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  1. Sarcoidosis is a systemic granulomatous disease of unknown etiology primarily affecting the lungs. Treatment is needed when disease symptoms worsen and organ function deteriorates. In pulmonary sarcoidosis, pr...

    Authors: Raisa Kraaijvanger, Montse Janssen Bonás, Jan C. Grutters, Ioanna Paspali, Marcel Veltkamp, Dominique P. V. de Kleijn and Coline H. M. van Moorsel
    Citation: Respiratory Research 2024 25:166
  2. Little is known about the relationships between human genetics and the airway microbiome. Deeply sequenced airway metagenomics, by simultaneously characterizing the microbiome and host genetics, provide a uniq...

    Authors: Jingyuan Gao, Yuqiong Yang, Xiaopeng Xiang, Huimin Zheng, Xinzhu Yi, Fengyan Wang, Zhenyu Liang, Dandan Chen, Weijuan Shi, Lingwei Wang, Di Wu, Shengchuan Feng, Qiaoyun Huang, Xueping Li, Wensheng Shu, Rongchang Chen…
    Citation: Respiratory Research 2024 25:165
  3. Balloon pulmonary angioplasty (BPA) improves the prognosis of chronic thromboembolic pulmonary hypertension (CTEPH). Right ventricle (RV) is an important predictor of prognosis in CTEPH patients. 2D-speckle tr...

    Authors: Yaning Ma, Dichen Guo, Jianfeng Wang, Juanni Gong, Huimin Hu, Xinyuan Zhang, Yeqing Wang, Yuanhua Yang, Xiuzhang Lv and Yidan Li
    Citation: Respiratory Research 2024 25:164
  4. Interleukin (IL)-26 is produced by T helper type 17 (Type 17) cells and exerts immunomodulatory plus antimicrobial effects. Previous studies show that local IL-26 concentrations in the airways are higher in pa...

    Authors: Melissa A. Kovach, Ulrika Käck, Karlhans F Che, Bettina Brundin, Jon R. Konradsen and Anders Lindén
    Citation: Respiratory Research 2024 25:163
  5. Remote monitoring of patient-recorded spirometry and pulse oximetry offers an alternative approach to traditional hospital-based monitoring of interstitial lung disease (ILD). Remote spirometry has been observ...

    Authors: Sarah Barth, Colin Edwards, Gauri Saini, Yussef Haider, Nicholas Paul Williams, Will Storrar, Gisli Jenkins, Iain Stewart and Melissa Wickremasinghe
    Citation: Respiratory Research 2024 25:162
  6. Longitudinal studies have identified childhood asthma as a risk factor for obstructive pulmonary disease (COPD) and asthma-COPD overlap (ACO) where persistent airflow limitation can develop more aggressively. ...

    Authors: Nok Him Fung, Quynh Anh Nguyen, Catherine Owczarek, Nick Wilson, Nadeem Elahee Doomun, David De Souza, Kylie Quinn, Stavros Selemidis, Jonathan McQualter, Ross Vlahos, Hao Wang and Steven Bozinovski
    Citation: Respiratory Research 2024 25:161
  7. Light chain deposition disease (LCDD) is a very rare entity. Clinical manifestations of LCDD vary according to the organs involved. Data on pulmonary LCDD are scarce and limited to small series or case reports...

    Authors: François Lestelle, Catherine Beigelman, David Rotzinger, Salim Si-Mohamed, Mouhamad Nasser, Lidwine Wemeau, Sandrine Hirschi, Grégoire Prevot, Antoine Roux, Vincent Bunel, Emmanuel Gomez, Laurent Sohier, Helene Morisse Pradier, Martine Reynaud Gaubert, Anne Gondouin, Romain Lazor…
    Citation: Respiratory Research 2024 25:159
  8. Airway remodelling plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). Epithelial–mesenchymal transition (EMT) is a significant process during the occurrence of airway ...

    Authors: Yu Ding, Ziteng Wang, Zheming Zhang, Rong You, Yan Wu and Tao Bian
    Citation: Respiratory Research 2024 25:158
  9. Environmental/occupational exposures cause significant lung diseases. Agricultural organic dust extracts (ODE) and bacterial component lipopolysaccharide (LPS) induce recruited, transitioning murine lung monoc...

    Authors: Aaron D. Schwab, Todd A. Wyatt, Grace Moravec, Geoffrey M. Thiele, Amy J. Nelson, Angela Gleason, Oliver Schanze, Michael J. Duryee, Debra J. Romberger, Ted R. Mikuls and Jill A. Poole
    Citation: Respiratory Research 2024 25:157
  10. Lung cancers represent the main cause of cancer related-death worldwide. Recently, immunotherapy alone or in combination with chemotherapy has deeply impacted the therapeutic care leading to an improved overal...

    Authors: Pauline Hulo, Sophie Deshayes, Judith Fresquet, Anne-Laure Chéné, Stéphanie Blandin, Nicolas Boisgerault, Jean-François Fonteneau, Lucas Treps, Marc G Denis, Jaafar Bennouna, Delphine Fradin, Elvire Pons-Tostivint and Christophe Blanquart
    Citation: Respiratory Research 2024 25:156
  11. Reference values for lung volumes are necessary to identify and diagnose restrictive lung diseases and hyperinflation, but the values have to be validated in the relevant population. Our aim was to investigate...

    Authors: Tobias Mraz, Shervin Asgari, Ahmad Karimi, Marie-Kathrin Breyer, Sylvia Hartl, Owat Sunanta, Alina Ofenheimer, Otto C. Burghuber, Angela Zacharasiewicz, Bernd Lamprecht, Caspar Schiffers, Emiel F. M. Wouters and Robab Breyer-Kohansal
    Citation: Respiratory Research 2024 25:155
  12. Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fatal, and aging-associated interstitial lung disease with a poor prognosis and limited treatment options, while the pathogenesis remains elusive....

    Authors: Ruyan Wan, Siqi Long, Shuaichen Ma, Peishuo Yan, Zhongzheng Li, Kai Xu, Hui Lian, Wenwen Li, Yudi Duan, Miaomiao Zhu, Lan Wang and Guoying Yu
    Citation: Respiratory Research 2024 25:154
  13. Wnt/β-catenin signaling is critical for lung development and AT2 stem cell maintenance in adults, but excessive pathway activation has been associated with pulmonary fibrosis, both in animal models and human d...

    Authors: Mehaben Patel, Yorick Post, Natalie Hill, Asmiti Sura, Jay Ye, Trevor Fisher, Nicholas Suen, Mengrui Zhang, Leona Cheng, Ariel Pribluda, Hui Chen, Wen-Chen Yeh, Yang Li, Hélène Baribault and Russell B. Fletcher
    Citation: Respiratory Research 2024 25:153
  14. Authors: Afisi S. Ismaila, Kieran J. Rothnie, Robert P. Wood, Victoria L. Banks, Lucinda J. Camidge, Alexandrosz Czira, Chris Compton, Raj Sharma, Shannon N. Millard, Olivia Massey and David M. G. Halpin
    Citation: Respiratory Research 2024 25:152

    The original article was published in Respiratory Research 2023 24:229

  15. EXO-CD24 are exosomes genetically manipulated to over-express Cluster of Differentiation (CD) 24. It consists of two breakthrough technologies: CD24, the drug, as a novel immunomodulator that is smarter than s...

    Authors: Ioannis Grigoropoulos, Georgios Tsioulos, Artemis Kastrissianakis, Shiran Shapira, Orr Green, Vasiliki Rapti, Maria Tsakona, Thomas Konstantinos, Athina Savva, Dimitra Kavatha, Dimitrios Boumpas, Konstantinos Syrigos, Ioannis Xynogalas, Konstantinos Leontis, Vasileios Ntousopoulos, Vissaria Sakka…
    Citation: Respiratory Research 2024 25:151
  16. The association between longitudinal body mass index (BMI) change and clinical outcomes in patients with chronic obstructive pulmonary disease (COPD) has not fully investigated.

    Authors: Taeyun Kim, Sun Hye Shin, Hyunsoo Kim, Yunjoo Im, Juhee Cho, Danbee Kang and Hye Yun Park
    Citation: Respiratory Research 2024 25:150
  17. The clinical significance of the impulse oscillometry-defined small airway bronchodilator response (IOS-BDR) is not well-known. Accordingly, this study investigated the clinical characteristics of IOS-BDR and ...

    Authors: Lifei Lu, Fan Wu, Jieqi Peng, Xiaohui Wu, Xiangqing Hou, Youlan Zheng, Huajing Yang, Zhishan Deng, Cuiqiong Dai, Ningning Zhao, Kunning Zhou, Qi Wan, Gaoying Tang, Jiangyu Cui, Shuqing Yu, Xiangwen Luo…
    Citation: Respiratory Research 2024 25:149
  18. Astaxanthin (AXT) is a keto-carotenoid with a variety of biological functions, including antioxidant and antifibrotic effects. Small airway remodeling is the main pathology of chronic obstructive pulmonary dis...

    Authors: Haidong Ding, Liming Yan, Yu Wang, Ye Lu, Mingming Deng, Yingxi Wang, Qiuyue Wang and Xiaoming Zhou
    Citation: Respiratory Research 2024 25:148
  19. Inflammation and immune processes underlie pulmonary hypertension progression. Two main different activated phenotypes of macrophages, classically activated M1 macrophages and alternatively activated M2 macrop...

    Authors: Yifan Zuo, Boyang Li, Minglang Gao, Rui Xiong, Ruyuan He, Ning Li and Qing Geng
    Citation: Respiratory Research 2024 25:147
  20. In chronic pulmonary diseases characterized by inflammation and airway obstruction, such as asthma and COPD, there are unmet needs for improved treatment. Quinolines is a group of small heterocyclic compounds ...

    Authors: Jesper Bergwik, Jielu Liu, Médea Padra, Ravi K. V. Bhongir, Lloyd Tanner, Yujiao Xiang, Mia Lundblad, Arne Egesten and Mikael Adner
    Citation: Respiratory Research 2024 25:146
  21. Patient experiences with COVID-19 aftercare remain largely unknown. We evaluated COVID-19 aftercare from a patient perspective one year after hospitalization, assessing satisfaction and its associated factors,...

    Authors: Julia C. Berentschot, Willemijn A. de Ridder, L. Martine Bek, Majanka H. Heijenbrok-Kal, Gert-Jan Braunstahl, Sylvia C. Remerie, Yvonne Stuip, Gerard M. Ribbers, Joachim G. J. V. Aerts, Erwin Ista, Merel E. Hellemons and Rita J. G. van den Berg-Emons
    Citation: Respiratory Research 2024 25:145
  22. The aim of this study was to develop a nomogram by combining chest computed tomography (CT) images and clinicopathological predictors to assess the survival outcomes of patients with primary pulmonary lymphoep...

    Authors: Kai Nie, Lin Zhu, Yuxuan Zhang, Yinan Chen, John Parrington and Hong Yu
    Citation: Respiratory Research 2024 25:144
  23. Although ROX index is frequently used to assess the efficacy of high-flow nasal cannula treatment in acute hypoxemic respiratory failure (AHRF) patients, the relationship between the ROX index and the mortalit...

    Authors: Kai Liu, Xin-Yi Ma, Hua Xiao, Wan-Jie Gu, Jun Lyu and Hai-Yan Yin
    Citation: Respiratory Research 2024 25:143
  24. The underlying pathophysiological pathways how reverse triggering is being caused are not fully understood. Respiratory entrainment may be one of these mechanisms, but both terms are used interchangeably. We s...

    Authors: Robert G.T. Blokpoel, Ruben B.R. Brandsema, Alette A. Koopman, Jefta van Dijk and Martin C.J. Kneyber
    Citation: Respiratory Research 2024 25:142
  25. Smoking remains a major risk factor for the development and progression of chronic obstructive pulmonary disease (COPD). Due to the adolescent smoking associated with worse health state, the age, at which an i...

    Authors: Jiankang Wu, Weiwei Meng, Yiming Ma, Zhiqi Zhao, Ruoyan Xiong, Jiayu Wang, Rui Zhao, Huihui Zeng and Yan Chen
    Citation: Respiratory Research 2024 25:140
  26. DEHP, a common plasticizer known for its hormone-disrupting properties, has been associated with asthma. However, a significant proportion of adult asthma cases are “non-atopic”, lacking a clear etiology.

    Authors: Yuan-Ting Hsu, Chao-Chien Wu, Chin-Chou Wang, Chau-Chyun Sheu, Yi-Hsin Yang, Ming-Yen Cheng, Ruay-Sheng Lai, Sum-Yee Leung, Chi-Cheng Lin, Yu-Feng Wei, Yung-Fa Lai, Meng-Hsuan Cheng, Huang-Chi Chen, Chih-Jen Yang, Chien-Jen Wang, Huei-Ju Liu…
    Citation: Respiratory Research 2024 25:139
  27. The prognostic and theragnostic role of histopathological subsets in systemic sclerosis interstitial lung disease (SSc-ILD) have been largely neglected due to the paucity of treatment options and the risks ass...

    Authors: A Damiani, M Orlandi, C Bruni, G Bandini, G Lepri, C Scaletti, C Ravaglia, F Frassanito, S Guiducci, A Moggi-Pignone, M Matucci-Cerinic, V Poletti, L Tofani, TV Colby, S Bellando Randone and Sara Tomassetti
    Citation: Respiratory Research 2024 25:138
  28. Publications utilizing precision cut lung slices (PCLS) steadily increased from the 1970’s, with a significant increase in 2010, to tripling by 2023. PCLS have been used to study a vast array of pulmonary dise...

    Authors: Cynthia J. Koziol-White and Reynold A. Panettieri Jr.
    Citation: Respiratory Research 2024 25:137
  29. Computed tomography (CT) is routinely employed on the evaluation of dyspnea, yet limited data exist on its assessment of diaphragmatic muscle. This study aimed to determine the capability of CT in identifying ...

    Authors: Pauline Lallement, Alain Boussuges, Paul Habert, Julien Bermudez, Martine Reynaud-Gaubert, Stéphane Delliaux, Fabienne Bregeon and Benjamin Coiffard
    Citation: Respiratory Research 2024 25:135
  30. Neu1 is a sialidase enzyme that plays a crucial role in the regulation of glycosylation in a variety of cellular processes, including cellular signaling and inflammation. In recent years, numerous evidence has...

    Authors: Shiran Mei, Dingding Li, Aoyi Wang, Guoxue Zhu, Bingwen Zhou, Nian Li, Yi Qin, Yanliang Zhang and Shujun Jiang
    Citation: Respiratory Research 2024 25:134
  31. The effects of smoking reduction on the incidence of lung cancer in patients with chronic obstructive pulmonary disease (COPD) are not well known. This study aimed to investigate the effects of changes in smok...

    Authors: Sun Hye Shin, Taeyun Kim, Hyunsoo Kim, Juhee Cho, Danbee Kang and Hye Yun Park
    Citation: Respiratory Research 2024 25:133
  32. Non-tuberculous mycobacteria (NTM) infection is an increasing health problem due to delaying an effective treatment. However, there are few data on 18F-FDG PET/CT for evaluating the status of NTM patients. The ai...

    Authors: Donghe Chen, Yunbo Chen, Shuye Yang, Kanfeng Liu, Zhen Wang, Tingting Zhang, Guolin Wang, Kui Zhao and Xinhui Su
    Citation: Respiratory Research 2024 25:132
  33. The implementation of the Lung Allocation Score (LAS) in the Eurotransplant international collaborative framework decreased waiting list mortality, but organ shortage remains a significant problem. Transplanta...

    Authors: Frank Langer, Philipp M. Lepper, Bettina Weingard, Parviz Aliyev, Robert Bals and Heinrike Wilkens
    Citation: Respiratory Research 2024 25:131
  34. The lung microbiome is an inflammatory stimulus whose role in the development of lung malignancies is incompletely understood. We hypothesized that the lung microbiome associates with multiple clinical factors...

    Authors: Alexa A. Pragman, Shane W. Hodgson, Tianhua Wu, Allison Zank, Rosemary F. Kelly, Cavan S. Reilly and Chris H. Wendt
    Citation: Respiratory Research 2024 25:130
  35. Acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in critically ill patients, and diffuse alveolar damage (DAD) is considered its histological hallmark. Sepsis is one of the m...

    Authors: Natália de Souza Xavier Costa, Giovana da Costa Sigrist, Alexandre Santos Schalch, Luciano Belotti, Marisa Dolhnikoff and Luiz Fernando Ferraz da Silva
    Citation: Respiratory Research 2024 25:129
  36. Adequate cough or exsufflation flow can indicate an option for safe tracheostomy decannulation to noninvasive management. Cough peak flow via the upper airways with the tube capped is an outcome predictor for ...

    Authors: Jingyi Ge, Guangyu Niu, Qing Li, Yi Li, Bo Yang, Haiming Guo, Jianjun Wang, Bin Zhang, Chenxi Zhang, Ting Zhou, Zhanqi Zhao and Hongying Jiang
    Citation: Respiratory Research 2024 25:128
  37. Breathlessness is common in the population and can be related to a range of medical conditions. We aimed to evaluate the burden of breathlessness related to different medical conditions in a middle-aged popula...

    Authors: Magnus Ekström, Josefin Sundh, Anders Andersson, Oskar Angerås, Anders Blomberg, Mats Börjesson, Kenneth Caidahl, Össur Ingi Emilsson, Jan Engvall, Erik Frykholm, Ludger Grote, Kristofer Hedman, Tomas Jernberg, Eva Lindberg, Andrei Malinovschi, André Nyberg…
    Citation: Respiratory Research 2024 25:127
  38. Idiopathic pulmonary fibrosis (IPF) is a progressive disease with a five-year survival rate of less than 40%. There is significant variability in survival time among IPF patients, but the underlying mechanisms...

    Authors: Fei Xu, Yun Tong, Wenjun Yang, Yiyang Cai, Meini Yu, Lei Liu and Qingkang Meng
    Citation: Respiratory Research 2024 25:126
  39. Increasing evidence revealed that lung microbiota dysbiosis was associated with pulmonary infection in lung transplant recipients (LTRs). Pneumocystis jirovecii (P. jirovecii) is an opportunistic fungal pathogen ...

    Authors: Qiaoyan Lian, Xiuling Song, Juhua Yang, Lulin Wang, Peihang Xu, Xiaohua Wang, Xin Xu, Bin Yang, Jianxing He and Chunrong Ju
    Citation: Respiratory Research 2024 25:125
  40. Infliximab is currently recommended as a third-line treatment for refractory sarcoidosis. Data in function of clinical phenotype are currently lacking. We evaluated patients’ characteristics and responses to i...

    Authors: Etienne Rivière, Wendy Jourde, Noémie Gensous, Xavier Demant, Emmanuel Ribeiro, Pierre Duffau, Patrick Mercié, Jean-François Viallard and Estibaliz Lazaro
    Citation: Respiratory Research 2024 25:124
  41. Treatment of Mycobacterium avium complex pulmonary disease (MAC-PD) involves prolonged courses of multiple antibiotics that are variably tolerated and commonly cause adverse drug reactions (ADR). The purpose of t...

    Authors: Meghan Marmor, Husham Sharifi, Susan Jacobs, Kiana Fazeli and Stephen Ruoss
    Citation: Respiratory Research 2024 25:123
  42. Lung function throughout adulthood predicts morbidity and mortality even among adults without chronic respiratory disease. Diet quality may represent a modifiable risk factor for lung function impairment later...

    Authors: Robert C. Wharton, Jing Gennie Wang, Yuni Choi, Elliot Eisenberg, Mariah K. Jackson, Corrine Hanson, Bian Liu, George R. Washko, Ravi Kalhan, David R. Jacobs and Sonali Bose
    Citation: Respiratory Research 2024 25:122
  43. Cardiac dysfunction from pulmonary vascular disease causes characteristic findings on cardiopulmonary exercise testing (CPET). We tested the accuracy of CPET for detecting inadequate stroke volume (SV) augment...

    Authors: Mona Alotaibi, Jenny Z. Yang, Demosthenes G. Papamatheakis, W. Cameron McGuire, Timothy M. Fernandes and Timothy A. Morris
    Citation: Respiratory Research 2024 25:121
  44. Airway basal cells (BC) from patients with chronic obstructive pulmonary disease (COPD) regenerate abnormal airway epithelium and this was associated with reduced expression of several genes involved in epithe...

    Authors: Elizabeth S. McCluskey, Nathan Liu, Abhimaneu Pandey, Nathaniel Marchetti, Steven G. Kelsen and Umadevi S. Sajjan
    Citation: Respiratory Research 2024 25:120
  45. The pattern recognition receptor Dectin-1 was initially discovered to play a pivotal role in mediating pulmonary antifungal immunity and promoting neutrophil-driven inflammation. Recent studies have revealed t...

    Authors: Runjin Cai, Xiaoxiao Gong, Xiaozhao Li, Yuanyuan Jiang, Shuanglinzi Deng, Jiale Tang, Huan Ge, Chendong Wu, Huan Tang, Guo Wang, Lei Xie, Xuemei Chen, Xinyue Hu and Juntao Feng
    Citation: Respiratory Research 2024 25:119
  46. Vitamin D may help to alleviate asthma exacerbation because of its anti-inflammation effect, but the evidence is inconsistent in childhood asthma. MiRNAs are important mediators in asthma pathogenesis and also...

    Authors: Xiaoning Hong, Mingye Jiang, Alvin T. Kho, Anshul Tiwari, Haiyan Guo, Alberta L. Wang, Michael J. McGeachie, Scott T. Weiss, Kelan G. Tantisira and Jiang Li
    Citation: Respiratory Research 2024 25:118
  47. Heart surgery may be complicated by acute lung injury and adult respiratory distress syndrome. Expression and release of mucins MUC5AC and MUC5B in the lungs has been reported to be increased in acute lung inj...

    Authors: Judith van Paassen, Pieter S. Hiemstra, Abraham C. van der Linden, Evert de Jonge, Jaap Jan Zwaginga, Robert J.M. Klautz and M. Sesmu Arbous
    Citation: Respiratory Research 2024 25:117

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