Fig. 5
From: Loss of ZNF451 mediates fibroblast activation and promotes lung fibrosis
ZNF451 regulates the activation of lung fibroblasts. A Representative images of the migration assay for mouse PF lung fibroblasts with or without ZNF451 overexpression. Scale bars, 200 μm. B Immunoblots of α-SMA and Col1 in mouse PF lung fibroblasts with or without ZNF451 overexpression. C Representative images of the migration assay for mouse lung fibroblasts isolated from WT or Znf451-/- mice. Scale bars, 200 μm. D Immunoblots of α-SMA and Col1 in mouse lung fibroblasts isolated from WT or Znf451-/- mice. E Representative images of α-SMA immunostaining in mouse lung fibroblasts isolated from WT or Znf451-/- mice. Scale bars, 50 μm. F RT‒PCR of the mRNA expression of fibrosis genes in mouse lung fibroblasts isolated from WT or Znf451-/- mice