Magnetic resonance lung function – a breakthrough for lung imaging and functional assessment? A phantom study and clinical trial

Table 2 MRI ventilation measurements.

Lung region/Diagnosis	All patients	Healthy	Asthma	CF
Right upper field (ml/ml)	0.38 ± 0.15	0.52 ± 0.18	0.43 ± 0.14	0.31 ± 0.13
Right middle field (ml/ml)	0.39 ± 0.14	0.53 ± 0.16	0.44 ± 0.13	0.32 ± 0.12
Right lower field (ml/ml)	0.41 ± 0.14	0.62 ± 0.10	0.45 ± 0.14	0.35 ± 0.12
Left upper field (ml/ml)	0.37 ± 0.15	0.50 ± 0.14	0.42 ± 0.15	0.31 ± 0.13
Left middle field (ml/ml)	0.38 ± 0.13	0.51 ± 0.18	0.41 ± 0.13	0.33 ± 0.10
Left lower field (ml/ml)	0.41 ± 0.14	0.65 ± 0.11	0.43 ± 0.13	0.36 ± 0.11
Mean (ml/ml)	0.39 ± 0.13	0.55 ± 0.12	0.43 ± 0.13	0.33 ± 0.11
Mean FVC (%)	81 ± 18	93 ± 13	89 ± 12	67 ± 11
Mean VC (%)	80 ± 18	93 ± 13	87 ± 13	67 ± 20

Measurement of the local ventilation in 6 ROIs by MRI. The ventilation is given as ml air per ml lung parenchyma. Note the differences of local ventilation for different groups of patients. For comparison FVC and VC of the conventional pulmonary function test. FVC% = forced vital capacity in % of the expected. VC (%) = vital capacity in % of the expected.

ISSN: 1465-993X