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Table 1 Characteristics of participants according to BMI change

From: Longitudinal BMI change and outcomes in Chronic Obstructive Pulmonary Disease: a nationwide population-based cohort study

 

Over 5% decrease

Maintenance

Over 5% increase

p value

N = 14,728

N = 80,689

N = 21,046

Age, years

69.5 (10.5)

67.2 (9.9)

67.4 (10.2)

< 0.001

Sex

   

< 0.001

Male

9,405 (63.9)

54,231 (67.2)

13,646 (64.8)

 

Female

5,323 (36.1)

26,458 (32.8)

7,400 (35.2)

 

Residential area, metropolitan

7,172 (48.7)

43,204 (53.5)

10,893 (51.8)

< 0.001

Income

   

< 0.001

Medical Aid

773 (5.2)

2,664 (3.3)

1,180 (5.6)

 

≤ 30th

3,212 (21.8)

17,743 (22.0)

4,665 (22.2)

 

31st – 70th

4,799 (32.6)

26,250 (32.5)

6,888 (32.7)

 

> 70th

5,721 (38.8)

32,712 (40.5)

7,986 (37.9)

 

Unknown

223 (1.5)

1,320 (1.6)

327 (1.6)

 

BMI before COPD diagnosis

24.3 (3.7)

24.1 (3.3)

22.9 (3.4)

< 0.001

Underweight

677 (4.6)

3,122 (3.9)

1,746 (8.3)

 

Normal

4,853 (33.0)

26,868 (33.3)

9,565 (45.4)

 

Overweight

3,379 (22.9)

20,425 (25.3)

4,666 (22.2)

 

Obese

5,819 (39.5)

30,274 (37.5)

5,069 (24.1)

 

BMI after COPD diagnosis

22.2 (3.4)

24.2 (3.4)

24.9 (3.7)

< 0.001

Underweight

1,987 (13.5)

3,181 (3.9)

482 (2.3)

 

Normal

7,031 (47.7)

26,473 (32.8)

5,916 (28.1)

 

Overweight

2,939 (20.0)

20,246 (25.1)

4,997 (23.7)

 

Obese

2,771 (18.8)

30,789 (38.2)

9,651 (45.9)

 

Smoking status

   

< 0.001

Never

6,551 (44.5)

33,075 (41.0)

8,711 (41.4)

 

Past

2,968 (20.2)

19,352 (24.0)

5,585 (26.5)

 

Current

3,107 (21.1)

16,393 (20.3)

3,719 (17.7)

 

Unknown

2,102 (14.3)

11,869 (14.7)

3,031 (14.4)

 

Drinking status

   

< 0.001

No

10,338 (70.2)

50,087 (62.1)

13,570 (64.5)

 

Yes

4,387 (29.8)

30,562 (37.9)

7,470 (35.5)

 

Unknown

3 (0.0)

40 (0.0)

6 (0.0)

 

Regular MVPA, yes

3,199 (21.7)

19,445 (24.1)

4,493 (21.3)

< 0.001

Charlson Comorbidity Indexa)

2.4 (1.9)

2.1 (1.7)

2.2 (1.7)

< 0.001

Comorbiditiesa)

    

Pulmonary TB

613 (4.2)

2,508 (3.1)

834 (4.0)

< 0.001

ILD

409 (2.8)

1,589 (2.0)

385 (1.8)

< 0.001

Bronchiectasis

950 (6.5)

4,978 (6.2)

1,256 (6.0)

0.175

Pneumonia

3,081 (20.9)

14,066 (17.4)

3,835 (18.2)

< 0.001

Medicationa)

    

LABA

2,027 (13.8)

11,228 (13.9)

3,058 (14.5)

0.048

LAMA

2,619 (17.8)

13,333 (16.5)

3,806 (18.1)

< 0.001

ICS

3,059 (20.8)

14,545 (18.0)

4,003 (19.0)

< 0.001

Previous severe exacerbationa)

1,450 (9.8)

5,311 (6.6)

1,635 (7.8)

< 0.001

  1. Values were presented as n (%) or mean (SD)
  2. a) Values were assessed within 1 year before Exam 2 (baseline)
  3. BMI, body mass index; MVPA, moderate-to-vigorous physical activity; ICS, inhaled corticosteroid; LABA, long-acting beta-2 agonist; LAMA, long-acting muscarinic agonist; TB, tuberculosis; ILD, interstitial lung disease; SD, standard deviation