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  1. Although some studies have indicated that Psoriasis could contribute to the risk of idiopathic pulmonary fibrosis (IPF), no study has reported a clear causal association between them. Our aim was to explore th...

    Authors: Lingli Chen, Yujie Wei, Mengjin Hu, Yile Liu and Xiangrong Zheng
    Citation: Respiratory Research 2024 25:101
  2. Acute lung injury (ALI) and its more severe form, acute respiratory distress syndrome (ARDS) as common life-threatening lung diseases with high mortality rates are mostly associated with acute and severe infla...

    Authors: Xingxing Hu, Menglin Zou, Weishuai Zheng, Minghui Zhu, Qinhui Hou, Han Gao, Xin Zhang, Yuan Liu and Zhenshun Cheng
    Citation: Respiratory Research 2024 25:100
  3. Intra-breath oscillometry has been proposed as a sensitive means of detecting airway obstruction in young children. We aimed to assess the impact of early life wheezing and lower respiratory tract illness on l...

    Authors: Valérie Siroux, Anne Boudier, Sarah Lyon-Caen, Joane Quentin, Yoann Gioria, Zoltán Hantos, Rémy Slama, Isabelle Pin and Sam Bayat
    Citation: Respiratory Research 2024 25:99
  4. COVID-19 is an abnormal host response to the SARS-CoV-2 infection, which is associated with endothelial dysfunction and multi-organ failure. Atorvastatin has been proposed to reduce COVID-19 severity and morta...

    Authors: Naglaa Hamdi Eltahan, Neamat Hamdy Elsawy, Kholoud M. Abdelaaty, Amal Salah Elhamaky, Ahmed H. Hassan and Moataz Maher Emara
    Citation: Respiratory Research 2024 25:97
  5. Solid nodules (SN) had more aggressive features and a poorer prognosis than part-solid nodules (PSN). This study aimed to evaluate the specific impacts of nodule radiological appearance (SN vs. PSN) on lymph n...

    Authors: Zhihua Li, Cheng Pan, Wenzheng Xu, Chen Zhao, Xianglong Pan, Zhibo Wang, Weibing Wu and Liang Chen
    Citation: Respiratory Research 2024 25:96
  6. COVID-19 patients with preexisting interstitial lung disease (ILD) were reported to have a high mortality rate; however, this was based on data from the early stages of the pandemic. It is uncertain how their ...

    Authors: Koichi Miyashita, Hironao Hozumi, Kazuki Furuhashi, Eiji Nakatani, Yusuke Inoue, Hideki Yasui, Yuzo Suzuki, Masato Karayama, Noriyuki Enomoto, Tomoyuki Fujisawa, Naoki Inui, Toshiyuki Ojima and Takafumi Suda
    Citation: Respiratory Research 2024 25:95
  7. Allergic diseases exert a considerable impact on global health, thus necessitating investigations into their etiology and pathophysiology for devising effective prevention and treatment strategies. This study ...

    Authors: Junhao Tu, Jinyang Wen, Qing Luo, Xin Li, Deyun Wang and Jing Ye
    Citation: Respiratory Research 2024 25:94
  8. Chronic obstructive pulmonary disease (COPD) is a common respiratory disease and represents the third leading cause of death worldwide. This study aimed to investigate miRNA regulation of Receptor for Advanced...

    Authors: Chenli Chang, Ke Huang, Xia Xu, Ruirui Duan, Tao Yu, Xu Chu, Chen Chen, Baicun Li and Ting Yang
    Citation: Respiratory Research 2024 25:93
  9. Interstitial lung disease encompasses a group of rare lung conditions causing inflammation and scarring of lung tissue. The typical method of monitoring disease activity is through pulmonary function tests per...

    Authors: Ryan D. Boente, Sydney Schacht, Rebecca Borton, Joseph Vincent, Lilian Golzarri-Arroyo and Nicholas Rattray
    Citation: Respiratory Research 2024 25:92
  10. Prior studies in patients with chronic obstructive pulmonary disease (COPD) had indicated a potential correlation between cadmium (Cd) exposure and reduction in lung function. Nevertheless, the influence of Cd...

    Authors: Jing Sun, You-Peng Deng, Juan Xu, Feng-Min Zhu, Qi-Yuan He, Min-Min Tang, Ying Liu, Jin Yang, Hong-Yan Liu, Lin Fu and Hui Zhao
    Citation: Respiratory Research 2024 25:91
  11. Exposure to PM2.5 has been implicated in a range of detrimental health effects, particularly affecting the respiratory system. However, the precise underlying mechanisms remain elusive.

    Authors: Li Luo, Manling Jiang, Ying Xiong, Anying Xiong, Lei Zhang, Dehong Wu, Yao Liu, Qin Ran, Jiliu Liu, Yi Zhang, Jiahuan Li, Xiang He, Junyi Wang and Guoping Li
    Citation: Respiratory Research 2024 25:90
  12. The morbidity and mortality among hospital inpatients with AECOPD and CVDs remains unacceptably high. Currently, no risk score for predicting mortality has been specifically developed in patients with AECOPD a...

    Authors: Jiarui Zhang, Qun Yi, Chen Zhou, Yuanming Luo, Hailong Wei, Huiqing Ge, Huiguo Liu, Jianchu Zhang, Xianhua Li, Xiufang Xie, Pinhua Pan, Mengqiu Yi, Lina Cheng, Hui Zhou, Liang Liu, Adila Aili…
    Citation: Respiratory Research 2024 25:89
  13. Long-term outcomes of lung transplantation (LTx) remain hampered by chronic lung allograft dysfunction (CLAD). Matrix metalloproteinase 9 (MMP-9) is a secretory endopeptidase identified as a key mediator in fi...

    Authors: Adrien Tissot, Eugénie Durand, Thomas Goronflot, Benjamin Coiffard, Benjamin Renaud-Picard, Antoine Roux, Xavier Demant, Jean-François Mornex, Loïc Falque, Mathilde Salpin, Jérôme Le Pavec, Thomas Villeneuve, Véronique Boussaud, Christiane Knoop, Antoine Magnan, David Lair…
    Citation: Respiratory Research 2024 25:88
  14. After a fortuitous observation of two cases of chemosensitivity recovery in women with congenital central hypoventilation syndrome (CCHS) who took desogestrel, we aimed to evaluate the ventilatory response to ...

    Authors: Caroline Sevoz-Couche, Maxime Patout, Beny Charbit, Thomas Similowski and Christian Straus
    Citation: Respiratory Research 2024 25:87
  15. Bronchopulmonary Dysplasia (BPD) in infants born prematurely is a risk factor for chronic airway obstruction later in life. The distribution of T cell subtypes in the large airways is largely unknown.

    Authors: Jing Gao, Petra Um-Bergström, Melvin Pourbazargan, Eva Berggren-Broström, ChuanXing Li, Heta Merikallio, Riitta Kaarteenaho, Nichole Stacey Reinke, Craig E Wheelock, Erik Melén, Lindén Anders, Åsa M Wheelock, Georgios Rassidakis, Cristian Ortiz-Villalon and Magnus Carl Sköld
    Citation: Respiratory Research 2024 25:86
  16. Chronic obstructive pulmonary disease (COPD) and asthma associate with high morbidity and mortality. High levels of advanced glycation end products (AGEs) were found in tissue and plasma of COPD patients but t...

    Authors: Tianqi Lu, Lies Lahousse, Sara Wijnant, Jinluan Chen, Guy G. Brusselle, Mandy van Hoek and M. Carola Zillikens
    Citation: Respiratory Research 2024 25:85
  17. Post COVID-19 syndrome is characterized by several cardiorespiratory symptoms but the origin of patients’ reported symptomatology is still unclear.

    Authors: Piergiuseppe Agostoni, Massimo Mapelli, Elisabetta Salvioni, Irene Mattavelli, Cristina Banfi, Alice Bonomi, Maria Luisa Biondi, Sara Rovai, Gloria Tamborini, Manuela Muratori, Sarah Ghulam Ali, Stefania Ghilardi, Fabiana De Martino, Carlo Vignati, Pietro Palermo, Paola Gugliandolo…
    Citation: Respiratory Research 2024 25:82
  18. Idiopathic pulmonary fibrosis (IPF) is a progressive disease associated with high mortality. Low muscle mass, frailty and sarcopenia lead to functional impairment that negatively impact quality of life and sur...

    Authors: Meenakshi Sridhar, Sandeep Bodduluri, Lanier O’Hare, Scott Blumhoff, Maria del Pilar Acosta Lara, Joao A. de Andrade, Young-Il Kim, Tracy Luckhardt, MerryLynn McDonald and Tejaswini Kulkarni
    Citation: Respiratory Research 2024 25:81
  19. The latest European Society of Cardiology and European Respiratory Society guidelines have changed the definition of both pre-capillary pulmonary hypertension (PH) and severe PH in chronic lung disease. The cl...

    Authors: Shameek K. Gayen, Mary Zulty and Gerard J. Criner
    Citation: Respiratory Research 2024 25:79
  20. Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with limited treatment options. Circular RNAs (circRNAs) have emerged as a novel class of non-coding RNAs with diverse functions in c...

    Authors: Akshaya Surendran, Chaoqun Huang and Lin Liu
    Citation: Respiratory Research 2024 25:77
  21. Asthma is a heterogeneous disease characterized by airway inflammation and remodeling, whose pathogenetic complexity was associated with abnormal responses of various cell types in the lung. The specific inter...

    Authors: Xiu Yu, Lifei Li, Bicheng Cai, Wei Zhang, Quan Liu, Nan Li, Xing Shi, Li Yu, Rongchang Chen and Chen Qiu
    Citation: Respiratory Research 2024 25:76
  22. Electronic cigarettes (EC) have gained popularity, especially among young people, with the introduction of fourth-generation devices based on e-liquids containing nicotine salts that promise a smoother vaping ...

    Authors: Clément Mercier, Jérémie Pourchez, Lara Leclerc and Valérie Forest
    Citation: Respiratory Research 2024 25:75
  23. DNA methylation regulators (DMRs) play a key role in DNA methylation, thus mediating tumor occurrence, metastasis, and immunomodulation. However, the effects of DMRs on clinical outcomes and immunotherapy resp...

    Authors: Jing Huang, Chujian Huang, Can Huang, Zichang Xiang, Yao Ni, Jian Zeng and Songhua Cai
    Citation: Respiratory Research 2024 25:74
  24. Pneumocystis pneumonia (PCP) is a life-threatening opportunistic fungal infection with a high mortality rate in immunocompromised patients, ranging from 20 to 80%. However, current understanding of the variation ...

    Authors: Hu-Qin Yang, Han Sun, Kang Li, Ming-Ming Shao, Kan Zhai and Zhao-Hui Tong
    Citation: Respiratory Research 2024 25:72
  25. Since the worldwide spread of SARS-CoV-2, different strategies have been followed to combat the pandemic and limit virus transmission. In the meantime, other respiratory viruses continued to circulate, though ...

    Authors: Jaqueline Rhoden, Andressa Taíz Hoffmann, Janaína Franciele Stein, Bruna Seixas da Rocha, Vinícius Monteagudo de Barros, Eduardo Viegas da Silva, Juliane Deise Fleck and Caroline Rigotto
    Citation: Respiratory Research 2024 25:71
  26. Currently, there are no reliable clinical tools that allow non-invasive therapeutic support for patients with pulmonary arterial hypertension. This study aims to propose a low-frequency ultrasound device for p...

    Authors: Vytautas Ostasevicius, Vytautas Jurenas, Mantas Venslauskas, Laura Kizauskiene, Vilma Zigmantaite, Edgaras Stankevicius, Algimantas Bubulis, Joris Vezys and Sandra Mikuckyte
    Citation: Respiratory Research 2024 25:70
  27. Although multidrug-resistant bacteria (MDR) are common in patients undergoing prolonged weaning, there is little data on their impact on weaning and patient outcomes.

    Authors: Julia D. Michels-Zetsche, Vicky Gassmann, Jasmin K. Jasuja, Benjamin Neetz, Philipp Höger, Jan Meis, Simone Britsch, Urte Sommerwerck, Sebastian Fähndrich, Florian Bornitz, Michael M. Müller, Felix J.F. Herth and Franziska C. Trudzinski
    Citation: Respiratory Research 2024 25:69
  28. Metagenomic next-generation sequencing (mNGS), as an emerging technique for pathogen detection, has been widely used in clinic. However, reports on the application of mNGS in cancer patients with severe pneumo...

    Authors: Chao Wang, Xiaojuan Yin, Wenqing Ma, Li Zhao, Xuhong Wu, Nan Ma, Yuepeng Cao, Quanli Zhang, Shuliang Ma, Lin Xu and Xuerong Wang
    Citation: Respiratory Research 2024 25:68
  29. Chronic obstructive pulmonary disease (COPD) is a leading aging related cause of global mortality. Small airway narrowing is recognized as an early and significant factor for COPD development. Senescent fibrob...

    Authors: Fang Lu, Li-peng Yao, Dan-dan Gao, Tahereh Alinejad, Xin-qing Jiang, Qi Wu, Qiao-cheng Zhai, Ming Liu, Sheng-mei Zhu, Mao-xiang Qian, Li-feng Xu, Cheng-shui Chen and Feng Zhang
    Citation: Respiratory Research 2024 25:67
  30. Small airway remodelling is a vital characteristic of chronic obstructive pulmonary disease (COPD), which is mainly caused by epithelial barrier dysfunction and epithelial-mesenchymal transition (EMT). Recent ...

    Authors: Qin Zhang, Liming Yan, Ye Lu, Xiaodong Liu, Yan Yin, Qiuyue Wang, Xiu Gu and Xiaoming Zhou
    Citation: Respiratory Research 2024 25:66
  31. Endobronchial ultrasound (EBUS) and cone-beam computed tomography-derived augmented fluoroscopy (CBCT-AF) are utilized for the diagnosis of peripheral pulmonary lesions (PPLs). Combining them with transbronchi...

    Authors: Ching-Kai Lin, Sheng-Yuan Ruan, Hung-Jen Fan, Hao-Chun Chang, Yen-Ting Lin and Chao-Chi Ho
    Citation: Respiratory Research 2024 25:65
  32. Among patients with chronic obstructive pulmonary disease (COPD), some have features of both asthma and COPD—a condition categorized as asthma-COPD overlap (ACO). Our aim was to determine whether asthma- or CO...

    Authors: Yu-Ping Chang, Yi-Hsuan Tsai, Yu-Mu Chen, Kuo-Tung Huang, Chiu-Ping Lee, Po-Yuan Hsu, Hung-Chen Chen, Meng-Chih Lin and Yung-Che Chen
    Citation: Respiratory Research 2024 25:64
  33. Peripheral blood oxygen monitoring via chemoreceptors in the carotid body (CB) is an integral function of the autonomic cardiorespiratory regulation. The presence of the purinergic P2Y12 receptor (P2Y12R) has ...

    Authors: András Iring, Mária Baranyi, Bernadett Iring-Varga, Paula Mut-Arbona, Zsuzsanna T. Gál, Dorina Nagy, László Hricisák, János Varga, Zoltán Benyó and Beáta Sperlágh
    Citation: Respiratory Research 2024 25:61
  34. Long-term invasive mechanical ventilation (IMV) is a major burden for those affected and causes high costs for the health care system. Early risk assessment is a prerequisite for the best possible support of h...

    Authors: Franziska C. Trudzinski, Julia D. Michels-Zetsche, Benjamin Neetz, Jan Meis, Michael Müller, Axel Kempa, Claus Neurohr, Armin Schneider, Felix J. F. Herth, Joachim Szecsenyi, Elena Biehler, Thomas Fleischauer, Michel Wensing, Simone Britsch, Janina Schubert-Haack, Thomas Grobe…
    Citation: Respiratory Research 2024 25:60
  35. Non-small cell lung cancer (NSCLC) accounts for the vast majority of lung cancers. Early detection is crucial to reduce lung cancer-related mortality. Aberrant DNA methylation occurs early during carcinogenesi...

    Authors: Yunhui Qu, Xiuzhi Zhang, Rong Qiao, Feifei Di, Yakang Song, Jun Wang, Longtao Ji, Jie Zhang, Wanjian Gu, Yifei Fang, Baohui Han, Rongxi Yang, Liping Dai and Songyun Ouyang
    Citation: Respiratory Research 2024 25:59
  36. The circulating metabolome, reflecting underlying cellular processes and disease biology, has not been fully characterized in patients with idiopathic pulmonary fibrosis (IPF). We evaluated whether circulating...

    Authors: Ross Summer, Jamie L. Todd, Megan L. Neely, L. Jason Lobo, Andrew Namen, L. Kristin Newby, Shirin Shafazand, Sally Suliman, Christian Hesslinger, Sascha Keller, Thomas B. Leonard, Scott M. Palmer, Olga Ilkayeva, Michael J. Muehlbauer, Christopher B. Newgard and Jesse Roman
    Citation: Respiratory Research 2024 25:58
  37. Lymphangioleiomyomatosis (LAM) is a rare disease which is easily misdiagnosed. Vascular endothelial growth factor D (VEGF-D), as the most common biomarker, however, is not so perfect for the diagnosis and seve...

    Authors: Xixi Song, Hui Cai, Wenjun Peng, Ke Chen, Zilinuer Abuduxukuer, Yingying Zeng, Guiping Zhu, Chong Lu, Yu Chen, Jian Wang, Ling Ye and Meiling Jin
    Citation: Respiratory Research 2024 25:57
  38. MRproANP and COPAVP are prognostic markers for mortality in chronic obstructive pulmonary disease (COPD). Furthermore, these biomarkers predict mortality due to cardiovascular diseases, which are important pro...

    Authors: S. Fähndrich, C. Herr, S. Teuteberg, P. Alter, S. Söhler, D. Soriano, J. Classen, J. Adams, V. Weinhold, H. Watz, B. Waschki, T. Zeller, M. Eichenlaub, F. C. Trudzinski, J. D. Michels, A. Omlor…
    Citation: Respiratory Research 2024 25:56
  39. Alveolar hypercoagulation and fibrinolytic inhibition are mainly responsible for massive alveolar fibrin deposition, which are closely related with refractory hypoxemia in acute respiratory distress syndrome (...

    Authors: Chuan Xiao, Jiaoyangzi Liu, Yumei Cheng, Yingxia Wu, Qing Li, Xianjun Chen, Jia Yuan, Qi Dong, Lu Li, Ying liu and Feng Shen
    Citation: Respiratory Research 2024 25:54
  40. Computed tomography (CT) scan is commonly performed for pleural effusion diagnostis in the clinic. However, there are limited data assessing the accuracy of thoracic CT for the separation of transudative from ...

    Authors: Yan Zhang, Yang Zhang, Wei Wang, Xiaoyu Feng, Jiahuan Guo, Bo Chen, Fuyun Zhang, Huanhuan Wang, Mengnan Fan, Yingwei Zhu, Yuxia Sun, Tongsheng Wang, Yimin Mao and Pengfei Gao
    Citation: Respiratory Research 2024 25:53
  41. Mucus plugs have been described in the airways of asthmatic subjects, particularly those with associated with type 2 inflammation and sputum eosinophilia. In the current study we addressed the question of whet...

    Authors: Camille Audousset, Sana Swaleh, Ron Olivenstein, Motahareh Vameghestahbanati, Miranda Kirby, Alexandre Semionov, Benjamin M. Smith and James G. Martin
    Citation: Respiratory Research 2024 25:52

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