Skip to main content

Articles

Page 5 of 61

  1. Cognitive and motor-performance decline with age and the process is accelerated by decline in general health. In this study, we aimed to estimate the effects of COPD and HB levels on cognitive and motor perfor...

    Authors: Inken Padberg, Alice Schneider, Jessica Lee Rohmann, Sean Walter Kelley, Ulrike Grittner and Bob Siegerink

    Citation: Respiratory Research 2020 21:40

    Content type: Research

    Published on:

  2. Recent studies have shown 6'-O-galloylpaeoniflorin (GPF), a nature product extracted from the roots of paeoniflorin exerts anti-oxidant and anti-inflammatory activities. However, the effects of GPF on the prol...

    Authors: Jinying Gao, Lei Song, Huan Xia, Liping Peng and Zhongmei Wen

    Citation: Respiratory Research 2020 21:39

    Content type: Research

    Published on:

  3. Idiopathic pulmonary fibrosis (IPF) is a devastating disease with a median survival of only three to 5 years. Fibroblast proliferation is a hallmark of IPF as is secretion of extracellular matrix proteins from...

    Authors: Tomohito Yoshihara, Yasuhiro Nanri, Satoshi Nunomura, Yukie Yamaguchi, Carol Feghali-Bostwick, Keiichi Ajito, Shoichi Murakami, Masaaki Mawatari and Kenji Izuhara

    Citation: Respiratory Research 2020 21:38

    Content type: Research

    Published on:

  4. A persistent low inflammatory-oxidative status and the inadequacy of the antioxidant nuclear factor-E2-related factor 2 (Nrf2) have been implicated in chronic obstructive pulmonary disease (COPD) progression. ...

    Authors: A. M. Fratta Pasini, C. Stranieri, M. Ferrari, U. Garbin, L. Cazzoletti, C. Mozzini, F. Spelta, D. Peserico and L. Cominacini

    Citation: Respiratory Research 2020 21:37

    Content type: Research

    Published on:

    The Correction to this article has been published in Respiratory Research 2020 21:213

  5. In the Phase III INPULSIS® trials, treatment of patients with idiopathic pulmonary fibrosis (IPF) with nintedanib significantly reduced the annual rate of decline in forced vital capacity (FVC) versus placebo,...

    Authors: Michael Kreuter, Wim A. Wuyts, Marlies Wijsenbeek, Sabrina Bajwah, Toby M. Maher, Susanne Stowasser, Natalia Male, Wibke Stansen, Nils Schoof, Leticia Orsatti and Jeffrey Swigris

    Citation: Respiratory Research 2020 21:36

    Content type: Research

    Published on:

  6. Obstructive sleep apnea syndrome (OSA) is currently recognized as an independent risk factor for hypertension, arrhythmia, coronary heart disease, stroke, and metabolic disorders (e.g. diabetes, dyslipidemia)....

    Authors: Stephanie André, Fabio Andreozzi, Chloé Van Overstraeten, Sidali Ben Youssef, Ionela Bold, Sarah Carlier, Alexia Gruwez, Anne-Violette Bruyneel and Marie Bruyneel

    Citation: Respiratory Research 2020 21:35

    Content type: Research

    Published on:

  7. After publication of our article [1] the authors have notified us that one of the names has been incorrectly tagged.

    Authors: David Bennett, Paolo Cameli, Nicola Lanzarone, Loredana Carobene, Nicola Bianchi, Annalisa Fui, Luigi Rizzi, Laura Bergantini, Giuseppe Cillis, Miriana d’Alessandro, Maria Antonietta Mazzei, Rosa Metella Refini, Piersante Sestini, Elena Bargagli and Paola Rottoli

    Citation: Respiratory Research 2020 21:34

    Content type: Correction

    Published on:

    The original article was published in Respiratory Research 2020 21:6

  8. Interleukin 15 (IL-15) is a growth and modulating factor for B, T lymphocytes and natural killer cells (NK). Its action on innate and adaptive immunity is modulated by its alpha chain receptor (IL-15Rα). The I...

    Authors: Antoine Moui, Martin Klein, Dorian Hassoun, Eléonore Dijoux, Marie-Aude Cheminant, Antoine Magnan and Grégory Bouchaud

    Citation: Respiratory Research 2020 21:33

    Content type: Research

    Published on:

  9. Fibrotic interstitial lung diseases (ILDs) are often challenging to diagnose and classify, but an accurate diagnosis has significant implications for both treatment and prognosis. A subset of patients with fib...

    Authors: Alyson W. Wong, Christopher J. Ryerson and Sabina A. Guler

    Citation: Respiratory Research 2020 21:32

    Content type: Review

    Published on:

  10. Global gene expression levels are known to be highly dependent upon gross demographic features including age, yet identification of age-related genomic indicators has yet to be comprehensively undertaken in a ...

    Authors: Michael J. McGeachie, Joanne E. Sordillo, Amber Dahlin, Alberta L. Wang, Sharon M. Lutz, Kelan G. Tantisira, Ronald Panganiban, Quan Lu, Satria Sajuthi, Cydney Urbanek, Rachel Kelly, Benjamin Saef, Celeste Eng, Sam S. Oh, Alvin T. Kho, Damien C. Croteau-Chonka…

    Citation: Respiratory Research 2020 21:31

    Content type: Research

    Published on:

  11. Alveolar macrophages are professional phagocytes that remove microbial pathogens inhaled into the lung. The phagocytic ability is compromised in chronic obstructive pulmonary disease (COPD). However, the molec...

    Authors: Atsushi Tanno, Naoya Fujino, Mitsuhiro Yamada, Hisatoshi Sugiura, Taizou Hirano, Rie Tanaka, Hirohito Sano, Satoshi Suzuki, Yoshinori Okada and Masakazu Ichinose

    Citation: Respiratory Research 2020 21:30

    Content type: Research

    Published on:

  12. After publication of our article [1], we have been notified that an extra alpha symbol (α) was mistakenly added at the beginning of the title.

    Authors: Kristina Krempaska, Sandra Barnowski, Jacopo Gavini, Nina Hobi, Simone Ebener, Cedric Simillion, Andrea Stokes, Ronja Schliep, Lars Knudsen, Thomas K. Geiser and Manuela Funke-Chambour

    Citation: Respiratory Research 2020 21:29

    Content type: Correction

    Published on:

    The original article was published in Respiratory Research 2020 21:25

  13. Peripheral neuropathy is a common comorbidity in COPD. We aimed to investigate associations between alterations commonly found in COPD and peripheral neuropathy, with particular emphasize on the distinction be...

    Authors: K. Kahnert, M. Föhrenbach, T. Lucke, P. Alter, F. T. Trudzinski, R. Bals, J. I. Lutter, H. Timmermann, S. Söhler, S. Förderreuther, D. Nowak, H. Watz, B. Waschki, J. Behr, T. Welte, C. F. Vogelmeier…

    Citation: Respiratory Research 2020 21:28

    Content type: Research

    Published on:

  14. Reduced physical capacity (PC) and physical activity (PA) are common in COPD patients and associated with poor outcome. However, they represent different aspects of physical functioning and interventions do no...

    Authors: Noriane A. Sievi, Thomas Brack, Martin H. Brutsche, Martin Frey, Sarosh Irani, Jörg D. Leuppi, Robert Thurnheer, Malcolm Kohler and Christian F. Clarenbach

    Citation: Respiratory Research 2020 21:27

    Content type: Research

    Published on:

    The Letter to the Editor to this article has been published in Respiratory Research 2020 21:112

  15. Studies suggest that acute decreases in lung hyperinflation at rest improves cardiac function and increases lung vascular perfusion from decompression of a compromised heart. In those studies, changes in resti...

    Authors: Miguel J. Divo, Michael R. DePietro, John R. Horton, Cherie A. Maguire and Bartolome R. Celli

    Citation: Respiratory Research 2020 21:26

    Content type: Research

    Published on:

  16. Idiopathic pulmonary fibrosis (IPF) is a chronic fatal lung disease without a cure and new drug strategies are urgently needed. Differences in behavior between diseased and healthy cells are well known and dru...

    Authors: Kristina Krempaska, Sandra Barnowski, Jacopo Gavini, Nina Hobi, Simone Ebener, Cedric Simillion, Andrea Stokes, Ronja Schliep, Lars Knudsen, Thomas K. Geiser and Manuela Funke-Chambour

    Citation: Respiratory Research 2020 21:25

    Content type: Research

    Published on:

    The Correction to this article has been published in Respiratory Research 2020 21:29

  17. Acute respiratory distress syndrome (ARDS), a complex response to various insults, has a high mortality rate. As pulmonary edema resulting from increased vascular permeability is a hallmark of ARDS, management...

    Authors: Yanfei Shen, Guolong Cai, Shangzhong Chen, Caibao Hu and Jing Yan

    Citation: Respiratory Research 2020 21:24

    Content type: Research

    Published on:

  18. The aim of this study is investigating the benefits and harms of neuromuscular blocking agents (NMBAs) in patients with acute respiratory distress syndrome (ARDS).

    Authors: Zhongjun Zheng, Libing Jiang, Song Zhang, Christophe Guervilly, Mao Zhang, Xia Feng and Jianbo Ding

    Citation: Respiratory Research 2020 21:23

    Content type: Research

    Published on:

  19. Airway remodeling consists of the structural changes of airway walls, which is often considered the result of longstanding airway inflammation, but it may be present to an equivalent degree in the airways of c...

    Authors: Jun-xia Jiang, Hui-juan Shen, Yan Guan, Yong-liang Jia, Jian Shen, Qi Liu, Qiang-min Xie and Xiao-feng Yan

    Citation: Respiratory Research 2020 21:22

    Content type: Research

    Published on:

  20. For still unclear reasons, chronic airway infection often occurs in patients with Chronic Obstructive Pulmonary Disease (COPD), particularly in those with more severe airflow limitation. Fatty-acid binding pro...

    Authors: Lídia Perea, Ana Rodrigo-Troyano, Elisabet Cantó, Marisol Domínguez-Álvarez, Jordi Giner, Ferran Sanchez-Reus, Judit Villar-García, Sara Quero, Marian García-Núñez, Alicia Marín, Eduard Monsó, Rosa Faner, Alvar Agustí, Silvia Vidal and Oriol Sibila

    Citation: Respiratory Research 2020 21:21

    Content type: Research

    Published on:

  21. The use of extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplantation has greatly increased. However, data regarding the clinical outcomes of this approach are lacking. The objective of thi...

    Authors: Ryoung-Eun Ko, Jin Gu Lee, Song Yee Kim, Young Tae Kim, Sun Mi Choi, Do Hyung Kim, Woo Hyun Cho, Seung-Il Park, Kyung-Wook Jo, Hong Kwan Kim, Hyo Chae Paik and Kyeongman Jeon

    Citation: Respiratory Research 2020 21:20

    Content type: Research

    Published on:

  22. Diagnosing and treating asthma in paediatric patients remains challenging, with many children and adolescents remaining uncontrolled despite treatment. Selecting the most appropriate pharmacological treatment ...

    Authors: Christian Vogelberg, Stanley Goldstein, LeRoy Graham, Alan Kaplan, Alberto de la Hoz and Eckard Hamelmann

    Citation: Respiratory Research 2020 21:19

    Content type: Research

    Published on:

  23. Recurrent bronchiectasis exacerbations are related to deterioration of lung function, progression of the disease, impairment of quality of life, and to an increased mortality. Improved detection of exacerbatio...

    Authors: Amaia Artaraz, Megan L. Crichton, Simon Finch, Hani Abo-Leyah, Pieter Goeminne, Stefano Aliberti, Thomas Fardon and James D. Chalmers

    Citation: Respiratory Research 2020 21:18

    Content type: Research

    Published on:

  24. Clinically Important Deterioration (CID) is a novel composite measure to assess treatment effect in chronic obstructive pulmonary disease (COPD). We examined the performance and utility of CID in assessing the...

    Authors: Mona Bafadhel, Dave Singh, Christine Jenkins, Stefan Peterson, Thomas Bengtsson, Peter Wessman and Malin Fagerås

    Citation: Respiratory Research 2020 21:17

    Content type: Research

    Published on:

  25. Lung–protective ventilation (LPV) has been found to minimize the risk of ventilator–induced lung injury (VILI). However, whether LPV is able to diminish ventilator–induced diaphragm dysfunction (VIDD) remains ...

    Authors: Xian-Long Zhou, Xiao-Jun Wei, Shao-Ping Li, Hao-Li Ma and Yan Zhao

    Citation: Respiratory Research 2020 21:16

    Content type: Research

    Published on:

  26. Blood eosinophils are a predictive biomarker of inhaled corticosteroid response in chronic obstructive pulmonary disease (COPD). We investigated blood eosinophil stability over 1 year using the Global Initiati...

    Authors: Gabriella H. Long, Thomas Southworth, Umme Kolsum, Gavin C. Donaldson, Jadwiga A. Wedzicha, Christopher E. Brightling and Dave Singh

    Citation: Respiratory Research 2020 21:15

    Content type: Letter to the Editor

    Published on:

  27. Asthma is a heterogeneous disease characterized by chronic airway inflammation. Long non-coding RNA can act as competing endogenous RNA to mRNA, and play significant role in many diseases. However, there is li...

    Authors: Yifang Liao, Ping Li, Yanxia Wang, Hong Chen, Shangwei Ning and Dongju Su

    Citation: Respiratory Research 2020 21:14

    Content type: Research

    Published on:

  28. This study aims to evaluate the impact of diffusing capacity of the lung for carbon monoxide (DLco) before and after neoadjuvant concurrent chemoradiotherapy (CCRT) on postoperative pulmonary complication (PPC...

    Authors: Sumin Shin, Yong Soo Choi, Jae Jun Jung, Yunjoo Im, Sun Hye Shin, Danbee Kang, Jong Ho Cho, Hong Kwan Kim, Jhingook Kim, Jae Ill Zo, Young Mog Shim, Keunchil Park, Myung-Ju Ahn, Yong Chan Ahn, Genehee Lee, Juhee Cho…

    Citation: Respiratory Research 2020 21:13

    Content type: Research

    Published on:

  29. Chronic Hypersensitivity Pneumonitis (cHP) is a fibrotic interstitial lung disease (ILD) resulting from repeated exposure to an offending antigen. Prognostication in cHP remains challenging, and the relationsh...

    Authors: Julia Wälscher, Benjamin Gross, Julie Morisset, Kerri A. Johannson, Martina Vasakova, Jacques Bruhwyler and Michael Kreuter

    Citation: Respiratory Research 2020 21:12

    Content type: Research

    Published on:

  30. Several registries of idiopathic pulmonary fibrosis (IPF) have been established to better understand its natural history, though their size and duration of follow-up are limited. Here, we describe the large Eu...

    Authors: Tanja Tran, Martina Šterclová, Nesrin Mogulkoc, Katarzyna Lewandowska, Veronika Müller, Marta Hájková, Mordechai R. Kramer, Dragana Jovanović, Jasna Tekavec-Trkanjec, Michael Studnicka, Natalia Stoeva, Karel Hejduk, Ladislav Dušek, Samy Suissa and Martina Vašáková

    Citation: Respiratory Research 2020 21:11

    Content type: Research

    Published on:

  31. Although cavities are an important finding in Mycobacterium avium complex pulmonary disease (MAC-PD), there is little information regarding the types of cavities that indicate disease progression. This study was ...

    Authors: Yohei Oshitani, Seigo Kitada, Ryuya Edahiro, Kazuyuki Tsujino, Hiroyuki Kagawa, Kenji Yoshimura, Keisuke Miki, Mari Miki and Hiroshi Kida

    Citation: Respiratory Research 2020 21:10

    Content type: Research

    Published on:

  32. High prevalence of obstructive sleep apnea (OSA) in the pulmonary hypertension (PH) population suggests that chronic intermittent hypoxia (CIH) is an important pathogenic factor of PH. However, the exact mecha...

    Authors: Cuiping Fu, Shengyu Hao, Zilong Liu, Liang Xie, Xu Wu, Xiaodan Wu and Shanqun Li

    Citation: Respiratory Research 2020 21:9

    Content type: Research

    Published on:

  33. While porcine seems to be superior to bovine surfactants in terms of respiratory outcomes, it is unclear if a surfactant can improve extra-pulmonary outcomes in preterm neonates with respiratory distress syndr...

    Authors: Silvia Foligno and Daniele De Luca

    Citation: Respiratory Research 2020 21:8

    Content type: Research

    Published on:

  34. The approvals of nintedanib and pirfenidone changed the treatment paradigm in idiopathic pulmonary fibrosis (IPF), and increased our understanding of the underlying disease mechanisms. Nonetheless, many challe...

    Authors: Claudia Valenzuela, Sebastiano Emanuele Torrisi, Nicolas Kahn, Manuel Quaresma, Susanne Stowasser and Michael Kreuter

    Citation: Respiratory Research 2020 21:7

    Content type: Review

    Published on:

  35. Serum chitotriosidase is a promising biomarker that has shown high specificity and sensitivity in patients with sarcoidosis. The aim of this study was to investigate correlations between serum chitotriosidase,...

    Authors: David Bennett, Paolo Cameli, Nicola Lanzarone, Loredana Carobene, Nicola Bianchi, Annalisa Fui, Luigi Rizzi, Laura Bergantini, Giuseppe Cillis, Miriana d’Alessandro, Maria Antonietta Mazzei, Rosa Metella Refini, Piersante Sestini, Elena Bargagli and Paola Rottoli

    Citation: Respiratory Research 2020 21:6

    Content type: Research

    Published on:

    The Correction to this article has been published in Respiratory Research 2020 21:34

  36. Antibiotics are overused in patients with acute lower respiratory tract infections (ALRTIs), but less is known about their use in patients with asthma, or the use of asthma medication for ALRTI in patients wit...

    Authors: Rachel Denholm, Esther T. van der Werf and Alastair D. Hay

    Citation: Respiratory Research 2020 21:4

    Content type: Research

    Published on:

  37. Blood eosinophil count has been proposed as a predictor of response to inhaled corticosteroid (ICS) in the prevention of acute exacerbations of COPD. An optimal threshold of blood eosinophil count for prescrib...

    Authors: Timothy H. Harries, Victoria Rowland, Christopher J. Corrigan, Iain J. Marshall, Lucy McDonnell, Vibhore Prasad, Peter Schofield, David Armstrong and Patrick White

    Citation: Respiratory Research 2020 21:3

    Content type: Research

    Published on:

  38. Idiopathic pulmonary fibrosis (IPF) is a fatal disease that results in poor quality of life due to progressive respiratory symptoms, anxiety, and depression. Palliative care improves quality of life and surviv...

    Authors: Katherine Janssen, Drew Rosielle, Qi Wang and Hyun Joo Kim

    Citation: Respiratory Research 2020 21:2

    Content type: Research

    Published on:

  39. To observe the efficacy of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) for pulmonary alveolar proteinosis (PAP).

    Authors: Fen Zhang, Dong Weng, Yiliang Su, Chengsheng Yin, Li Shen, Yuan Zhang, Ying Zhou, Qiuhong Li, Yang Hu and Huiping Li

    Citation: Respiratory Research 2020 21:1

    Content type: Research

    Published on:

  40. Ventilator-induced diaphragmatic dysfunction is a serious complication associated with higher ICU mortality, prolonged mechanical ventilation, and unsuccessful withdrawal from mechanical ventilation. Although ...

    Authors: Tatsutoshi Shimatani, Nobuaki Shime, Tomohiko Nakamura, Shinichiro Ohshimo, Justin Hotz and Robinder G. Khemani

    Citation: Respiratory Research 2019 20:293

    Content type: Research

    Published on:

  41. In the embryonic mammalian lung, mesenchymal cells act both as a signaling center for epithelial proliferation, differentiation and morphogenesis as well as a source for a multitude of differentiated cell type...

    Authors: Irina Wojahn, Timo H. Lüdtke, Vincent M. Christoffels, Mark-Oliver Trowe and Andreas Kispert

    Citation: Respiratory Research 2019 20:292

    Content type: Research

    Published on:

  42. Low-resource settings are disproportionally burdened by chronic lung disease due to early childhood disadvantages and indoor/outdoor air pollution. However, data on the socioeconomic impact of respiratory dise...

    Authors: Evelyn A. Brakema, Aizhamal Tabyshova, Rianne M. J. J. van der Kleij, Talant Sooronbaev, Christos Lionis, Marilena Anastasaki, Pham Le An, Luan Than Nguyen, Bruce Kirenga, Simon Walusimbi, Maarten J. Postma, Niels H. Chavannes and Job F. M. van Boven

    Citation: Respiratory Research 2019 20:291

    Content type: Research

    Published on:

  43. Several small molecule corrector and potentiator drugs have recently been licensed for Cystic Fibrosis (CF) therapy. However, other aspects of the disease, especially inflammation, are less effectively treated...

    Authors: Q. Yang, A. R. Soltis, G. Sukumar, X. Zhang, H. Caohuy, J. Freedy, C. L. Dalgard, M. D. Wilkerson, H. B. Pollard and B. S. Pollard

    Citation: Respiratory Research 2019 20:290

    Content type: Research

    Published on:

  44. Increased numbers of blood and sputum eosinophils are associated with higher exacerbation frequency and increased asthma severity. In clinical trials, targeting Interleukin-5 has been shown to be a useful ther...

    Authors: H. Ibrahim, R. O’Sullivan, D. Casey, J. Murphy, J. MacSharry, B. J. Plant and D. M. Murphy

    Citation: Respiratory Research 2019 20:289

    Content type: Letter to the Editor

    Published on:

  45. Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection during childhood may polarise the immune system towards...

    Authors: Brian R. Leaker, Dave Singh, Sam Lindgren, Gun Almqvist, Leif Eriksson, Barbara Young and Brian O’Connor

    Citation: Respiratory Research 2019 20:288

    Content type: Research

    Published on:

  46. Acute exacerbation of chronic fibrosing idiopathic interstitial pneumonias (AE-IIPs) is associated with a high mortality rate. In 2016, an international working group proposed a revised diagnostic criteria for...

    Authors: Motoyasu Kato, Tomoko Yamada, Shunichi Kataoka, Yuta Arai, Keita Miura, Yusuke Ochi, Hiroaki Ihara, Ryo Koyama, Shinichi Sasaki and Kazuhisa Takahashi

    Citation: Respiratory Research 2019 20:287

    Content type: Research

    Published on:

  47. Macrolide is a key drug in the treatment of Mycobacterium avium complex pulmonary disease (MAC-PD). Macrolide-resistant MAC is gaining importance, but there are little data in clinical characteristics and treatme...

    Authors: Youngmok Park, Eun Hye Lee, Inkyung Jung, Goeun Park and Young Ae Kang

    Citation: Respiratory Research 2019 20:286

    Content type: Research

    Published on:

  48. β2 receptor agonists induce airway smooth muscle relaxation by increasing intracellular cAMP production. PKA is the traditional downstream signaling pathway of cAMP. Exchange protein directly activated by cAMP (....

    Authors: Yi-fei Chen, Ge Huang, Yi-min Wang, Ming Cheng, Fang-fang Zhu, Jin-nan Zhong and Ya-dong Gao

    Citation: Respiratory Research 2019 20:285

    Content type: Research

    Published on:

  49. Bacteria have been extensively implicated in the development of smoking related diseases, such as COPD, by either direct infection or bacteria-mediated inflammation. In response to the health risks associated ...

    Authors: Deirdre F. Gilpin, Katie-Ann McGown, Kevin Gallagher, Jose Bengoechea, Amy Dumigan, Gisli Einarsson, J. Stuart Elborn and Michael M. Tunney

    Citation: Respiratory Research 2019 20:267

    Content type: Research

    Published on:

Annual Journal Metrics