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Retraction Note: Shp2 positively regulates cigarette smoke-induced epithelial mesenchymal transition by mediating MMP-9 production

The Original Article was published on 26 June 2020

Respiratory Research (2020) 21:161

https://doi.org/10.1186/s12931-020-01426-9

The Editors-in-Chief have retracted this article. Concerns with Fig. 6B were previously addressed with a correction [1] but more image irregularities have been identified, specifically:

Figure 2D: theShp(KO) + CS panel appears to partially overlap with the MK-2206 + CS MMP-9 panel of Fig. 2C in a previously published article [2].

Figure 5A: there appears to be a splice in the Pro-MMP-9 band.

Figure 7A: the JNK 1.25 and 2.5 blots appear to be identical to the JNK //- and +// blots in Fig. 7B.

The Editors-in-Chief therefore no longer have confidence in the results reported in this article.

Authors Ya-nan Liu Jian Shen, Jian-cang Zhou, Hui-juan Shen, Qiang Shu, Qiang-min Xie and Yicheng Xie agree with this retraction. The other authors have not responded to correspondence regarding this retraction.

References

  1. Liu Y, Guan Y, Shen J, et al. Correction to: Shp2 positively regulates cigarette smoke-induced epithelial mesenchymal transition by mediating MMP-9 production. Respir Res. 2022;23:217. https://doi.org/10.1186/s12931-022-02121-7.

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  2. Jiang B, Guan Y, Shen Hui-juan, Zhang Lin-hui. Jun-xia Jiang, Xin-wei Dong, Hua-hao Shen, Qiang-min Xie, Akt/PKB signaling regulates cigarette smoke-induced pulmonary epithelial-mesenchymal transition, Lung Cancer, Volume 122, 2018, Pages 44–53, https://doi.org/10.1016/j.lungcan.2018.05.019.

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Correspondence to Qiang-min Xie or Yicheng Xie.

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Liu, Yn., Guan, Y., Shen, J. et al. Retraction Note: Shp2 positively regulates cigarette smoke-induced epithelial mesenchymal transition by mediating MMP-9 production. Respir Res 24, 200 (2023). https://doi.org/10.1186/s12931-023-02506-2

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  • DOI: https://doi.org/10.1186/s12931-023-02506-2