Table 4 Effects of asthma status on baseline (Mock) and RV-induced cytokine secretion and interferon mRNA expression (geometric mean, 95% CI)
From: Budesonide and formoterol effects on rhinovirus replication and epithelial cell cytokine responses
Cytokine | Normal | Asthma | P value (asthma vs. normal) | |
|---|---|---|---|---|
CXCL10 (pg/mL) | Mock | 3.4 (2.2, 5.1) | 5.3 (3.5, 8.2) | 0.06 |
RV | 50.6 (21.6, 118.1)** | 10.1 (4.2, 24.4) | 0.003 | |
TNFα (pg/mL) | Mock | 3.2 (1.3, 7.9) | 1.4 (0.6, 3.5) | 0.02 |
RV | 4.7 (1.9, 11.3)* | 1.4 (0,6, 3.5) | 0.0003 | |
IFNB1 mRNA (fold increase) | 3.4 (2.2, 5.3) | 1.5 (1.0, 2.5) | 0.01 | |
IL28 mRNA (fold increase) | 49 (21, 112) | 9.2 (3.8, 22) | 0.009 | |