Table 4 Univariate analyses of the predictive factors of outcome (death or lung transplantation)

Demographic data

 Age at onset of symptoms, mean

0.945

0.904—0.988

0.013

 Age at diagnosis, mean

0.942

0.902—0.983

0.0057

 Sex

0.714

0.435—1.169

0.18

 Smoking status

0.955

0.352—2.587

0.93

Lung function parameters

 FEV1, % pred

0.974

0.955—0.994

0.012

 FVC, % pred

0.985

0.962 -1.01

0.21

 FEV1/FVC, %

0.942

0.903—0.982

0.005

 TLC, % pred

1.023

0.989—0.982

0.19

 DLCO, % pred

0.971

0.942—1.002

0.06

 KCO, % pred

0.980

0.945—1.015

0.26

 6-min walk test, m

0.995

0.987 – 1.003

0.21

 Mean ∆FEV1, ml/year

1.007

1.003 – 1.011

0.00095

 Mean ∆DLCO, %/year

1.039

0.827 – 1.305

0.75

Serum light chains

 Mean kappa light chain in serum, mg/L

1.001

0.999 – 1.002

0.30

 Mean lambda light chain in serum, mg/L

1.016

0.898 – 1.150

0.80

 Mean serum kappa/lambda ratio

1.008

0.997 – 1.019

0.14

Predominant pattern (cystic/bronchiectasis)

0.491

0.226 – 1.069

0.07