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  1. Peripheral blood oxygen monitoring via chemoreceptors in the carotid body (CB) is an integral function of the autonomic cardiorespiratory regulation. The presence of the purinergic P2Y12 receptor (P2Y12R) has ...

    Authors: András Iring, Mária Baranyi, Bernadett Iring-Varga, Paula Mut-Arbona, Zsuzsanna T. Gál, Dorina Nagy, László Hricisák, János Varga, Zoltán Benyó and Beáta Sperlágh
    Citation: Respiratory Research 2024 25:61
  2. Non-small cell lung cancer (NSCLC) accounts for the vast majority of lung cancers. Early detection is crucial to reduce lung cancer-related mortality. Aberrant DNA methylation occurs early during carcinogenesi...

    Authors: Yunhui Qu, Xiuzhi Zhang, Rong Qiao, Feifei Di, Yakang Song, Jun Wang, Longtao Ji, Jie Zhang, Wanjian Gu, Yifei Fang, Baohui Han, Rongxi Yang, Liping Dai and Songyun Ouyang
    Citation: Respiratory Research 2024 25:59
  3. The circulating metabolome, reflecting underlying cellular processes and disease biology, has not been fully characterized in patients with idiopathic pulmonary fibrosis (IPF). We evaluated whether circulating...

    Authors: Ross Summer, Jamie L. Todd, Megan L. Neely, L. Jason Lobo, Andrew Namen, L. Kristin Newby, Shirin Shafazand, Sally Suliman, Christian Hesslinger, Sascha Keller, Thomas B. Leonard, Scott M. Palmer, Olga Ilkayeva, Michael J. Muehlbauer, Christopher B. Newgard and Jesse Roman
    Citation: Respiratory Research 2024 25:58
  4. Lymphangioleiomyomatosis (LAM) is a rare disease which is easily misdiagnosed. Vascular endothelial growth factor D (VEGF-D), as the most common biomarker, however, is not so perfect for the diagnosis and seve...

    Authors: Xixi Song, Hui Cai, Wenjun Peng, Ke Chen, Zilinuer Abuduxukuer, Yingying Zeng, Guiping Zhu, Chong Lu, Yu Chen, Jian Wang, Ling Ye and Meiling Jin
    Citation: Respiratory Research 2024 25:57
  5. MRproANP and COPAVP are prognostic markers for mortality in chronic obstructive pulmonary disease (COPD). Furthermore, these biomarkers predict mortality due to cardiovascular diseases, which are important pro...

    Authors: S. Fähndrich, C. Herr, S. Teuteberg, P. Alter, S. Söhler, D. Soriano, J. Classen, J. Adams, V. Weinhold, H. Watz, B. Waschki, T. Zeller, M. Eichenlaub, F. C. Trudzinski, J. D. Michels, A. Omlor…
    Citation: Respiratory Research 2024 25:56
  6. Alveolar hypercoagulation and fibrinolytic inhibition are mainly responsible for massive alveolar fibrin deposition, which are closely related with refractory hypoxemia in acute respiratory distress syndrome (...

    Authors: Chuan Xiao, Jiaoyangzi Liu, Yumei Cheng, Yingxia Wu, Qing Li, Xianjun Chen, Jia Yuan, Qi Dong, Lu Li, Ying liu and Feng Shen
    Citation: Respiratory Research 2024 25:54
  7. Computed tomography (CT) scan is commonly performed for pleural effusion diagnostis in the clinic. However, there are limited data assessing the accuracy of thoracic CT for the separation of transudative from ...

    Authors: Yan Zhang, Yang Zhang, Wei Wang, Xiaoyu Feng, Jiahuan Guo, Bo Chen, Fuyun Zhang, Huanhuan Wang, Mengnan Fan, Yingwei Zhu, Yuxia Sun, Tongsheng Wang, Yimin Mao and Pengfei Gao
    Citation: Respiratory Research 2024 25:53
  8. Mucus plugs have been described in the airways of asthmatic subjects, particularly those with associated with type 2 inflammation and sputum eosinophilia. In the current study we addressed the question of whet...

    Authors: Camille Audousset, Sana Swaleh, Ron Olivenstein, Motahareh Vameghestahbanati, Miranda Kirby, Alexandre Semionov, Benjamin M. Smith and James G. Martin
    Citation: Respiratory Research 2024 25:52
  9. Several researches have demonstrated that patients with sarcoidosis accompanied with the abnormality in blood glucose and/or lipids, however, the causal relationship between them remains uncertain. To elucidat...

    Authors: Yuan Zhan, Jiaheng Zhang, Ruonan Yang, Zhesong Deng, Shanshan Chen, Jie Feng, Jixing Wu, Qian Huang, Yiya Gu and Jungang Xie
    Citation: Respiratory Research 2024 25:50
  10. Chronic obstructive pulmonary disease (COPD) has the highest increased risk due to household air pollution arising from biomass fuel burning. However, knowledge on COPD patho-mechanisms is mainly limited to to...

    Authors: Swapna Upadhyay, Mizanur Rahman, Selina Rinaldi, Jeremy Koelmel, Elizabeth Z. Lin, Padukudru Anand Mahesh, Johannes Beckers, Gunnar Johanson, Krystal J. Godri Pollitt, Lena Palmberg, Martin Irmler and Koustav Ganguly
    Citation: Respiratory Research 2024 25:49
  11. Neutrophil extracellular traps (NETs) have repeatedly been related to COVID-19 severity and mortality. However, there is no consensus on their quantification, and there are scarce data on their evolution durin...

    Authors: Cristina de Diego, Ana Belén Lasierra, Lucía López-Vergara, Laura Torralba, Pablo Ruiz de Gopegui, Raquel Lahoz, Claudia Abadía, Javier Godino, Alberto Cebollada, Beatriz Jimeno, Carlota Bello, Antonio Tejada and Salvador Bello
    Citation: Respiratory Research 2024 25:48
  12. Malignant pleural effusion (MPE) is a common complication of thoracic and extrathoracic malignancies and is associated with high mortality and elevated costs to healthcare systems. Over the last decades the un...

    Authors: Francesca Gonnelli, Wafa Hassan, Martina Bonifazi, Valentina Pinelli, Eihab O Bedawi, José M. Porcel, Najib M Rahman and Federico Mei
    Citation: Respiratory Research 2024 25:47
  13. Numerous studies have documented significant alterations in the bodily fluids of Chronic Obstructive Pulmonary Disease (COPD) patients. However, existing literature lacks causal inference due to residual confo...

    Authors: Zhangkai J. Cheng, Haojie Wu, Zhenglin Chang, Jiahao Cheng, Suilin Wang, Changlian Liu, Yanxi Zhang, Shiliang Xu, Qiongqiong Wan, JinWen Ron, Kemin Liu and Baoqing Sun
    Citation: Respiratory Research 2024 25:46
  14. Severe community-acquired pneumonia (S-CAP) is a public health threat, making it essential to identify novel biomarkers and investigate the underlying mechanisms of disease severity.

    Authors: Jieqiong Li, Yawen Wang, Weichao Zhao, Tingyu Yang, Qianyu Zhang, Huqin Yang, Xuyan Li and Zhaohui Tong
    Citation: Respiratory Research 2024 25:45
  15. A decline in forced expiratory volume (FEV1) is a hallmark of respiratory diseases that are an important cause of morbidity among the elderly. While some data exist on biomarkers that are related to FEV1, we s...

    Authors: Gisli Thor Axelsson, Thorarinn Jonmundsson, Youngjae Woo, Elisabet Alexandra Frick, Thor Aspelund, Joseph J. Loureiro, Anthony P. Orth, Lori L. Jennings, Gunnar Gudmundsson, Valur Emilsson, Valborg Gudmundsdottir and Vilmundur Gudnason
    Citation: Respiratory Research 2024 25:44
  16. Randomised control trials (RCTs) with strict eligibility criteria can lead to trial populations not commonly seen in clinical practice. We described the proportion of people with chronic obstructive pulmonary ...

    Authors: Hannah R. Whittaker, Aria Torkpour and Jennifer Quint
    Citation: Respiratory Research 2024 25:43
  17. Good biological indicators capable of predicting chronic obstructive pulmonary disease (COPD) phenotypes and clinical trajectories are lacking. Because nuclear and mitochondrial genomes are damaged and release...

    Authors: Sarah A. Ware, Corrine R. Kliment, Luca Giordano, Kevin M. Redding, William L. Rumsey, Stewart Bates, Yingze Zhang, Frank C. Sciurba, S. Mehdi Nouraie and Brett A. Kaufman
    Citation: Respiratory Research 2024 25:42
  18. Patients with fibrotic hypersensitivity pneumonitis (f-HP) have varied clinical and radiologic presentations whose associated phenotypic outcomes have not been previously described. We conducted a study to eva...

    Authors: Tananchai Petnak, Wisit Cheungpasitporn, Charat Thongprayoon, Tulaton Sodsri, Supawit Tangpanithandee and Teng Moua
    Citation: Respiratory Research 2024 25:41
  19. Although EGFR-TKI resistance mechanisms in non-small cell lung cancer (NSCLC) have been extensively studied, certain patient subgroups remain with unclear mechanisms. This retrospective study analysed mutation...

    Authors: Wuwu Ding, Pengmin Yang, Xiaokai Zhao, Xiaozhi Wang, Huaqing Liu, Qing Su, Xintao Wang, Jieyi Li, Ziying Gong, Daoyun Zhang and Xinwei Wang
    Citation: Respiratory Research 2024 25:40
  20. The COVID-19 pandemic has constrained access to spirometry, and the inherent risk of infectious transmission during aerosol-generating procedures has necessitated the rapid development of Remotely Supervised S...

    Authors: Łukasz Kołtowski, Mikołaj Basza, Wojciech Bojanowicz, Piotr Dąbrowiecki, Mateusz Soliński, Katarzyna Górska, Piotr Korczyński and Lauren E. Eggert
    Citation: Respiratory Research 2024 25:39
  21. Chronic obstructive pulmonary disease (COPD) is an inflammatory multisystemic disease caused by environmental exposures and/or genetic factors. Inherited alpha-1-antitrypsin deficiency (AATD) is one of the best ...

    Authors: Daniela Zöller, Christian Haverkamp, Adeline Makoudjou, Ghislain Sofack, Saskia Kiefer, Denis Gebele, Michelle Pfaffenlehner, Martin Boeker, Harald Binder, Kapil Karki, Christian Seidemann, Bernd Schmeck, Timm Greulich, Harald Renz, Stefanie Schild, Susanne A. Seuchter…
    Citation: Respiratory Research 2024 25:38
  22. Acute respiratory distress syndrome (ARDS) alters the dynamics of lung inflation during mechanical ventilation. Repetitive alveolar collapse and expansion (RACE) predisposes the lung to ventilator-induced lung...

    Authors: Hassan Al-Khalisy, Gary F. Nieman, Michaela Kollisch-Singule, Penny Andrews, Luigi Camporota, Joseph Shiber, Toni Manougian, Joshua Satalin, Sarah Blair, Auyon Ghosh, Jacob Herrmann, David W. Kaczka, Donald P. Gaver, Jason H. T. Bates and Nader M. Habashi
    Citation: Respiratory Research 2024 25:37
  23. Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is a common and preventable event in patients with chronic obstructive pulmonary disease (COPD). Data regarding the impact of AECOPD on shor...

    Authors: Wang Chun Kwok, Terence C. C. Tam, James C. M. Ho, David C. L. Lam, Mary S. M. Ip and Desmond Y. H. Yap
    Citation: Respiratory Research 2024 25:36
  24. This study aimed to investigate the interactions among three core elements of respiratory infection—pathogen, lung microbiome, and host response—and their avocation with the severity and outcomes of Mycoplasma pn...

    Authors: Xia Huang, Yingying Luo, Jing Wang, Xuefang Zhang, Lei Chen, Ruxi Wu, Zhengyang Xue, Haiyan Gu, Daiying Li, Heng Tang, Houbing Qin, Deyu Zhao and Feng Liu
    Citation: Respiratory Research 2024 25:35
  25. COVID-19-induced acute respiratory distress syndrome (ARDS) can result in tissue damage and multiple organ dysfunction, especially in kidney transplant recipients (KTRs) receiving immunosuppressive drugs. Pres...

    Authors: Junyu Lu, Yin Chen, Kaihuan Zhou, Yicong Ling, Qianqian Qin, Weisheng Lu, Lian Qin, Chenglin Mou, Jianfeng Zhang, Xiaowen Zheng and Ke Qin
    Citation: Respiratory Research 2024 25:34
  26. No single pulmonary function test captures the functional effect of emphysema in idiopathic pulmonary fibrosis (IPF). Without experienced radiologists, other methods are needed to determine emphysema extent. H...

    Authors: Athol U. Wells, Joseph Jacob, Nicola Sverzellati, Gary Cross, Joseph Barnett, Angelo De Lauretis, Katerina Antoniou, Derek Weycker, Mark Atwood, Klaus-Uwe Kirchgaessler and Vincent Cottin
    Citation: Respiratory Research 2024 25:33
  27. Breath testing using an electronic nose has been recognized as a promising new technique for the early detection of lung cancer. Imbalanced data are commonly observed in electronic nose studies, but methods to...

    Authors: Ke-Cheng Chen, Shuenn-Wen Kuo, Ruei-Hao Shie and Hsiao-Yu Yang
    Citation: Respiratory Research 2024 25:32
  28. Drug-induced interstitial lung disease (DILD) is a lung injury caused by various types of drugs and is a serious problem in both clinical practice and drug development. Clinical management of the condition wou...

    Authors: Yuchen Sun, Kosuke Saito, Atsuhito Ushiki, Mitsuhiro Abe, Yoshinobu Saito, Takeru Kashiwada, Yasushi Horimasu, Akihiko Gemma, Koichiro Tatsumi, Noboru Hattori, Kenji Tsushima, Kazuhisa Takemoto, Rika Ishikawa, Toshiko Momiyama, Shin-ichiro Matsuyama, Noriaki Arakawa…
    Citation: Respiratory Research 2024 25:31
  29. Tissue-engineered tracheal grafts (TETG) can be recellularized by the host or pre-seeded with host-derived cells. However, the impact of airway disease on the recellularization process is unknown.

    Authors: Lisa Zhang, Natalie Kelly, Kimberly M Shontz, Cynthia L. Hill, Jacob T. Stack, Jazmin Calyeca, Laura Matrka, Audrey Miller, Susan D Reynolds and Tendy Chiang
    Citation: Respiratory Research 2024 25:28
  30. Venovenous extracorporeal membrane oxygenation (VV ECMO) has been widely used for severe acute respiratory distress syndrome (ARDS) in recent years. However, the role of hemoadsorption in ARDS patients requiri...

    Authors: Wenli Li, Yuansen Chen, Duo Li, Xiangyan Meng, Ziquan Liu, Yanqing Liu and Haojun Fan
    Citation: Respiratory Research 2024 25:27
  31. Honeycomb cysts (HC) within the alveolar region are distinct histopathological features in the lungs of idiopathic pulmonary fibrosis (IPF) patients. HC are lined with a single-or stratified layer of basal cel...

    Authors: Sabrina Blumer, Petra Khan, Nataliia Artysh, Linda Plappert, Spasenija Savic, Lars Knudsen, Danny Jonigk, Mark P. Kuehnel, Antje  Prasse and Katrin E. Hostettler
    Citation: Respiratory Research 2024 25:26
  32. Drug-induced interstitial lung disease (DIILD) is a serious adverse event potentially induced by any antineoplastic agent. Whether cancer patients are predisposed to a higher risk of DIILD after receiving immu...

    Authors: Yoshihiro Kitahara, Yusuke Inoue, Hideki Yasui, Masato Karayama, Yuzo Suzuki, Hironao Hozumi, Kazuki Furuhashi, Noriyuki Enomoto, Tomoyuki Fujisawa, Kazuhito Funai, Tetsuya Honda, Kiyoshi Misawa, Hideaki Miyake, Hiroya Takeuchi, Naoki Inui and Takafumi Suda
    Citation: Respiratory Research 2024 25:25
  33. The substantial heterogeneity of clinical presentations in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia still requires robust chest computed tomography analysis to ident...

    Authors: Yusuke Kataoka, Naoya Tanabe, Masahiro Shirata, Nobuyoshi Hamao, Issei Oi, Tomoki Maetani, Yusuke Shiraishi, Kentaro Hashimoto, Masatoshi Yamazoe, Hiroshi Shima, Hitomi Ajimizu, Tsuyoshi Oguma, Masahito Emura, Kazuo Endo, Yoshinori Hasegawa, Tadashi Mio…
    Citation: Respiratory Research 2024 25:24
  34. Electronic cigarette (e-cig) vaping has increased in the past decade in the US, and e-cig use is misleadingly marketed as a safe cessation for quitting smoking. The main constituents in e-liquid are humectants...

    Authors: Qixin Wang, Joseph H Lucas, Cortney Pang, Ruogang Zhao and Irfan Rahman
    Citation: Respiratory Research 2024 25:23
  35. Malignant pleural effusion is mostly a complication of advanced malignant tumors. However, the cancer markers such as carbohydrate antigen 125 (CA 125), carbohydrate antigen 15-3 (CA 15-3), carbohydrate antige...

    Authors: Xiaoqiong Wang, Xingya Yan, Zhipeng Zhang, Chuchu Xu, Fangbin Du, Yanghu Xie, Xiaona Yin, Zubao Lei, Yinling Jiang, Wanchun Yang, Xuan Zhou and Yongsheng Wang
    Citation: Respiratory Research 2024 25:22
  36. Dyspnea conveys an upsetting or distressing experience of breathing awareness. It heavily weighs on chronic respiratory disease patients, particularly when it persists despite maximal treatment of causative ab...

    Authors: Jonathan Dedonder, Christelle Gelgon, Antoine Guerder, Nathalie Nion, Sophie Lavault, Capucine Morélot-Panzini, Jésus Gonzalez-Bermejo, Laelia Benoit, Thomas Similowski and Laure Serresse
    Citation: Respiratory Research 2024 25:21
  37. Adenosine deaminase (ADA) is a useful biomarker for the diagnosis of tuberculous pleurisy (TBP). However, pleural effusions with high ADA can also be caused by other diseases, particularly hematologic malignan...

    Authors: Junsu Choe, Sun Hye Shin, Kyeongman Jeon, Hee Jae Huh, Hyung-Doo Park and Byeong-Ho Jeong
    Citation: Respiratory Research 2024 25:17
  38. Growing evidence from observational studies and clinical trials suggests that the gut microbiota is associated with tuberculosis (TB). However, it is unclear whether any causal relationship exists between them...

    Authors: Zongxiang Yuan, Yiwen Kang, Chuye Mo, Shihui Huang, Fang Qin, Junhan Zhang, Fengyi Wang, Junjun Jiang, Xiaoxiang Yang, Hao Liang and Li Ye
    Citation: Respiratory Research 2024 25:16
  39. While regular cigar smoking is believed to carry similar health risks as regular cigarette smoking, the impact of cigar use, alone or in combination with cigarettes, on obstructive pulmonary disease (COPD) has...

    Authors: Steven Cook, James H. Buszkiewicz, David T. Levy, Rafael Meza and Nancy L. Fleischer
    Citation: Respiratory Research 2024 25:13

    The Correction to this article has been published in Respiratory Research 2024 25:98

  40. There are relatively few data about the ultrasound evaluation of pleural line in patients with respiratory failure. We measured the pleural line thickness during different phases of the respiratory cycle in ne...

    Authors: Barbara Loi, Pasquale Fabio Barra, Laura Vivalda, Francesco Raimondi and Daniele De Luca
    Citation: Respiratory Research 2024 25:12
  41. Although Traditional Chinese Medicine (TCM) has been used for treating asthma for centuries, the understanding of its mechanism of action is still limited. Thus, the purpose of this study was to explore the po...

    Authors: Wang Peng, Qinxuan Xia, Yue Zhang, Danfeng Cao and Xiangrong Zheng
    Citation: Respiratory Research 2024 25:10
  42. Patients with influenza-related acute respiratory distress syndrome (ARDS) are critically ill and require mechanical ventilation (MV) support. Prolonged mechanical ventilation (PMV) is often seen in these case...

    Authors: Pai-Chi Hsu, Yi-Tsung Lin, Kuo-Chin Kao, Chung-Kan Peng, Chau-Chyun Sheu, Shinn-Jye Liang, Ming-Cheng Chan, Hao-Chien Wang, Yu-Mu Chen, Wei-Chih Chen and Kuang-Yao Yang
    Citation: Respiratory Research 2024 25:9
  43. The mortality rate of acute respiratory distress syndrome (ARDS) increases with age (≥ 65 years old) in critically ill patients, and it is necessary to prevent mortality in elderly patients with ARDS in the in...

    Authors: Mingzhuo Li, Fen Liu, Yang Yang, Jiahui Lao, Chaonan Yin, Yafei Wu, Zhongshang Yuan, Yongyue Wei and Fang Tang
    Citation: Respiratory Research 2024 25:8
  44. Excessive pulmonary inflammation is the hallmark of respiratory syncytial virus (RSV) infection hindering efficacious RSV vaccine development. Yet, the vast majority of the experimental RSV vaccine studies use...

    Authors: Min-Ju Kim, Ki Back Chu, Su-Hwa Lee, Jie Mao, Gi-Deok Eom, Keon-Woong Yoon, Eun-Kyung Moon and Fu-Shi Quan
    Citation: Respiratory Research 2024 25:7
  45. Airway remodeling is a poorly reversible feature of asthma which lacks effective therapeutic interventions. CD147 can regulate extracellular matrix (ECM) remodeling and tissue fibrosis, and participate in the ...

    Authors: Zhao Li, Tao Cheng, Yaning Guo, Rong Gao, Xuankun Ma, Xuecong Mao and Xinpeng Han
    Citation: Respiratory Research 2024 25:6
  46. Lung recruitment and continuous distending pressure (CDP) titration are critical for assuring the efficacy of high-frequency ventilation (HFOV) in preterm infants. The limitation of oxygenation (peripheral oxy...

    Authors: Chiara Veneroni, Raffaele L. Dellacà, Erik Küng, Beatrice Bonomi, Angelika Berger and Tobias Werther
    Citation: Respiratory Research 2024 25:4

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