Featured article:From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function
Genetic and environmental factors play a role in the development of COPD. The epigenome, and more specifically DNA methylation, is recognized as important link between these factors. The authors postulate that DNA methylation is one of the routes by which cigarette smoke influences the development of COPD. In this study, the authors aim aim to identify CpG-sites that are associated with cigarette smoke exposure and lung function levels in whole blood and validate these CpG-sites in lung tissue.
About the Editors
Dr. Kelan Tantisira, of the Brigham and Women’s Hospital and Harvard Medical School, has directed seminal studies in respiratory epidemiology, genomics, and pharmacogenomics, as well as in the fetal genomic orgins of lung disease. His work focuses primarily on factors influencing asthma susceptibility, severity, prognosis, and treatment response, with particular interests in asthma pharmacogenomics, translational genomics, and personalized, prognostic medicine.
Oliver Schildgen is professor for Virology at the Private University of Witten/Herdecke and Head of the Molecular Pathology laboratory at the Institute for Pathology at the Community Hospital of the City of Cologne, Germany. Besides his work on newly detected respiratory viruses, with major focus on the human bocavirus, Prof. Schildgen’s research interests are culturing of P. jirovecii, lung cancer epidemiology with focus on therapy-relevant mutations patterns, and development of novel diagnostic assays.
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Aims and scope
Respiratory Research publishes high-quality clinical and basic research, review and commentary articles on all aspects of respiratory medicine and related diseases.
As the leading fully open access journal in the field, Respiratory Research provides an essential resource for pulmonologists, allergists, immunologists and other physicians, researchers, healthcare workers and medical students with worldwide dissemination of articles resulting in high visibility and generating international discussion.
Oliver Schildgen, Kliniken der Stadt Koln gGmbH, Klinikum der Privaten Universitat Witten/Herdecke, Germany
Kelan Tantisira, Brigham and Women's Hospital, USA
Robert Bals, Saarland University, Germany
Francesco Blasi, University of Milan, Italy
Arnaud Bourdin, University of Montpellier, France
Mario Cazzola, University of Rome Tor Vergata, Italy
Sanjay Haresh Chotirmall, Lee Kong Chian School of Medicine, Singapore
Suzanne Cloonan, Weill Cornell Medicine, USA
Taylor Cohen, MedImmune, USA
Bruno Crestani, Bichat Hospital, France
Jeanine D'Armiento, Columbia University College of Physicians and Surgeons, USA
Olivier Danhaive, University of California San Francisco, USA
Massimo Di Maio, University of Turin, Italy
Louise Donnelly, Imperial College London, UK
Michael Kreuter, Universitatsklinikum Heidelberg, Germany
Guha Krishnaswamy, Wake Baptist Hospital, USA
Victor Laubach, University of Virginia, USA
Yasuhiko Nishioka, Tokushima University, Japan
Stylianos Orfanos, National and Kapodistrian University of Athens, Greece
Reynold A. Panettieri Jr, Rutgers, The State University of New Jersey, USA
Stephen Peters, Wake Forest University Health Sciences, USA
YS Prakash, Mayo Clinic, USA
Giovanni Sotgiu, University of Sassari, Italy
Dale D Tang, Albany Medical College, USA
Johan Verbraecken, Antwerp University Hospital, Belgium
Marlies Wijsenbeek, Erasmus University Rotterdam, Netherlands
2017 Journal Metrics
45 days to first decision for reviewed manuscripts only
40 days to first decision for all manuscripts
121 days from submission to acceptance
13 days from acceptance to publication
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