Table 1 Demographic and clinical characteristics of Control, Septic and ARDS patients

Age in years, median (IQR)

62 (20)

59 (31)

55 (22)

0.079

BMI (Kg/m²), median (IQR)

24.1 (3.68)

25.7 (6.68)

24.3 (6.03)

0.310

Sex, n (%)

Male

12 (44.4%)

10 (33.3%)

24 (51.1%)

0.311

Female

15 (55.6%)

20 (66.7%)

23 (48.9%)

Self-declared Race, n (%)

White

20 (74.1%)

24 (80%)

32 (68.1%)

0.512

Afro-descendent

7 (25.9%)

6 (20%)

15 (31.9%)

Comorbidities, n (%)

SAH

20 (74.1%)

19 (63.3%)

20 (42.6%)

0.021

Cardiopathy

12 (46.2%)

8 (26.7%)

5 (10.6%)

0.003

Vascular disease

15 (57.7%)

5 (16.7%)

5 (10.6%)

< 0.0001

Diabetes mellitus

10 (37%)

11 (36.7%)

11 (23.4%)

0.335

Obesity

4 (14.8%)

7 (25.9%)

4 (10.3%)

0.229

Hepatic disease

4 (15.4%)

8 (26.7%)

9 (19.1%)

0.556

Neoplasia

2 (7.4%)

5 (16.7%)

14 (29.8%)

0.059

Alcoholism

2 (7.4%)

3 (10%)

6 (12.8%)

0.770

Chronic renal disease

0

4 (13.3%)

6 (15.8%)

0.056

Immunosuppression

0

3 (10%)

14 (29.8%)

0.041

Nervous system disease

0

3 (10%)

6 (15.8%)

0.173

Pulmonary Hypertension

0

3 (10%)

2 (4.3%)

0.251

HIV +

0

1 (3.3%)

3 (6.4%)

0.383

Period of hospitalization in days, median (IQR)

-

7.5 (24)

13 (14)

0.101

Mechanical ventilation duration in days, median (IQR)

-

1 (2)

3 (7)

< 0.0001

Period of ICU stay in days, median (IQR)

-

3.5 (7)

5 (10)

0.154

SOFA score, median (IQR)

-

15 (6)

15 (4)

0.961

Lungs weight in grams, median (IQR)

-

1026 (456)

1575 (756)

< 0.0001

Mechanical Ventilation, n (%)

-

25 (83.3%)

47 (100%)

0.031

FiO₂ (%), median (IQR)

-

100 (50)*

90 (50)

0.895

PEEP (cmH₂O), median (IQR)

-

8 (5)**

10 (6)

< 0.0001

PaO₂/FiO₂ ratio, median (IQR)

-

120.5 (136)***

95 (124)

0.218