Table 1 Patients’ characteristics for analysis of LILRB4 expression on human lung macrophages
Characteristics | Never-smokers (n = 21) | Non-COPD smokers (n = 16) | COPD (n = 14) | P value |
|---|---|---|---|---|
Age (years) | 68.5 ± 8.7 | 67.6 ± 5.5 | 75.5 ± 3.7 |  < 0.001 |
Male/female | 3/18 | 13/3 | 13/1 |  < 0.0001 |
Smoking (pack-years) | 0 | 39.6 ± 29.2 | 48.4 ± 32.0 |  < 0.0001 |
FVC (L) | 2.8 ± 0.7 | 3.2 ± 0.9 | 3.2 ± 0.5 | 0.017 |
FEV1 (L) | 2.2 ± 0.6 | 2.6 ± 0.4 | 2.1 ± 0.3 | 0.004 |
FEV1/FVC (%) | 83.9 ± 6.2 | 95.9 ± 11.0 | 63.5 ± 5.7 |  < 0.0001 |
FEV1 (% of predicted value) | 108.5 ± 19.3 | 91.5 ± 8.6 | 82.6 ± 9.4 |  < 0.0001 |
% DLCO | 97.1 ± 17.2 | 86.4 ± 19.5 | 93.1 ± 33.6 | N.S |
% DLCO/VA (% predicted value) | 103.7 ± 16.3 | 93.5 ± 28.9 | 79.7 ± 23.4 | N.S |
GOLD stage (I/II) | – | – | 11/3 |  |