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Featured article: Distinct COPD subtypes in former smokers revealed by gene network perturbation analysis

New Content Item (1)Chronic obstructive pulmonary disease (COPD) varies significantly in symptomatic and physiologic presentation. Identifying disease subtypes from molecular data, collected from easily accessible blood samples, can help stratify patients and guide disease management and treatment. In this study, the authors use the ssNPA method on blood gene expression data to identify and validate four clusters of former smokers with COPD, which correspond to clinically relevant disease subtypes, reflecting differences in severity, symptoms and mortality.

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Electronic cigarettes: Investigating the harms and benefits

Guest edited by Associate Editor, Professor Robert Bals (Saarland University, Germany), this series of articles provides newest research and comprehensive background information on e-cigarettes. The articles aim to address the needs of basic researchers, clinicians and other individuals that need up-to-data information on this topic.

Respiratory Research is pleased to still be accepting submissions for this thematic series.


About the Editors

Robert Bals

​​​​Prof. Bals is the director of the Saarland University’s Department of Pulmonology, where Prof. Bals focuses on teaching, research, and patient care. In the research area, Prof. Bals covers preclinical and clinical research and has contributed to 250 papers and several books. His research areas are inflammatory lung disease, asthma, COPD, and infection. In the basic science laboratory, Prof. Bals and his team investigate the mechanisms how the lung interacts with the environment including smoke, allergens, and microorganisms with a focus on stem cell biology and regeneration. In clinical research, he performs investigations in COPD, asthma, pneumonia and cystic fibrosis. He established and manages the German alpha-1-antitrypsin registry and is member of the steering committee of COSYCONET.

New Content ItemDale Tang

Prof. Tang is a Professor of the Department of Molecular and Cellular Physiology at Albany Medical College, New York, United States of America. He is Director of Cytoskeletal Signaling and Asthma Research Program at the school. His research is involved in asthma, pulmonary arterial hypertension, lung inflammation, smooth muscle biochemistry, physiology and molecular biology. His research has been funded by multiple NIH grants and other funding agencies. 

Submit your review

Respiratory Research welcomes review articles on a variety of different topics relating to the scope of the journal. Submit your review today.

For further queries or to discuss the limited funds which may be available to cover the article-processing charge, please contact the editorial team.

Aims and scope

Respiratory Research publishes high-quality clinical and basic research, review and commentary articles on all aspects of respiratory medicine and related diseases.

As the leading fully open access journal in the field, Respiratory Research provides an essential resource for pulmonologists, allergists, immunologists and other physicians, researchers, healthcare workers and medical students with worldwide dissemination of articles resulting in high visibility and generating international discussion.

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Editorial board

Robert Bals, Saarland University, Germany
Dale D. Tang, Albany Medical College, USA

Associate Editors
Tiago Alfaro, University of Coimbra, Portugal
Steven An, Rutgers University, USA
Takuya Aoki, Tokai University School of Medicine, Japan
Cristina Ardura-Garcia, University of Bern, Switzerland
Francesco Blasi, University of Milan, Italy
Su Bo, Shanghai Pulmonary Hospital, China
Agnes Boots, Maastricht University, Netherlands
Arnaud Bourdin, University of Montpellier, France
Mario Cazzola, University of Rome Tor Vergata, Italy
Kuei-Pin Chung, National Taiwan University College of Medicine, Taiwan
Suzanne Cloonan, Weill Cornell Medicine, USA
Taylor Cohen, MedImmune, USA
Jeanine D'Armiento, Columbia University College of Physicians and Surgeons, USA
Olivier Danhaive, University of California San Francisco, USA
Rafael E. de la Hoz, Icahn School of Medicine at Mount Sinai, USA
Sara De Matteis, Imperial College London, UK
Deepak Deshpande, Thomas Jefferson University, USA
Marta Drummond, University of Porto, Portugal
Orianne Dumas, Inserm, France
Elaine Fuertes, Imperial College London, UK
Eric Garshick, VA Boston Healthcare System, USA
Jose Gomez Villalobos, Yale University, USA
Andrea Gramegna, University of Milan, Italy
Kathleen Haley, Brigham and Women's Hospital, USA
Qinghua Hu, Huazhong Science and Technology University, Tongji Medical College, China
Marco Idzko, Medical University of Vienna, Austria
Dany Jaffuel, Regional University Hospital of Montpellier, France
Riitta Kaarteenaho, Oulu University Hospital, Finland
Victor Laubach, University of Virginia, USA
Anna Lavizzari, Fondazione IRCCS Ca' Grande Ospedale Maggiore Policlinico, Italy
Mareike Lehmann, Helmholtz Center Munich, Germany
Micheal Mac Aogain, St. James's Hospital and Trinity College Dublin, Ireland
Arnaud Mailleux, INSERM, France
Federico Mei, Polytechnic University of Marche, Italy
Nobuaki Miyahara, Okayama University, Japan 
Yasuhiko Nishioka, Tokushima University, Japan
Stylianos Orfanos, National and Kapodistrian University of Athens, Greece
Victor Ortega, Wake Forest School of Medicine, USA
Bi-Yun Qian, Shanghai Jiao Tong University, China
Giacomo Sgalla, Fondazione Policlinico Universitario A.Gemelli IRCCS, Italy
Ilias Siempos, Weill Cornell Medicine, USA
Sunit Singh, Banaras Hindu University, India
Hortense Slevogt, Jena University Hospital, Germany
Giovanni Sotgiu, University of Sassari, Italy
Pei Yee Tiew, Singapore General Hospital, Singapore
David Tingay, The Royal Children's Hospital, Australia
Sara Tomassetti, Careggi Hospital, Italy
Argyris Tzouvelekis, University of Patras, Greece
Niki Ubags, Centre Hospitalier Universitaire Vaudois, Switzerland
Johan Verbraecken, Antwerp University Hospital, Belgium
Tao Wang, Huazhong University of Science and Technology, China
Xiaobo Zhou, Brigham and Women's Hospital, USA

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