Genetic and environmental factors play a role in the development of COPD. The epigenome, and more specifically DNA methylation, is recognized as important link between these factors. The authors postulate that DNA methylation is one of the routes by which cigarette smoke influences the development of COPD. In this study, the authors aim aim to identify CpG-sites that are associated with cigarette smoke exposure and lung function levels in whole blood and validate these CpG-sites in lung tissue.
Guest edited by Associate Editor, Professor Robert Bals (Saarland University, Germany), this series of articles provides newest research and comprehensive background information on e-cigarettes. The articles aim to address the needs of basic researchers, clinicians and other individuals that need up-to-data information on this topic.
Respiratory Research is pleased to still be accepting submissions for this thematic series.
Respiratory illnesses affect hundreds of millions of children worldwide. In this blog, Dr Paul Porter, author of a new study in Respiratory Research, talks about the development of a new tool for diagnosing childhood respiratory disease, using only a smartphone, acoustic analysis, and the power of mathematics.
Featured article: From blood to lung tissue: effect of cigarette smoke on DNA methylation and lung function
About the Editors
Dr. Kelan Tantisira, of the Brigham and Women’s Hospital and Harvard Medical School, has directed seminal studies in respiratory epidemiology, genomics, and pharmacogenomics, as well as in the fetal genomic orgins of lung disease. His work focuses primarily on factors influencing asthma susceptibility, severity, prognosis, and treatment response, with particular interests in asthma pharmacogenomics, translational genomics, and personalized, prognostic medicine.
Oliver Schildgen is professor for Virology at the Private University of Witten/Herdecke and Head of the Molecular Pathology laboratory at the Institute for Pathology at the Community Hospital of the City of Cologne, Germany. Besides his work on newly detected respiratory viruses, with major focus on the human bocavirus, Prof. Schildgen’s research interests are culturing of P. jirovecii, lung cancer epidemiology with focus on therapy-relevant mutations patterns, and development of novel diagnostic assays.
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Aims and scope
Respiratory Research publishes high-quality clinical and basic research, review and commentary articles on all aspects of respiratory medicine and related diseases.
As the leading fully open access journal in the field, Respiratory Research provides an essential resource for pulmonologists, allergists, immunologists and other physicians, researchers, healthcare workers and medical students with worldwide dissemination of articles resulting in high visibility and generating international discussion.
Oliver Schildgen, Kliniken der Stadt Koln gGmbH, Klinikum der Privaten Universitat Witten/Herdecke, Germany
Kelan Tantisira, Brigham and Women's Hospital, USA
Takuya Aoki, Tokai University School of Medicine, Japan
Robert Bals, Saarland University, Germany
Francesco Blasi, University of Milan, Italy
Su Bo, Shanghai Pulmonary Hospital, China
Arnaud Bourdin, University of Montpellier, France
Mario Cazzola, University of Rome Tor Vergata, Italy
Sanjay Haresh Chotirmall, Lee Kong Chian School of Medicine, Singapore
Suzanne Cloonan, Weill Cornell Medicine, USA
Taylor Cohen, MedImmune, USA
Bruno Crestani, Bichat Hospital, France
Jeanine D'Armiento, Columbia University College of Physicians and Surgeons, USA
Olivier Danhaive, University of California San Francisco, USA
Massimo Di Maio, University of Turin, Italy
Louise Donnelly, Imperial College London, UK
Eric Garshick, VA Boston Healthcare System, USA
Michael Kreuter, Universitatsklinikum Heidelberg, Germany
Guha Krishnaswamy, Wake Baptist Hospital, USA
Larry Lands, McGill University, Canada
Victor Laubach, University of Virginia, USA
Yasuhiko Nishioka, Tokushima University, Japan
Stylianos Orfanos, National and Kapodistrian University of Athens, Greece
Reynold A. Panettieri Jr, Rutgers, The State University of New Jersey, USA
Stephen Peters, Wake Forest University Health Sciences, USA
Massimo Pistolesi, University of Florence, Italy
YS Prakash, Mayo Clinic, USA
Jennifer Quint, Imperial College London, UK
Sunit Singh, Banaras Hindu University, India
Giovanni Sotgiu, University of Sassari, Italy
Dale D Tang, Albany Medical College, USA
Johan Verbraecken, Antwerp University Hospital, Belgium
Marlies Wijsenbeek, Erasmus University Rotterdam, Netherlands
Annual Journal Metrics
49 days to first decision for reviewed manuscripts only
44 days to first decision for all manuscripts
107 days from submission to acceptance
18 days from acceptance to publication
2,241 Altmetric mentions