Fig. 4
From: PI3Kγδ inhibition suppresses key disease features in a rat model of asthma
PI3Kγδ inhibitor, AZD8154, suppresses eosinophilia and neutrophilia in BAL. The impact of AZD8154 and budesonide on airways inflammation in BAL fluid collected 24 hours after antigen (OVA) challenge in respect to total leukocytes (A), neutrophils (B), eosinophils (C) was assessed. Data are presented as boxes (Q2 to Q3 with the median) and whiskers (min to max). Statistically significant differences between Saline/Vehicle and other groups as presented as **p < 0.01; statistically significant differences between OVA/Vehicle and other groups are presented as #p < 0.05, ##p < 0.01 & ###p < 0.001. One experiment (n = 7–8)