Table 4 Early smoking impaired smoking cessation (after adjusting smoking index)
From: Early smoking lead to worse prognosis of COPD patients: a real world study
Variables | Early smoking (n = 104) | Late smoking (n = 104) | P-value |
|---|---|---|---|
Age, years | 68(61, 71) | 69(65,73) | 0.035 |
Male, % | 99 | 98.1 | 0.561 |
BMI, kg/m2 | 22.08(19.36,24.15) | 21.21(18.70,24.50) | 0.451 |
Smoking index ,packets/year | 40(33,60) | 40(33,60) | 0.999 |
Duration of smoking cessation, years | 9(3,13) | 10(3, 19) | 0.787 |
Spirometry(post-bronchodilation) | Â | Â | Â |
FEV1% predicted | 26(19.9,37) | 31.1(21,42.3) | 0.013 |
FEV1/FVC, % | 34.1(27.3,42.2) | 38(30,46.4) | 0.010 |
mMRC | 3(2,4) | 3(2,4) | 0.212 |
CAT | 23(16,27) | 28.5(25,34) | 0.252 |
Frequency of AEs in the last 12 months, times | 1(1,3) | 2(1,3) | 0.011 |
Frequency of admission for AECOPD in the last 12 months, times | 1(1,2) | 2(1,3) | 0.087 |
Laboratory investigations on admission | Â | Â | Â |
WBC count, x 109/L | 7.51(6.3,10.4) | 7.18(5.89,9.58) | 0.428 |
Neutrophil count, x 109/L | 5.31(4.25,8.36) | 5.52(4.02,7.46) | 0.098 |
Eosinophil count, x 109/L | 0.14(0.06,0.24) | 0.11(0.03,0.23) | 0.046 |
CRP, mg/l | 13(3.92,32.5) | 9.77(3.89,21.65) | 0.861 |
PCT, mg/l | 0.08(0.05, 0.14) | 0.08(0.05, 0.15) | 0.957 |
BNP, pg/ml | 120(50, 490) | 117(50, 555) | 0.685 |
PaCO2, mm/Hg | 50(43,63) | 50(43,62.8) | 0.638 |
PaO2, mm/Hg | 71(57,85) | 65(53,79) | 0.351 |
SaO2, % | 924(88,96) | 92 (87,96) | 0.542 |
ICS therapy during stable stage, % | 75 | 75 | 1 |
Triple therapy during stable stage, % | 30.8 | 24 | 0.277 |