Vestbo J, Hurd SS, Agusti AG, Jones PW, Vogelmeier C, Anzueto A, Barnes PJ, Fabbri LM, Martinez FJ, Nishimura M, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2013;187:347–65.
Article
CAS
Google Scholar
Barnes PJ. Chronic obstructive pulmonary disease: a growing but neglected global epidemic. PLoS Med. 2007;4:e112.
Article
Google Scholar
Lamprecht B, McBurnie MA, Vollmer WM, Gudmundsson G, Welte T, Nizankowska-Mogilnicka E, Studnicka M, Bateman E, Anto JM, Burney P, et al. COPD in never smokers: results from the population-based burden of obstructive lung disease study. Chest. 2011;139:752–63.
Article
Google Scholar
COPD. Improving prevention and care. Lancet. 2015;385:830.
Google Scholar
Salvi SS, Barnes PJ. Chronic obstructive pulmonary disease in non-smokers. Lancet. 2009;374:733–43.
Article
Google Scholar
Song C, He J, Wu L, Jin T, Chen X, Li R, Ren P, Zhang L, Mao H. Health burden attributable to ambient PM2.5 in China. Environ Pollut. 2017;223:575–86.
Article
CAS
Google Scholar
Pope CA 3rd, Burnett RT, Turner MC, Cohen A, Krewski D, Jerrett M, Gapstur SM, Thun MJ. Lung cancer and cardiovascular disease mortality associated with ambient air pollution and cigarette smoke: shape of the exposure-response relationships. Environ Health Perspect. 2011;119:1616–21.
Article
Google Scholar
Lin H, Guo Y, Di Q, Zheng Y, Kowal P, Xiao J, Liu T, Li X, Zeng W, Howard SW, et al. Ambient PM2.5 and stroke: effect modifiers and population attributable risk in six low- and middle-income countries. Stroke. 2017;48:1191–7.
Article
CAS
Google Scholar
Lin H, Guo Y, Zheng Y, Di Q, Liu T, Xiao J, Li X, Zeng W, Cummings-Vaughn LA, Howard SW, et al. Long-term effects of ambient PM2.5 on hypertension and blood pressure and attributable risk among older Chinese adults. Hypertension. 2017;69:806–12.
Article
CAS
Google Scholar
Gan WQ, FitzGerald JM, Carlsten C, Sadatsafavi M, Brauer M. Associations of ambient air pollution with chronic obstructive pulmonary disease hospitalization and mortality. Am J Respir Crit Care Med. 2013;187:721–7.
Article
Google Scholar
Lepeule J, Laden F, Dockery D, Schwartz J. Chronic exposure to fine particles and mortality: an extended follow-up of the Harvard six cities study from 1974 to 2009. Environ Health Perspect. 2012;120:965–70.
Article
Google Scholar
Dominici F, Peng RD, Bell ML, Pham L, McDermott A, Zeger SL, Samet JM. Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseases. JAMA. 2006;295:1127–34.
Article
CAS
Google Scholar
Sint T, Donohue JF, Ghio AJ. Ambient air pollution particles and the acute exacerbation of chronic obstructive pulmonary disease. Inhal Toxicol. 2008;20:25–9.
Article
CAS
Google Scholar
Weichenthal SA, Lavigne E, Evans GJ, Godri Pollitt KJ, Burnett RT. Fine particulate matter and emergency room visits for respiratory illness. Effect modification by oxidative potential. Am J Respir Crit Care Med. 2016;194:577–86.
Article
CAS
Google Scholar
Lagorio S, Forastiere F, Pistelli R, Iavarone I, Michelozzi P, Fano V, Marconi A, Ziemacki G, Ostro BD. Air pollution and lung function among susceptible adult subjects: a panel study. Environ Health. 2006;5:11.
Article
Google Scholar
Kopp J, Flessa S, Lieb W, Markus MRP, Teumer A, Homuth G, Wallaschofski H, Marschall P, Volzke H, Baumeister SE. Association of PNPLA3 rs738409 and TM6SF2 rs58542926 with health services utilization in a population-based study. BMC Health Serv Res. 2016;16:41.
Article
Google Scholar
Apte JS, Marshall JD, Cohen AJ, Brauer M. Addressing global mortality from ambient PM2.5. Environ Sci Technol. 2015;49:8057–66.
Article
CAS
Google Scholar
Schikowski T, Ranft U, Sugiri D, Vierkotter A, Bruning T, Harth V, Kramer U. Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women. Respir Res. 2010;11:113.
Article
Google Scholar
Xie J, Zhao J, Xiao C, Xu Y, Yang S, Ni W. Reduced heat shock protein 70 in airway smooth muscle in patients with chronic obstructive pulmonary disease. Exp Lung Res. 2010;36:219–26.
Article
CAS
Google Scholar
Xie J, Wu H, Xu Y, Wu X, Liu X, Shang J, Zhao J, Zhao J, Wang J, Dela Cruz CS, et al. Gene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline. Respir Res. 2015;16:49.
Article
Google Scholar
Wu H, Yang S, Wu X, Zhao J, Zhao J, Ning Q, Xu Y, Xie J. Interleukin-33/ST2 signaling promotes production of interleukin-6 and interleukin-8 in systemic inflammation in cigarette smoke-induced chronic obstructive pulmonary disease mice. Biochem Biophys Res Commun. 2014;450:110–6.
Article
CAS
Google Scholar
Sun Q, Yue P, Deiuliis JA, Lumeng CN, Kampfrath T, Mikolaj MB, Cai Y, Ostrowski MC, Lu B, Parthasarathy S, et al. Ambient air pollution exaggerates adipose inflammation and insulin resistance in a mouse model of diet-induced obesity. Circulation. 2009;119:538–46.
Article
CAS
Google Scholar
Zeng Z, Li M, Chen J, Li Q, Ning Q, Zhao J, Xu Y, Xie J, Yu J. Reduced MBD2 expression enhances airway inflammation in bronchial epithelium in COPD. Int J Chron Obstruct Pulmon Dis. 2018;13:703–15.
Article
Google Scholar
D'Hulst AI, Vermaelen KY, Brusselle GG, Joos GF, Pauwels RA. Time course of cigarette smoke-induced pulmonary inflammation in mice. Eur Respir J. 2005;26:204–13.
Article
CAS
Google Scholar
Bracke KR, D'Hulst AI, Maes T, Moerloose KB, Demedts IK, Lebecque S, Joos GF, Brusselle GG. Cigarette smoke-induced pulmonary inflammation and emphysema are attenuated in CCR6-deficient mice. J Immunol. 2006;177:4350–9.
Article
CAS
Google Scholar
Barnes PJ, Shapiro SD, Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J. 2003;22:672–88.
Article
CAS
Google Scholar
Barnes PJ. The cytokine network in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2009;41:631–8.
Article
CAS
Google Scholar
D'Hulst AI, Maes T, Bracke KR, Demedts IK, Tournoy KG, Joos GF, Brusselle GG. Cigarette smoke-induced pulmonary emphysema in scid-mice. Is the acquired immune system required? Respir Res. 2005;6:147.
Article
Google Scholar
van der Strate BW, Postma DS, Brandsma CA, Melgert BN, Luinge MA, Geerlings M, Hylkema MN, van den Berg A, Timens W, Kerstjens HA. Cigarette smoke-induced emphysema: a role for the B cell? Am J Respir Crit Care Med. 2006;173:751–8.
Article
Google Scholar
Pope CA 3rd, Burnett RT, Thun MJ, Calle EE, Krewski D, Ito K, Thurston GD. Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. JAMA. 2002;287:1132–41.
Article
CAS
Google Scholar
Samet JM, Dominici F, Curriero FC, Coursac I, Zeger SL. Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994. N Engl J Med. 2000;343:1742–9.
Article
CAS
Google Scholar
Guan WJ, Zheng XY, Chung KF, Zhong NS. Impact of air pollution on the burden of chronic respiratory diseases in China: time for urgent action. Lancet. 2016;388:1939–51.
Article
Google Scholar
Li MH, Fan LC, Mao B, Yang JW, Choi AM, Cao WJ, Xu JF. Short-term exposure to ambient fine particulate matter increases hospitalizations and mortality in COPD: a systematic review and meta-analysis. Chest. 2016;149:447–58.
Article
Google Scholar
Duvall RM, Norris GA, Dailey LA, Burke JM, McGee JK, Gilmour MI, Gordon T, Devlin RB. Source apportionment of particulate matter in the U.S. and associations with lung inflammatory markers. Inhal Toxicol. 2008;20:671–83.
Article
CAS
Google Scholar
Hetland RB, Cassee FR, Refsnes M, Schwarze PE, Lag M, Boere AJ, Dybing E. Release of inflammatory cytokines, cell toxicity and apoptosis in epithelial lung cells after exposure to ambient air particles of different size fractions. Toxicol in Vitro. 2004;18:203–12.
Article
CAS
Google Scholar
Wilfong ER, Lyles M, Rietcheck RL, Arfsten DP, Boeckman HJ, Johnson EW, Doyle TL, Chapman GD. The acute and long-term effects of Middle East sand particles on the rat airway following a single intratracheal instillation. J Toxicol Environ Health A. 2011;74:1351–65.
Article
CAS
Google Scholar
Elad D, Zaretsky U, Avraham S, Gotlieb R, Wolf M, Katra I, Sarig S, Zaady E. In vitro exposure of nasal epithelial cells to atmospheric dust. Biomech Model Mechanobiol. 2018.
Atkinson JJ, Senior RM. Matrix metalloproteinase-9 in lung remodeling. Am J Respir Cell Mol Biol. 2003;28:12–24.
Article
CAS
Google Scholar
Border WA, Noble NA. Transforming growth factor beta in tissue fibrosis. N Engl J Med. 1994;331:1286–92.
Article
CAS
Google Scholar
Bonniaud P, Kolb M, Galt T, Robertson J, Robbins C, Stampfli M, Lavery C, Margetts PJ, Roberts AB, Gauldie J. Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis. J Immunol. 2004;173:2099–108.
Article
CAS
Google Scholar
Feinberg MW, Jain MK, Werner F, Sibinga NE, Wiesel P, Wang H, Topper JN, Perrella MA, Lee ME. Transforming growth factor-beta 1 inhibits cytokine-mediated induction of human metalloelastase in macrophages. J Biol Chem. 2000;275:25766–73.
Article
CAS
Google Scholar