Fig. 7

AXT inhibited myofibroblast activation and proliferation via inhibits AKT

(A): Co-treatment of SC79 (Akt activitor, 10 µM) abolished the effect of AXT on expression of Collagen 1 and α-SMA; The alleviative effect of AXT on proliferation was reversed after application of SC79 in cigarette smoke extract(CSE)-treated MRC5 cells based on EdU (B) and CCK8 assays (C); *p < 0.05; **p < 0.01; ***p < 0.001