Skip to main content

Articles

Page 1 of 77

  1. Severe dysphagia can cause intractable pneumonia and lead to life-threatening conditions. Intractable aspiration can occur despite medical management for aspiration prevention. Surgical intervention is indicat...

    Authors: Rumi Ueha, Redentor B. Magdayao, Misaki Koyama, Taku Sato, Takao Goto and Tatsuya Yamasoba
    Citation: Respiratory Research 2023 24:43
  2. Clinical and experimental evidence shows lung fluid volume as a modulator of fetal lung growth with important value in treating fetal lung hypoplasia. Thus, understanding the mechanisms underlying these morpho...

    Authors: Ana N. Gonçalves, Rute S. Moura, Jorge Correia-Pinto and Cristina Nogueira-Silva
    Citation: Respiratory Research 2023 24:42
  3. Alpha-1-antitrypsin deficient (AATD) individuals are prone to develop early age of onset chronic obstructive pulmonary disease (COPD) more severe than non-genetic COPD. Here, we investigated the characteristic...

    Authors: Nurdan Kokturk, Nazli Khodayari, Jorge Lascano, E. Leonard Riley and Mark L. Brantly
    Citation: Respiratory Research 2023 24:40
  4. Ibuprofen is a nonsteroidal anti-inflammatory drug that is commonly used to stimulate closure of a patent ductus arteriosus (PDA) in very premature infants and may lead to aberrant neonatal lung development an...

    Authors: Xueyu Chen, Dongshan Han, Xuan Wang, Xuemei Huang, Zilu Huang, Yijun Liu, Junyan Zhong, Frans J. Walther, Chuanzhong Yang and Gerry T. M. Wagenaar
    Citation: Respiratory Research 2023 24:39
  5. The association between genetic variants on the X chromosome to risk of COPD has not been fully explored. We hypothesize that the X chromosome harbors variants important in determining risk of COPD related phe...

    Authors: Lystra P. Hayden, Brian D. Hobbs, Robert Busch, Michael H. Cho, Ming Liu, Camila M. Lopes-Ramos, David A. Lomas, Per Bakke, Amund Gulsvik, Edwin K. Silverman, James D. Crapo, Terri H. Beaty, Nan M. Laird, Christoph Lange and Dawn L. DeMeo
    Citation: Respiratory Research 2023 24:38
  6. Previous studies have indicated that lower lung function is related to a higher risk of venous thromboembolism (VTE). However, causal inferences may be affected by confounders, coheritability or reverse causal...

    Authors: Qiaoyun Zhang, Xiaoyu Zhang, Jie Zhang, Mengyang Jiang, Yiqiang Zhang, Deqiang Zheng, Lijuan Wu, Wei Wang, Baoguo Wang and Youxin Wang
    Citation: Respiratory Research 2023 24:36
  7. Alpha-1-antitrypsin (AAT) deficiency (AATD) is a genetic disorder that can manifest as lung disease. A delay between onset of symptoms and diagnosis of AATD is common and associated with worse clinical status ...

    Authors: Tobias Meischl, Karin Schmid-Scherzer, Florian Vafai-Tabrizi, Gert Wurzinger, Eva Traunmüller-Wurm, Kristina Kutics, Markus Rauter, Fikreta Grabcanovic-Musija, Simona Müller, Norbert Kaufmann, Judith Löffler-Ragg, Arschang Valipour and Georg-Christian Funk
    Citation: Respiratory Research 2023 24:34
  8. Pulmonary inflammation involves complex changes of the immune cells, in which macrophages play important roles and their function might be influenced by metabolism. Slc38a6 acts as a carrier of nutrient for ma...

    Authors: Yizhao Peng, Weichao Chen, Fumeng Huang, Manman Geng, Xiaowei Li, Fujun Zhang, Wenhua Zhu, Liesu Meng, Rikard Holmdahl, Jing Xu and Shemin Lu
    Citation: Respiratory Research 2023 24:33
  9. Lung transcriptomics studies in asthma have provided valuable information in the whole lung context, however, deciphering the individual contributions of the airway and parenchyma in disease pathogenesis may e...

    Authors: Xiaofan Tu, Henry M. Gomez, Richard Y. Kim, Alexandra C. Brown, Emma de Jong, Izabela Galvao, Alen Faiz, Anthony Bosco, Jay C. Horvat, Philip Hansbro and Chantal Donovan
    Citation: Respiratory Research 2023 24:32
  10. Chronic obstructive pulmonary disease (COPD) varies significantly in symptomatic and physiologic presentation. Identifying disease subtypes from molecular data, collected from easily accessible blood samples, ...

    Authors: Kristina L. Buschur, Craig Riley, Aabida Saferali, Peter Castaldi, Grace Zhang, Francois Aguet, Kristin G. Ardlie, Peter Durda, W. Craig Johnson, Silva Kasela, Yongmei Liu, Ani Manichaikul, Stephen S. Rich, Jerome I. Rotter, Josh Smith, Kent D. Taylor…
    Citation: Respiratory Research 2023 24:30
  11. Pulmonary Rehabilitation (PR) is one of the most cost-effective therapies for chronic obstructive pulmonary disease (COPD) management. There are, however, people who do not respond to PR and reasons for non-re...

    Authors: Sara Melo-Dias, Miguel Cabral, Andreia Furtado, Sara Souto-Miranda, Maria Aurora Mendes, João Cravo, Catarina Rodrigues Almeida, Alda Marques and Ana Sousa
    Citation: Respiratory Research 2023 24:29
  12. The Mesenchymal epithelial transition factor (MET) gene encodes a receptor tyrosine kinase with pleiotropic functions in cancer. MET exon 14 skipping alterations and high-level MET amplification are oncogenic and...

    Authors: Yu Yao, Huaping Yang, Bo Zhu, Song Wang, Jiaohui Pang, Xiaoying Wu, Yang Xu, Junli Zhang, Jinfeng Zhang, Qiuxiang Ou, Hui Tian and Zheng Zhao
    Citation: Respiratory Research 2023 24:28
  13. Severe bronchiolitis is often associated with subsequent respiratory morbidity, mainly recurrent wheezing and asthma. However, the underlying immune mechanisms remain unclear. The main goal of this study was t...

    Authors: Maria Luz Garcia-Garcia, Beatriz Sastre, Maria Arroyas, Maite Beato, Patricia Alonso, José Manuel Rodrigo-Muñoz, Victoria Del Pozo, Inmaculada Casas and Cristina Calvo
    Citation: Respiratory Research 2023 24:26
  14. Radiation-induced lung injury (RILI) is the most common and serious complication of chest radiotherapy. However, reported radioprotective agents usually lead to radiation resistance in tumor cells. The key to ...

    Authors: Xinrui Rao, Dong Zhou, Huilin Deng, Yunshang Chen, Jian Wang, Xiaoshu Zhou, Xiaohua Jie, Yingzhuo Xu, Zilong Wu, Geng Wang, Xiaorong Dong, Sheng Zhang, Rui Meng, Chuangyan Wu, Shijie Xing, Kai Fan…
    Citation: Respiratory Research 2023 24:25
  15. Advanced glycation end product receptor (RAGE) acts as a receptor of pro-inflammatory ligands and is highly expressed in alveolar epithelial cells (AECs). Autophagy in AECs has received much attention recently...

    Authors: Xi Xiong, Jiaying Dou, Jingyi Shi, Yuqian Ren, Chunxia Wang, Yucai Zhang and Yun Cui
    Citation: Respiratory Research 2023 24:24
  16. Low-dose spiral computed tomography (LDCT) may not lead to a clear treatment path when small to intermediate-sized lung nodules are identified. We have combined flow cytometry and machine learning to develop a...

    Authors: Madeleine E. Lemieux, Xavier T. Reveles, Jennifer Rebeles, Lydia H. Bederka, Patricia R. Araujo, Jamila R. Sanchez, Marcia Grayson, Shao-Chiang Lai, Louis R. DePalo, Sheila A. Habib, David G. Hill, Kathleen Lopez, Lara Patriquin, Robert Sussman, Roby P. Joyce and Vivienne I. Rebel
    Citation: Respiratory Research 2023 24:23
  17. Chronic obstructive pulmonary disease (COPD) is characterized by irreversible lung tissue damage. Novel regenerative strategies are urgently awaited. Cultured mesenchymal stem/stromal cells (MSCs) have shown p...

    Authors: Dennis Kruk, Anna C. Y. Yeung, Alen Faiz, Nick H. T. ten Hacken, Wim Timens, Toin H. van Kuppevelt, Willeke Daamen, Danique Hof, Martin C. Harmsen, Mauricio Rojas and Irene H. Heijink
    Citation: Respiratory Research 2023 24:22
  18. Receptor for Advanced Glycated Endproducts (RAGE) plays a major role in the inflammatory response to infectious and toxin induced acute lung injury. We tested the hypothesis that a RAGE blocking antibody when ...

    Authors: Lynne L. Johnson, Yared Tekabe, Tina Zelonina, Xinran Ma, Geping Zhang, Monica Goldklang and Jeanine D’Armiento
    Citation: Respiratory Research 2023 24:21
  19. Parameters from maximal expiratory flow-volume curves (MEFVC) have been linked to CT-based parameters of COPD. However, the association between MEFVC shape and phenotypes like emphysema, small airways disease ...

    Authors: Kenneth Verstraete, Nilakash Das, Iwein Gyselinck, Marko Topalovic, Thierry Troosters, James D. Crapo, Edwin K. Silverman, Barry J. Make, Elizabeth A. Regan, Robert Jensen, Maarten De Vos and Wim Janssens
    Citation: Respiratory Research 2023 24:20
  20. The objective of the present study is to describe the characteristics of interstitial pneumonia with autoimmune features (IPAF) patients, to assess the incidence rate of functional respiratory impairment over ...

    Authors: Maria Asuncion Nieto, Olga Sanchez-Pernaute, Cristina Vadillo, Maria Jesus Rodriguez-Nieto, Fredeswinda Romero-Bueno, Belen López-Muñiz, Laura Cebrian, Maria Teresa Rio-Ramirez, Rosalia Laporta, Gema Bonilla, Tatiana Cobo, Leticia Leon and Lydia Abasolo
    Citation: Respiratory Research 2023 24:19
  21. Epoprostenol AS (Veletri®), a thermostable epoprostenol formulation, provides better drug stability and improved clinical use compared to previous epoprostenol formulations. This study aims to expand clinical exp...

    Authors: Julia Degering, Benjamin Egenlauf, Satenik Harutyunova, Nicola Benjamin, Amina Salkić, Panagiota Xanthouli, Christina A. Eichstaedt, Rebekka Seeger, Olivier Sitbon and Ekkehard Grünig
    Citation: Respiratory Research 2023 24:18
  22. Molecular testing can detect actionable genomic alterations and tumor cell surface proteins in patients with non–small cell lung cancer (NSCLC). However, utilization remains suboptimal, representing missed tre...

    Authors: Florian J. Fintelmann, Nikki A. Martin, Ismail Tahir, Elissa M. Quinn, Timothy C. Allen, Lija Joseph, Boris Nikolic and Christopher Lee
    Citation: Respiratory Research 2023 24:17
  23. The level of linked N-acetylglucosamine (O-GlcNAc) has been proved to be a sensor of cell state, but its relationship with hyperoxia-induced alveolar type 2 epithelial cells injure and bronchopulmonary dysplas...

    Authors: Yu Xuefei, Liu Dongyan, Li Tianming, Zheng Hejuan and Fu Jianhua
    Citation: Respiratory Research 2023 24:16
  24. Chronic respiratory diseases are disorders of the airways and other structures of the lung, and include chronic obstructive pulmonary disease (COPD), lung cancer, asthma, bronchiectasis, interstitial lung dise...

    Authors: Gillian Sandra Gould, John R. Hurst, Antigona Trofor, Jennifer A. Alison, Gregory Fox, Muralidhar M. Kulkarni, Craig E. Wheelock, Marilyn Clarke and Ratika Kumar
    Citation: Respiratory Research 2023 24:15
  25. The CaReQoL Asthma assesses the care-related quality of life outcomes of pulmonary rehabilitation retrospectively in patients with severe asthma. The questionnaire comprises five domains (physical functioning;...

    Authors: Linda Springvloet, Mattanja Triemstra, Bart Knottnerus, Marlon Rolink, Harry Heijerman and Dolf de Boer
    Citation: Respiratory Research 2023 24:14
  26. Pulmonary hypoperfusion is common in children with congenital heart diseases (CHDs) or pulmonary hypertension (PH) and causes adult pulmonary dysplasia. Systematic reviews have shown that some children with CH...

    Authors: Debao Li, Jing Wang, Yuan Fang, Yuqing Hu, Yingying Xiao, Qing Cui, Chuan Jiang, Sijuan Sun, Hao Chen, Lincai Ye and Qi Sun
    Citation: Respiratory Research 2023 24:12
  27. Diabetes mellitus (DM) is a major risk factor for tuberculosis (TB). Evidence has linked the DM-related dysbiosis of gut microbiota to modifiable host immunity to Mycobacterium tuberculosis infection. However, th...

    Authors: Hung-Ling Huang, Yong-Chun Luo, Po-Liang Lu, Cheng-Hsieh Huang, Kun-Der Lin, Meng-Rui Lee, Meng-Hsuan Cheng, Yao-Tsung Yeh, Cheng-Yuan Kao, Jann-Yuan Wang, Jinn-Moon Yang and Inn-Wen Chong
    Citation: Respiratory Research 2023 24:11
  28. Due to the high transmissibility of SARS-CoV-2, accurate diagnosis is essential for effective infection control, but the gold standard, real-time reverse transcriptase-polymerase chain reaction (RT-PCR), is co...

    Authors: Eman Quraishi, Chiamaka Jibuaku, Daniil Lisik, Göran Wennergren, Jan Lötvall, Fredrik Nyberg, Linda Ekerljung, Madeleine Rådinger, Hannu Kankaanranta and Bright I. Nwaru
    Citation: Respiratory Research 2023 24:10
  29. We investigated the effects of vegetable glycerin (VG), a main e-cigarette constituent, on endotoxin-induced acute lung injury (ALI). Mice received intratracheal administration of 30% VG in phosphate buffered ...

    Authors: Vincent Yi-Fong Su, Wei-Chih Chen, Wen-Kuang Yu, Huai-Hsuan Wu, Hao Chen and Kuang-Yao Yang
    Citation: Respiratory Research 2023 24:9
  30. Lung fibroblast activation is associated with airway remodeling during asthma progression. Stearoyl-CoA desaturase 1 (SCD1) plays an important role in the response of fibroblasts to growth factors. This study ...

    Authors: Zili Zhou, Shixiu Liang, Zicong Zhou, Jieyi Liu, Jinming Zhang, Xiaojing Meng, Fei Zou, Haijin Zhao, Changhui Yu and Shaoxi Cai
    Citation: Respiratory Research 2023 24:8
  31. Several observational studies have found that idiopathic pulmonary fibrosis (IPF) is often accompanied by elevated circulating C-reactive protein (CRP) levels. However, the causal relationship between them rem...

    Authors: Kun Zhang, Anqi Li, Jiejun Zhou, Chaoguo Zhang and Mingwei Chen
    Citation: Respiratory Research 2023 24:7
  32. Systemic sclerosis (SSc) is a rare, complex, connective tissue disorder. Interstitial lung disease (ILD) is common in SSc, occurring in 35–52% of patients and accounting for 20–40% of mortality. Evolution of t...

    Authors: Franck F. Rahaghi, Vivien M. Hsu, Robert J. Kaner, Maureen D. Mayes, Ivan O. Rosas, Rajan Saggar, Virginia D. Steen, Mary E. Strek, Elana J. Bernstein, Nitin Bhatt, Flavia V. Castelino, Lorinda Chung, Robyn T. Domsic, Kevin R. Flaherty, Nishant Gupta, Bashar Kahaleh…
    Citation: Respiratory Research 2023 24:6
  33. Previous studies have revealed that sodium-restricted diet intervention significantly decreased apnea frequency among patients with sleep apnea. However, the longitudinal association between the habit of addin...

    Authors: Tingting Li, Lin Song, Guang Li, Fengping Li, Xiaoge Wang, Liangkai Chen, Shuang Rong and Li Zhang
    Citation: Respiratory Research 2023 24:5
  34. Authors: Yuqin Chen, Dansha Zhou, Mingmei Xiong, Xin Xi, Wenni Zhang, Ruifeng Zhang, Lishi Chen, Qian Jiang, Ning Lai, Xiang Li, Jieer Luo, Xuanyi Li, Weici Feng, Chuhui Gao, Jiyuan Chen, Xin Fu…
    Citation: Respiratory Research 2023 24:4

    The original article was published in Respiratory Research 2022 23:314

  35. Allergic asthma is associated with airflow obstruction and hyper-responsiveness that arises from airway inflammation and remodeling. Cell therapy with mesenchymal stem cells (MSC) has been shown to attenuate i...

    Authors: Elga Bandeira, Su Chul Jang, Cecilia Lässer, Kristina Johansson, Madeleine Rådinger and Kyong-Su Park
    Citation: Respiratory Research 2023 24:3
  36. There is an interest in the role of blood eosinophils for predicting inhaled corticosteroid (ICS) response in chronic obstructive pulmonary disease (COPD). Most data are from interventional clinical studies; d...

    Authors: Heinrich Worth, Roland Buhl, Carl-Peter Criée, Peter Kardos, Eva Gückel and Claus F. Vogelmeier
    Citation: Respiratory Research 2023 24:2
  37. Almitrine, a selective pulmonary vasoconstrictor in hypoxic area, improves oxygenation in mechanically ventilated patients with COVID-19 but its effects in spontaneously breathing patients with COVID-19 remain...

    Authors: Clément Saccheri, Lucas Morand, Marie Juston, Denis Doyen, Hervé Hyvernat, Romain Lombardi, Raphaël Devanlay, Émilie Panicucci, Jean Dellamonica and Mathieu Jozwiak
    Citation: Respiratory Research 2023 24:1
  38. Airway fibrosis is one of the pathological characteristics of severe asthma. Transforming growth factor (TGF)-β has been known to promote epithelial-mesenchymal transition formation and to play a role in the p...

    Authors: Wun-Hao Cheng, Shih-Ya Kao, Chia-Ling Chen, Fara Silvia Yuliani, Lee-Yuan Lin, Chien-Huang Lin and Bing-Chang Chen
    Citation: Respiratory Research 2022 23:381
  39. Chronic obstructive pulmonary disease (COPD) is a progressive disorder that causes airway obstruction and lung inflammation. The first-line treatment of COPD is the bronchodilators of β2-agonists and antimusca...

    Authors: Di Liu, Wen Xu, Yuan Tang, Jingxue Cao, Ran Chen, Dingwei Wu, Hongpeng Chen, Bo Su and Jinfu Xu
    Citation: Respiratory Research 2022 23:380
  40. The interest in non-intubated video-assisted thoracic surgery (NIVATS) has risen over the last decade and numerous terms have been used to describe this technique. They all have in common, that the surgical pr...

    Authors: Matthias Grott, Martin Eichhorn, Florian Eichhorn, Werner Schmidt, Michael Kreuter and Hauke Winter
    Citation: Respiratory Research 2022 23:379
  41. Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive interstitial lung disease that has no cure. Many current research efforts center on diagnostic and therapeutic modalities for IPF while other risk ...

    Authors: Aleksandr Kalininskiy, Ashley Rose Rackow, David Nagel, Daniel Croft, Heather McGrane-Minton and Robert Matthew Kottmann
    Citation: Respiratory Research 2022 23:377
  42. Non-tuberculous mycobacterial pulmonary disease (NTM-PD) poses a substantial patient, healthcare, and economic burden. Managing NTM-PD remains challenging, and factors contributing to this include morphologica...

    Authors: Roald van der Laan, Andy Snabilié and Marko Obradovic
    Citation: Respiratory Research 2022 23:376
  43. We recently reported in the phase 3 PANAMO trial that selectively blocking complement 5a (C5a) with vilobelimab led to improved survival in critically ill COVID-19 patients. C5a is an important contributor to ...

    Authors: Endry H. T. Lim, Alexander P. J. Vlaar, Lieuwe D. J. Bos, Lonneke A. van Vught, Anita M. Tuip-de Boer, Romein W. G. Dujardin, Maria Habel, Zhongli Xu, Matthijs C. Brouwer, Diederik van de Beek and Sanne de Bruin
    Citation: Respiratory Research 2022 23:375

Annual Journal Metrics