Table 1 Baseline characteristics in the overall population and success and failure SBT subgroups
Total Population (n = 23) | Successful SBT (n = 18) | Failed SBT (n = 5) | p-value | |
|---|---|---|---|---|
Gender (M/F) | M:14, F:9 | M:12, F:6 | M:2 F:3 | |
BMI (kg/m2) | 27.8 (5.8) | 26.7 (5.3) | 31.6 (6.6) | 0.1 |
Age (years) | 63 [57.5 70] | 62.5 [57.2 67.2] | 70 [69 73] | 0.26 |
SAPS II | 39.8 (16.6) | 36.2 (13.3) | 52.8 (22.3) | < 0.05 |
SOFA at study enrolment | 4.9 (2.6) | 4.9 (2.9) | 4.8 (1.3) | 0.95 |
Days ventilated before study (days) | 11.3 (5.8) | 10.7 (5.9) | 13.4 (5.0) | 0.37 |
Total ventilation duration (days) | 15.3 (8.5) | 12.4 (5.9) | 25.6 (8.7) | < 0.05 |
Pressure support ventilation before SBT (days) | 3 [2 7] | 3.5 [2 7] | 3 [2 6] | 0.51 |
SBT length (min) | 31 [24.5 35.5] | 33 [30.2 35.8] | 15 [9 21] | < 0.05 |
ICU length-of-stay (days) | 19.3 (10.7) | 15.7 (7.4) | 32.3 (11.8) | < 0.05 |
ICU mortality | 2 | 1 | 1 | |
Admission diagnosis (n, %) | ||||
Respiratory | 10 (43%) | 7 (39%) | 3 (60%) | |
Neurological | 6 (26%) | 6 (33%) | 0 (0%) | |
Cardiovascular | 3 (13%) | 2 (11%) | 1 (20%) | |
Trauma | 3 (13%) | 2 (11%) | 1 (20%) | |
Sepsis | 1 (4%) | 1 (6%) | 0 (0%) | |
Respiratory mechanics at study baseline (clinical settings) | ||||
Total PEEP (cmH2O) | 7.5 (2.1) | 7.3 (1.8) | 8.4 (3.2) | 0.50 |
dP (cmH2O) | 8.1 (3.2) | 7.8 (3.2) | 9.2 (3.5) | 0.44 |
PaO2 before the SBT (mmHg) | 84.8 (20.3) | 86.3 (21.8) | 79.6 (15.8) | 0.45 |
PaO2 after the SBT (mmHg) | 95.3 (36.8) | 102.8 (36.8) | 68.3 (23.3) | < 0.05 |
PaCO2 before the SBT (mmHg) | 41.3 (5.3) | 41.3 (6.0) | 42.0 (3.8) | 0.66 |
PaCO2 after the SBT (mmHg) | 40.5 (6.0) | 39.8 (5.3) | 42.8 (9.0) | 0.49 |
RSBI before the SBT | 40.1 [32.1 53.9] | 37.8 [31.5 48.8] | 53.7 [53.3 59.5] | 0.18 |
P/F ratio before the SBT | 232 [205.5 303.5] | 231 [207 318] | 233 [188 279] | 0.39 |
FiO2 (%) | 35 [30 40] | 35 [30 38.8] | 35 [35 40] | 0.48 |