Fig. 5From: Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosisConcentrations of EV proteins in patients with sarcoidosis treated with methotrexate of the replication cohort (n = 82), measured in different EV fractions as well as in whole serum. Figure (a) represents concentrations of Serpin C1 in the LDL fraction; figure (b) concentrations of CD14 in the LDL fraction, and figure (c) concentrations of cystatin C in the HDL fraction in non-responders and responders to treatment with methotrexate. Serpin C1 concentrations were significantly higher in non-responders than in responders (p = 0.032). Black filled squares represent non-responders (NR) and gray open squares represent responders (R) to treatment with methotrexate. *p < 0.05Back to article page