Fig. 9
From: Complementary roles of KCa3.1 channels and β1-integrin during alveolar epithelial repair
Complementary roles of ECM, β1-integrin, KCa3.1 and TRPC4 channels during alveolar repair process. The presence of fibronectin matrix evokes an increase in membrane expression of β1-integrin, KCa3.1 and TRPC4, an elevation of steady-state [Ca2+]i and a stimulation of ATII wound healing. This stimulation is dependent, at least in part on KCa3.1 and TRPC4 channel activity. Our data also highlighted a relationship between KCa3.1 and β1-integrin