Table 3 Comparison of clinical and 18FDG PET/CT characteristics among groups with different immune status, extent of lesion involvement and severity of NTM-PD
Characteristics | Immune status | Extent of lesion involvement | Severity of NTM-PD | ||||||
|---|---|---|---|---|---|---|---|---|---|
Immunocompromised | Immunocompetent | P | Localized | Disseminated | P | Severe | Non-severe | P | |
White cell count(× 109/L ) | 6.2 ± 4.3 | 10.1 ± 4.8 | 0.062 | 8.4 ± 4.1 | 8.6 ± 5.3 | 0.882 | 9.4 ± 5.6 | 7.4 ± 3.5 | 0.354 |
Neutrophilic granulocyte count (× 109/L ) | 4.2 ± 3.8 | 7.9 ± 4.9 | 0.068 | 5.7 ± 4.1 | 6.8 ± 5.1 | 0.642 | 7.2 ± 5.6 | 5.3 ± 2.8 | 0.378 |
lymphocyte count(× 109/L ) | 1.3 ± 1.2 | 1.4 ± 0.9 | 0.807 | 1.5 ± 1.4 | 1.3 ± 0.9 | 0.620 | 1.5 ± 1.2 | 1.1 ± 0.5 | 0.357 |
Red blood cell count(× 109/L ) | 3.5 ± 1.0 | 3.9 ± 0.7 | 0.184 | 3.9 ± 0.8 | 3.7 ± 0.8 | 0.685 | 3.7 ± 1.0 | 3.8 ± 0.5 | 0.945 |
Hemoglobin (g/dl) | 102.7 ± 32.3 | 112.7 ± 22.7 | 0.386 | 117.7 ± 25.2 | 104.9 ± 7.1 | 0.301 | 107.0 ± 30.4 | 111.7 ± 20.9 | 0.692 |
Platelet count (× 109/L ) | 240.0 ± 104.7 | 284.7 ± 126.3 | 0.386 | 225.4 ± 115.6 | 285.4 ± 117.9 | 0.272 | 314.0 ± 119.3 | 194.3 ± 73.1 | 0.003* |
C-reactive protein (mg/L) | 37.2 ± 36.1 | 64.3 ± 64.8 | 0.271 | 19.0 ± 10.1 | 64.9 ± 60.4 | 0.066 | 56.3 ± 55.1 | 42.5 ± 56.7 | 0.569 |
Erythrocyte sedimentation rate (mm/H) | 46.7 ± 33.6 | 43.5 ± 35.8 | 0.879 | 27.6 ± 15.3 | 36.6 ± 34.9 | 0.220 | 40.7 ± 38.7 | 10.6 ± 16.2 | 0.040 |
The percentage of total T lymphocyte (%) | 766.0 ± 726.7 | 1032.2 ± 444.2 | 0.494 | 60.9 ± 28.6 | 63.8 ± 27.9 | 0.880 | 69.6 ± 23.3 | 51.6 ± 31.8 | 0.305 |
IL-6 (pg/ml) | 35.6 ± 57.5 | 23.6 ± 44.7 | 0.579 | 36.3 ± 65.8 | 24.7 ± 42.1 | 0.615 | 39.9 ± 60.8 | 10.2 ± 7.1 | 0.163 |
TNF-α (pg/ml) | 11.8 ± 24.2 | 3.0 ± 2.1 | 0.127 | 10.6 ± 2.6 | 21.8 ± 2.1 | 0.221 | 21.1 ± 2.5 | 9.4 ± 3.1 | 0.341 |
Lactate dehydrogenase (U/L) | 218.8 ± 52.6 | 196.4 ± 66.3 | 0.404 | 214.9 ± 55.9 | 200.0 ± 64.5 | 0.626 | 217.6 ± 68.4 | 185.9 ± 44.3 | 0.233 |
SUVI−lung | 5.5 ± 3.9 | 7.2 ± 3.9 | 0.338 | 5.15 ± 3.55 | 6.7 ± 4.3 | 0.437 | 7.7 ± 4.3 | 4.3 ± 2.7 | 0.036* |
SUVE−Lung | 5.2 ± 2.8 | 6.9 ± 7.5 | 0.606 | NA# | NA | NA | 8.5 ± 7.4 | 4.5 ± 2.1 | 0.214 |
SUVTop | 5.2 ± 2.5 | 10.0 ± 6.4 | 0.038* | 5.6 ± 3.6 | 9.3 ± 6.1 | 0.153 | 9.0 ± 3.7 | 7.5 ± 7.1 | 0.559 |
SURLiver | 2.7 ± 1.4 | 4.3 ± 0.2.5 | 0.095 | 1.9 ± 1.1 | 3.8 ± 1.6 | 0.016* | 3.4 ± 1.2 | 2.8 ± 2.3 | 0.464 |
SURBlood | 4.7 ± 2.9 | 6.6 ± 4.3 | 0.258 | 2.7 ± 1.8 | 5.5 ± 2.6 | 0.026* | 5.3 ± 2.1 | 4.3 ± 3.3 | 0.410 |
SUVLiver | 2.6 ± 0.6 | 2.7 ± 0.7 | 0.825 | 2.7 ± 0.4 | 2.6 ± 0.7 | 0.762 | 2.7 ± 0.6 | 2.6 ± 0.6 | 0.586 |
SUVMarrow | 3.6 ± 1.6 | 3.7 ± 2.3 | 0.896 | 3.0 ± 0.08 | 3.9 ± 2.3 | 0.320 | 4.4 ± 2.0 | 2.4 ± 0.8 | 0.027* |
SUVSpleen | 2.7 ± 1.4 | 2.4 ± 0.4 | 0.444 | 2.0 ± 1.0 | 2.4 ± 1.3 | 0.489 | 2.5 ± 1.3 | 1.8 ± 0.7 | 0.131 |
MLV(cm3) | 56.4 ± 50.2 | 172.6 ± 261.9 | 0.206 | 35.6 ± 59.0 | 160.1 ± 245.0 | 0.204 | 116.2 ± 135.9 | 127.7 ± 271.5 | 0.900 |
TLG(ml*SUV) | 237.1 ± 256.8 | 748.3 ± 1230.9 | 0.236 | 119.7 ± 210.9 | 705.1 ± 1149.9 | 0.201 | 465.9 ± 559.1 | 582.9 ± 1299.1 | 0.785 |