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Table 2 Description of urinary DEHP metabolites comparisons between cases and controls, and among 6 phenotypic clusters and controls

From: Increased di-(2-ethylhexyl) phthalate exposure poses a differential risk for adult asthma clusters

Urinary metabolites (µg/g creatinine)

Control

 

Case

 

Cluster A

 

Cluster B

Median (IQR)

 

Median (IQR)

 

Median (IQR)

 

Median (IQR)

MEHP

5.48 (6.77)

 

8.74 (13.22)***

 

10.69 (10.40)

 

7.95 (8.92)

MEHHP

11.86 (11.34)

 

20.63 (21.38)***

 

25.93 (16.60)**

 

16.71 (13.44)

MEHP + MEHHP

18.20 (15.46)

 

30.73 (34.17)***

 

39.16 (35.26)**

 

26.35 (24.63)

MEHHP/MEHP

2.14 (2.20)

 

2.49 (2.55)

 

2.54 (3.82)

 

2.46 (2.02)

Urinary metabolites (µg/g creatinine)

Cluster C

 

Cluster D

 

Cluster E

 

Cluster F

Median (IQR)

 

Median (IQR)

 

Median (IQR)

 

Median (IQR)

MEHP

11.42 (19.01)**

 

104.75 (482.75)*

 

10.71 (19.80)

 

5.84 (10.79)

MEHHP

20.70 (21.37)***

 

196.72 (893.00)***

 

20.34 (36.20)

 

19.65 (16.99)***

MEHP + MEHHP

30.74 (58.29)***

 

301.47 (1375.64)***

 

36.88 (40.15)

 

25.01 (26.89)**

MEHHP/MEHP

2.44 (2.01)

 

3.50 (2.78)

 

1.93 (7.89)

 

2.62 (2.26)

Urinary metabolites (µg/g creatinine)

P-valuea

 

P-valueb

    

MEHP

< 0.001

 

< 0.001

    

MEHHP

< 0.001

 

< 0.001

    

MEHP + MEHHP

< 0.001

 

< 0.001

    

MEHHP/MEHP

0.097

 

0.563

    
  1. a Tested by Mann–Whitney U test
  2. b Tested by Kruskal–Wallis H test and Bonferroni correction
  3. * P < 0.05; ** P < 0.01; *** P < 0.001