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Table 1 Characteristics of the subjects in the study

From: TFEB regulates dendritic cell antigen presentation to modulate immune balance in asthma

 

Healthy (n = 15)

Asthma (n = 23)

p Value

Sex (M/F)

10/5

14/9

0.7261

Age (yrs)

7.36 (0.4140)

6.56 (0.3021)

0.1197

BMI (kg/m²)

17.74 (1.005)

15.68 (0.5245)

0.0548

Serum total IgE level (IU/mL)

73.52 (15.80)

811.3 (167.1)

0.0026

Allergen-specific IgE (kU/L)

0.09556 (0.0632)

30.11 (7.609)

0.0124

Allergens, n(%)

2 (13.33%)

17 (73.91%)

< 0.0001

Dust mite

0 (0.00%)

12 (52.17%)

0.0004

Cat

0 (0.00%)

2 (8.70%)

0.2067

Egg white

1 (6.67%)

1 (4.35%)

0.8679

Others

1 (6.67%)

2 (8.70%)

0.7042

Second-hand smoke, n (%)

6 (40.00%)

17 (73.91%)

0.0373

Familial allergy, n (%)

2 (13.33%)

16 (69.57%)

< 0.0001

Familial asthma, n (%)

0 (0.00%)

8 (34.78%)

0.0031

FEV1 (%pred)

102.71 (2.261)

91.13 (1.998)

0.0006

FVC (%pred)

96.86 (2.369)

97.87 (1.542)

0.7118

FEV1/FVC

Age of asthma onset, n (%)

105.89 (1.249)

93.14 (1.866)

< 0.0001

  1. Data presented as mean(SEM) and count (percentage); Definition of abbreviations: BMI = Body mass index, IgE immunoglobulin E, FEV1 = Forced expiratory volume in 1 s, FVC = Forced Vital Capacity; P < 0.05 was statistically significant