Table 4 Specific correlation coefficient and p-values of the significant correlations between epithelial injury markers, histological evaluation, and clinical data in ARDS cases

Elafin

pO₂

-0.376

0.013

pCO₂

0.607

< 0.0001

HCO₃

0.509

< 0.0001

SO₂

-0,344

0.024

FO₂Hb

-0.398

0.027

FMetHb

0.402

0.028

FiO₂

0.360

0.014

PaO₂/FiO₂ ratio

-0.414

0.004

% Normal lung tissue

-0.295

0.046

% Bronchopneumonia

0.320

0.03

Hyaline membrane score

0.342

0.02

Oedema score

-0.298

0.044

RAGE

FCO₂Hb

0.395

0.025

PaO₂/FiO₂ ratio

-0.298

0.045

MV duration

-0.354

0.015

Haemorrhage score

0.318

0.029

Hyaline membrane score

0.318

0.029

% Normal lung tissue

pCO2

-0.457

0.002

HCO3

-0.544

< 0.0001

Base excess

-0.483

0.001

% Exudative DAD

FO2Hb

0.413

0.019

FHHb

-0.447

0.010

% Fibroproliferative DAD

pCO₂

0.324

0.032

HCO₃

0.382

0.010

Base excess

0.346

0.021

FHHb

0.378

0.033

FO₂Hb

-0.362

0.042

SOFA score

-0.326

0.034

Septal thickening score

Platelets

0.330

0.025

pCO₂

0.362

0.016

HCO₃

0.428

0.004

Base excess

0.383

0.010

FCO₂Hb

0.403

0.022

Oedema score

Platelets

-0.310

0.036

pCO₂

0.420

0.004

HCO₃

0.321

0.034

FiO₂

0.513

< 0.0001

PaO₂/FiO₂ ratio

-0.474

0.001

Inflammation score

pCO₂

0.350

0.02

Haemorrhage score

Lungs’ weight

0.429

0.003

Platelets

-0.346

0.018

Hyaline membrane score

pCO₂

0.347

0.021

HCO3

0.384

0.010

FMetHb

0.425

0.017

FiO₂

0.419

0.003

PaO₂/FiO₂ ratio

-0.394

0.006