Featured article:From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function
Genetic and environmental factors play a role in the development of COPD. The epigenome, and more specifically DNA methylation, is recognized as important link between these factors. The authors postulate that DNA methylation is one of the routes by which cigarette smoke influences the development of COPD. In this study, the authors aim aim to identify CpG-sites that are associated with cigarette smoke exposure and lung function levels in whole blood and validate these CpG-sites in lung tissue.
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Respiratory Research publishes high-quality clinical and basic research, review and commentary articles on all aspects of respiratory medicine and related diseases.
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Oliver Schildgen, Kliniken der Stadt Koln gGmbH, Klinikum der Privaten Universitat Witten/Herdecke, Germany
Kelan Tantisira, Brigham and Women's Hospital, USA
Robert Bals, Saarland University, Germany
Francesco Blasi, University of Milan, Italy
Arnaud Bourdin, University of Montpellier, France
Mario Cazzola, University of Rome Tor Vergata, Italy
Sanjay Haresh Chotirmall, Lee Kong Chian School of Medicine, Singapore
Suzanne Cloonan, Weill Cornell Medicine, USA
Taylor Cohen, MedImmune, USA
Bruno Crestani, Bichat Hospital, France
Jeanine D'Armiento, Columbia University College of Physicians and Surgeons, USA
Olivier Danhaive, University of California San Francisco, USA
Massimo Di Maio, University of Turin, Italy
Louise Donnelly, Imperial College London, UK
Michael Kreuter, Universitatsklinikum Heidelberg, Germany
Guha Krishnaswamy, Wake Baptist Hospital, USA
Victor Laubach, University of Virginia, USA
Yasuhiko Nishioka, Tokushima University, Japan
Stylianos Orfanos, National and Kapodistrian University of Athens, Greece
Reynold A. Panettieri Jr, Rutgers, The State University of New Jersey, USA
Stephen Peters, Wake Forest University Health Sciences, USA
YS Prakash, Mayo Clinic, USA
Giovanni Sotgiu, University of Sassari, Italy
Dale D Tang, Albany Medical College, USA
Johan Verbraecken, Antwerp University Hospital, Belgium
Professor at the Department of Internal Medicine, and Chairman of the Krefting Research Centre at the University of Gothenburg.
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