Table 3 The results of univariate and multivariate analysis of disease-free survival
Characteristics | Univariate | Multivariate | ||
|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Clinical factor | ||||
Age (per 1-year increase) | 1.00 (0.97–1.03) | 0.993 | 1.03 (1.00-1.06) | 0.057 |
Gender (Male as ref.) | 1.70 (0.87–3.33) | 0.120 | … | … |
Smoking status (Never as ref.) | 1.88 (0.86–4.11) | 0.112 | … | … |
Symptom (Absence as ref.) | 3.20 (1.69–6.07) | <0.001 | … | … |
CYFRA21-1 (Normal as ref.) | 4.14 (2.14–8.04) | <0.001 | … | … |
Surgery resection (No as ref.) | 0.15 (0.08–0.29) | <0.001 | 0.24 (0.11–0.55) | 0.001 |
Pathologic factor | ||||
T stage (T1/2 as ref.) | 2.42 (1.27–4.62) | 0.007 | … | … |
M stage (M0 as ref.) | 5.14 (2.37–11.13) | <0.001 | … | … |
Chest CT factor | ||||
Morphology (Round/oval as ref.) | 3.81 (1.33–10.94) | 0.013 | … | … |
Tumor site in lobe (Left as ref.) | 0.64 (0.34–1.22) | 0.176 | … | … |
Hilar and/or mediastinal LAP (Absence as ref.) | 5.55 (2.61–11.78) | <0.001 | 3.27 (1.39–7.70) | 0.007 |
Vascular encasement (Absence as ref.) | 1.34 (0.71–2.55) | 0.365 | … | … |
Necrosis (Absence as ref.) | 1.89 (0.90-4.00) | 0.095 | … | … |
Pleural and/or pericardial effusion (Absence as ref.) | 3.90 (1.51–10.06) | 0.005 | … | … |
CT value (<37.8 HU as ref.) | 3.14 (1.48–6.64) | 0.003 | 1.98 (0.92–4.26) | 0.079 |