Respiratory Research 2024 25:90
  22. The morbidity and mortality among hospital inpatients with AECOPD and CVDs remains unacceptably high. Currently, no risk score for predicting mortality has been specifically developed in patients with AECOPD a...

    Authors: Jiarui Zhang, Qun Yi, Chen Zhou, Yuanming Luo, Hailong Wei, Huiqing Ge, Huiguo Liu, Jianchu Zhang, Xianhua Li, Xiufang Xie, Pinhua Pan, Mengqiu Yi, Lina Cheng, Hui Zhou, Liang Liu, Adila Aili…
    Citation: Respiratory Research 2024 25:89
  23. Long-term outcomes of lung transplantation (LTx) remain hampered by chronic lung allograft dysfunction (CLAD). Matrix metalloproteinase 9 (MMP-9) is a secretory endopeptidase identified as a key mediator in fi...

    Authors: Adrien Tissot, Eugénie Durand, Thomas Goronflot, Benjamin Coiffard, Benjamin Renaud-Picard, Antoine Roux, Xavier Demant, Jean-François Mornex, Loïc Falque, Mathilde Salpin, Jérôme Le Pavec, Thomas Villeneuve, Véronique Boussaud, Christiane Knoop, Antoine Magnan, David Lair…
    Citation: Respiratory Research 2024 25:88
  24. After a fortuitous observation of two cases of chemosensitivity recovery in women with congenital central hypoventilation syndrome (CCHS) who took desogestrel, we aimed to evaluate the ventilatory response to ...

    Authors: Caroline Sevoz-Couche, Maxime Patout, Beny Charbit, Thomas Similowski and Christian Straus
    Citation: Respiratory Research 2024 25:87
  25. Bronchopulmonary Dysplasia (BPD) in infants born prematurely is a risk factor for chronic airway obstruction later in life. The distribution of T cell subtypes in the large airways is largely unknown.

    Authors: Jing Gao, Petra Um-Bergström, Melvin Pourbazargan, Eva Berggren-Broström, ChuanXing Li, Heta Merikallio, Riitta Kaarteenaho, Nichole Stacey Reinke, Craig E Wheelock, Erik Melén, Lindén Anders, Åsa M Wheelock, Georgios Rassidakis, Cristian Ortiz-Villalon and Magnus Carl Sköld
    Citation: Respiratory Research 2024 25:86
  26. Chronic obstructive pulmonary disease (COPD) and asthma associate with high morbidity and mortality. High levels of advanced glycation end products (AGEs) were found in tissue and plasma of COPD patients but t...

    Authors: Tianqi Lu, Lies Lahousse, Sara Wijnant, Jinluan Chen, Guy G. Brusselle, Mandy van Hoek and M. Carola Zillikens
    Citation: Respiratory Research 2024 25:85
  27. Post COVID-19 syndrome is characterized by several cardiorespiratory symptoms but the origin of patients’ reported symptomatology is still unclear.

    Authors: Piergiuseppe Agostoni, Massimo Mapelli, Elisabetta Salvioni, Irene Mattavelli, Cristina Banfi, Alice Bonomi, Maria Luisa Biondi, Sara Rovai, Gloria Tamborini, Manuela Muratori, Sarah Ghulam Ali, Stefania Ghilardi, Fabiana De Martino, Carlo Vignati, Pietro Palermo, Paola Gugliandolo…
    Citation: Respiratory Research 2024 25:82
  28. Idiopathic pulmonary fibrosis (IPF) is a progressive disease associated with high mortality. Low muscle mass, frailty and sarcopenia lead to functional impairment that negatively impact quality of life and sur...

    Authors: Meenakshi Sridhar, Sandeep Bodduluri, Lanier O’Hare, Scott Blumhoff, Maria del Pilar Acosta Lara, Joao A. de Andrade, Young-Il Kim, Tracy Luckhardt, MerryLynn McDonald and Tejaswini Kulkarni
    Citation: Respiratory Research 2024 25:81
  29. The latest European Society of Cardiology and European Respiratory Society guidelines have changed the definition of both pre-capillary pulmonary hypertension (PH) and severe PH in chronic lung disease. The cl...

    Authors: Shameek K. Gayen, Mary Zulty and Gerard J. Criner
    Citation: Respiratory Research 2024 25:79
  30. Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited treatment options. Circular RNAs (circRNAs) have emerged as a novel class of non-coding RNAs with diverse functions in c...

    Authors: Akshaya Surendran, Chaoqun Huang and Lin Liu
    Citation: Respiratory Research 2024 25:77
  31. Asthma is a heterogeneous disease characterized by airway inflammation and remodeling, whose pathogenetic complexity was associated with abnormal responses of various cell types in the lung. The specific inter...

    Authors: Xiu Yu, Lifei Li, Bicheng Cai, Wei Zhang, Quan Liu, Nan Li, Xing Shi, Li Yu, Rongchang Chen and Chen Qiu
    Citation: Respiratory Research 2024 25:76
  32. Electronic cigarettes (EC) have gained popularity, especially among young people, with the introduction of fourth-generation devices based on e-liquids containing nicotine salts that promise a smoother vaping ...

    Authors: Clément Mercier, Jérémie Pourchez, Lara Leclerc and Valérie Forest
    Citation: Respiratory Research 2024 25:75
  33. DNA methylation regulators (DMRs) play a key role in DNA methylation, thus mediating tumor occurrence, metastasis, and immunomodulation. However, the effects of DMRs on clinical outcomes and immunotherapy resp...

    Authors: Jing Huang, Chujian Huang, Can Huang, Zichang Xiang, Yao Ni, Jian Zeng and Songhua Cai
    Citation: Respiratory Research 2024 25:74
  34. Pneumocystis pneumonia (PCP) is a life-threatening opportunistic fungal infection with a high mortality rate in immunocompromised patients, ranging from 20 to 80%. However, current understanding of the variation ...

    Authors: Hu-Qin Yang, Han Sun, Kang Li, Ming-Ming Shao, Kan Zhai and Zhao-Hui Tong
    Citation: Respiratory Research 2024 25:72
  35. Since the worldwide spread of SARS-CoV-2, different strategies have been followed to combat the pandemic and limit virus transmission. In the meantime, other respiratory viruses continued to circulate, though ...

    Authors: Jaqueline Rhoden, Andressa Taíz Hoffmann, Janaína Franciele Stein, Bruna Seixas da Rocha, Vinícius Monteagudo de Barros, Eduardo Viegas da Silva, Juliane Deise Fleck and Caroline Rigotto
    Citation: Respiratory Research 2024 25:71
  36. Currently, there are no reliable clinical tools that allow non-invasive therapeutic support for patients with pulmonary arterial hypertension. This study aims to propose a low-frequency ultrasound device for p...

    Authors: Vytautas Ostasevicius, Vytautas Jurenas, Mantas Venslauskas, Laura Kizauskiene, Vilma Zigmantaite, Edgaras Stankevicius, Algimantas Bubulis, Joris Vezys and Sandra Mikuckyte
    Citation: Respiratory Research 2024 25:70
  37. Although multidrug-resistant bacteria (MDR) are common in patients undergoing prolonged weaning, there is little data on their impact on weaning and patient outcomes.

    Authors: Julia D. Michels-Zetsche, Vicky Gassmann, Jasmin K. Jasuja, Benjamin Neetz, Philipp Höger, Jan Meis, Simone Britsch, Urte Sommerwerck, Sebastian Fähndrich, Florian Bornitz, Michael M. Müller, Felix J.F. Herth and Franziska C. Trudzinski
    Citation: Respiratory Research 2024 25:69
  38. Metagenomic next-generation sequencing (mNGS), as an emerging technique for pathogen detection, has been widely used in clinic. However, reports on the application of mNGS in cancer patients with severe pneumo...

    Authors: Chao Wang, Xiaojuan Yin, Wenqing Ma, Li Zhao, Xuhong Wu, Nan Ma, Yuepeng Cao, Quanli Zhang, Shuliang Ma, Lin Xu and Xuerong Wang
    Citation: Respiratory Research 2024 25:68
  39. Chronic obstructive pulmonary disease (COPD) is a leading aging related cause of global mortality. Small airway narrowing is recognized as an early and significant factor for COPD development. Senescent fibrob...

    Authors: Fang Lu, Li-peng Yao, Dan-dan Gao, Tahereh Alinejad, Xin-qing Jiang, Qi Wu, Qiao-cheng Zhai, Ming Liu, Sheng-mei Zhu, Mao-xiang Qian, Li-feng Xu, Cheng-shui Chen and Feng Zhang
    Citation: Respiratory Research 2024 25:67
  40. Small airway remodelling is a vital characteristic of chronic obstructive pulmonary disease (COPD), which is mainly caused by epithelial barrier dysfunction and epithelial-mesenchymal transition (EMT). Recent ...

    Authors: Qin Zhang, Liming Yan, Ye Lu, Xiaodong Liu, Yan Yin, Qiuyue Wang, Xiu Gu and Xiaoming Zhou
    Citation: Respiratory Research 2024 25:66
  41. Endobronchial ultrasound (EBUS) and cone-beam computed tomography-derived augmented fluoroscopy (CBCT-AF) are utilized for the diagnosis of peripheral pulmonary lesions (PPLs). Combining them with transbronchi...

    Authors: Ching-Kai Lin, Sheng-Yuan Ruan, Hung-Jen Fan, Hao-Chun Chang, Yen-Ting Lin and Chao-Chi Ho
    Citation: Respiratory Research 2024 25:65
  42. Among patients with chronic obstructive pulmonary disease (COPD), some have features of both asthma and COPD—a condition categorized as asthma-COPD overlap (ACO). Our aim was to determine whether asthma- or CO...

    Authors: Yu-Ping Chang, Yi-Hsuan Tsai, Yu-Mu Chen, Kuo-Tung Huang, Chiu-Ping Lee, Po-Yuan Hsu, Hung-Chen Chen, Meng-Chih Lin and Yung-Che Chen
    Citation: Respiratory Research 2024 25:64

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