Table 2 Comparison between different lung function
From: Neopterin in patients with COPD, asthma, and ACO: association with endothelial and lung functions
I (n = 30) | I(n = 17) | III (n = 23) | IVn = 7) | P value | |
|---|---|---|---|---|---|
Age | 55.4 ± 8.9 | 55.1 ± 6.6 | 58.0 ± 9.3 | 59.4 ± 3.6 | 0.445 |
Male | 20 (67) | 14 (82) | 19 (83) | 7 (100) | 0.197 |
Height, m | 1.6 ± 0.1 | 1.7 ± 0.1 | 1.7 ± 0.1 | 1.7 ± 0.1 | 0.057 |
Weight, kg | 64.0 ± 8.5 | 62.5 ± 6.8 | 62.9 ± 11.9 | 57.7 ± 13.1 | 0.500 |
BMI, kg/m2 | 24.0 ± 2.7 | 22.6 ± 2.6 | 22.3 ± 3.4 | 20.2 ± 4.5 | 0.022 |
SBP, mmHg | 126 ± 17 | 128 ± 18 | 134 ± 13 | 131 ± 17 | 0.357 |
DBP, mmHg | 77 ± 10 | 79 ± 10 | 83 ± 11 | 82 ± 11 | 0.178 |
Vascular evaluation | |||||
PWV, cm/s | 1524.5 ± 337.3 | 1664.6 ± 421.2 | 1667.0 ± 355.7 | 2037.7 ± 727.6 | 0.032 |
FMD (% ) | 7.1 ± 3.5 | 6.4 ± 2.5 | 5.5 ± 2.0 | 4.7 ± 2.5 | 0.095 |
Inflammatory markers | |||||
IL-10, pg/ml | 440.8 (382.4-556.4) | 445.7 (362.3-598.5) | 460.1 (387.0-571.1) | 456.2 (448.3-535.8) | 0.847 |
IL-17, pg/ml | 21.1 (11.8–35.4) | 4.3 (0.0-51.8) | 12.9 (3.1–44.0) | 12.0 (6.4–16.0) | 0.497 |
IL-6, pg/ml | 30.7 (20.5–56.1) | 29.2 (18.9–36.2) | 23.1 (18.4–38.3) | 34.1 (19.4–67.3) | 0.701 |
NP, nmol/l | 6.7 ± 2.6 | 8.5 ± 2.9 | 8.3 ± 2.4 | 8.9 ± 3.5 | 0.043 |