Table 1 Summary of Neuraminidase inhibitors (NAIs)

Zanamivir

> 500 μM

(7.8 ± 2.0) μM

(4.0 ± 0.6) μM

(47 ± 6) μM

[48, 49]

Oseltamivir

> 500 μM

> 500 μM

> 500 μM

> 500 μM

Peramivir

> 500 μM

(70 ± 7) mM

> 500 μM

> 500 μM

2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA)

(49 ± 8) μM

(37 ± 6) μM

(7.7 ± 0.8) μM

(8.3 ± 1.0) μM

[50]

Neu5AcN32en

(24 ± 2) μM

(22 ± 3) μM

(4.4 ± 0.9) μM

(5.8 ± 0.8) μM

C9-butyl-amide-2-deoxy-2,3-dehydro-N-acetylneuraminic acid (C9-BA-DANA)

(3.4 ± 0.2) μM

> 500 μM

(110 ± 40) μM

(220 ± 50) μM

C9-biphenyltriazolyl DANA(C9-4BPT-DANA)

> 500 μM

(32 ± 5) μM

(0.7 ± 0.1) μM

(0.52 ± 0.1) μM

[51]

C9-4-hydroxymethyltriazolyl DANA(C9-4HMT-DANA)

(620 ± 10) μM

(240 ± 20) μM

(19.7 ± 2.3) μM

(60 ± 20) μM

[52]