Table 3 GLI reference equations for spirometry in males and females of the LEAD cohort
From: Updated reference values for static lung volumes from a healthy population in Austria
Male ( n = 2397) | Female ( n = 2974) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Z–score | KS p -value | 95% CI | % > ULN | % < LLN | Z–score | KS p -value | 95% CI | % > ULN | % < LLN | |
(mean ± SD) | (mean ± SD) | |||||||||
FEV1 | ||||||||||
total | -0.03 ± 0.97 | 0.024 | [-0.07, -0.01] | 4.26 | 4.71 | 0.07 ± 0.99 | < 0.001 | [0.04, 0.11] | 6.15 | 3.97 |
≤ 18 years | 0.13 ± 1.00 | 0.001 | [0.06, 0.19] | 6.39 | 4.00 | 0.19 ± 1.04 | < 0.001 | [0.13, 0.25] | 9.14 | 3.77 |
18–65 years | -0.19 ± 0.92 | < 0.001 | [-0.24, -0.14] | 2.51 | 5.73 | -0.09 ± 0.92 | < 0.001 | [-0.14, -0.04] | 2.75 | 4.63 |
> 65 years | 0.24 ± 0.92 | 0.016 | [0.11, 0.36] | 5.56 | 1.52 | 0.51 ± 0.90 | < 0.001 | [0.40, 0.63] | 11.81 | 0.84 |
FVC | ||||||||||
total | -0.02 ± 0.96 | 0.04 | [-0.06, 0.02] | 3.55 | 4.71 | 0.10 ± 0.96 | < 0.001 | [0.07, 0.14] | 5.08 | 3.73 |
≤ 18 years | 0.12 ± 1.00 | 0.001 | [0.06, 0.18] | 5.19 | 3.68 | 0.23 ± 1.02 | < 0.001 | [0.18, 0.29] | 7.70 | 3.93 |
18–65 years | -0.15 ± 0.92 | < 0.001 | [-0.20, -0.10] | 1.96 | 5.88 | -0.06 ± 0.90 | < 0.001 | [-0.11, -0.02] | 2.48 | 4.09 |
> 65 years | 0.20 ± 0.91 | 0.008 | [0.07, 0.33] | 6.06 | 2.02 | 0.43 ± 0.81 | < 0.001 | [0.32, 0.53] | 7.59 | 0.42 |
FEV1/FVC | ||||||||||
total | -0.03 ± 0.98 | 0.002 | [-0.07, 0.01] | 4.92 | 4.63 | -0.07 ± 0.97 | < 0.001 | [-0.10, -0.03] | 5.52 | 4.84 |
≤ 18 years | 0.01 ± 1.01 | 0.4 | [-0.06, 0.07] | 5.84 | 4.33 | -0.11 ± 0.99 | < 0.001 | [-0.16, -0.05] | 5.53 | 5.37 |
18–65 years | -0.07 ± 1.00 | < 0.001 | [-0.13, -0.02] | 4.86 | 5.25 | -0.05 ± 0.98 | < 0.001 | [-0.10, 0.00] | 6.24 | 4.90 |
> 65 years | 0.03 ± 0.75 | 0.056 | [-0.08, 0.14] | 1.01 | 2.02 | 0.03 ± 0.74 | 0.003 | [-0.07, 0.12] | 0.84 | 1.69 |