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Table 3 Compilation of the cell-specific immunohistochemical results and demographic associations

From: Smoking-associated increase in mucins 1 and 4 in human airways

Factor

Airway cell phenotype

Demographic association

MUC1

Basal cell

↑ Smokers and Chronic bronchitis

Correlated negatively with lung functions in male Smokers

Correlated positively with pack-years

MUC4

Goblet cells

↑ Smokers

EGFR1

Basal cells

No change

EGFR2

Basal and ciliated cells

↑ Healthy

Correlated positively with lung functions

Correlated negatively with pack-years and current cigarette consumption

  1. Alterations in abundance are expressed in comparison to the healthy Never-smoker group