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Table 2 List of the 10 most significantly regulated genes following carboplatin-gemcitabine treatment

From: Use of non-small cell lung cancer multicellular tumor spheroids to study the impact of chemotherapy

Gene

Log2 fold change

P value

Adjusted p value

SUGCT

4.43

5.16e-57

2.87e-53

GDF15

3.72

5.96e-49

1.88e-45

C1QTNF1-AS1

3.52

4.48e-35

7.12e-32

TIMP1

2.74

2.32e-113

2.59e-109

CDKN1A

2.55

6.77e-49

1.88e-45

DDIT3

2.18

3.84e-34

4.75e-31

NEK6

−1.65

2.68e-34

3.73e-31

PLAC8

−2.39

7.88e-34

8.77e-31

CCNB1

−2.67

6.85e-39

1.52e-35

CENPF

−2.8

6.26e-37

1.16e-33