Table 1 Demographics and clinical characteristics of patients with NTM infection
No. | Gender | Age | Bacterial species | Risk factor | Clinical symptoms | Diagnosis | Involved sites | Anti-NTM Pre-PET scan | SUVTop | MLV | TLG | PET/CT findings |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | M | 38 | M. abscessus | COPD | Fever, cough | mNGS (BALF) | Bilateral lungs | None | 11.3 | 161.3 | 578.8 | Pulmonitis |
2 | M | 58 | M. intracellulare | COPD | Ostealgia | Culture (Pus) | Right lung, multiple bones | None | 14.8 | 438.8 | 1802.5 | MM |
3 | M | 71 | M. intracellulare | Pulmonary TB history | Fatigue, cough | TB-DNA-PCR (Sputum) | Bilateral lungs, lymph nodes, adrenals | None | 11.8 | 972.6 | 4628.6 | Pulmonitis |
4 | M | 84 | M. intracellulare | COPD | Cough | Culture (Blood) | Bilateral lungs, lymph nodes | Oral ofl 1weeks | 7.5 | 42.6 | 148.7 | Pulmonitis |
5 | M | 29 | M. abscessus | AIDS | Fever | Culture (lymph node) | Bilateral lungs, lymph nodes | Oral Azi + Eth + Rif 3months | 6.6 | 48.2 | 128.4 | Lymphadenoma |
6 | M | 79 | M. intracellulare | COPD | Chest tightness | mNGS (BALF) | Left lung, lymph nodes | None | 4.1 | 27.3 | 79.7 | Pulmonitis |
7 | M | 50 | M. chimaera | Chemotherapy of lymphoma | None | mNGS (BALF) | Bilateral lungs | None | 2.4 | 0 | 0 | Pulmonitis |
8 | M | 61 | M. intracellulare | Splenectomy | Ostealgia | mNGS (bone surgery) | Multiple bones, lymph nodes | None | 6.0 | 58 | 200.3 | MM |
9 | M | 44 | M. kansasii | None | Ostealgia | mNGS (bone biopsy) | Bilateral lungs, lymph nodes, multiple bones, subcutaneous | None | 28.1 | 129.9 | 637.7 | Lung cancer and multiple metastases |
10 | F | 60 | M. abscessus | Chemotherapy of leukemia | None | TB-DNA-PCR (Sputum) | Bilateral lungs | Oral Azi + Eth + Rif 5 months | 1.2 | 0 | 0 | Pulmonitis |
11 | F | 14 | M. Avium | MonoMAc syndrome | Fever, cough | mNGS (lung puncture) | Bilateral lungs, lymph nodes | None | 5.1 | 70.9 | 244.1 | Pulmonitis |
12 | M | 63 | M. intracellulare | History of lung cancer. | Ostealgia | mNGS (bone biopsy) | Bilateral lungs, lymph nodes, multiple bones | None | 7.9 | 137.6 | 539.1 | Bone metastases |
13 | M | 19 | M. Avium | Hepatitis B cirrhosis | Fever | TB-DNA-PCR (Sputum) | Right lung, lymph nodes | Oral Eth + Rif 1 weeks | 5.5 | 60.3 | 211.2 | Pulmonitis |
14 | M | 60 | M. paraintracellulare | Chemotherapy of lung cancer | cough | mNGS (BALF) | Bilateral lungs, left 7 rib | Oral Azi + Eth + Rif 2 months | 4.5 | 27.8 | 88.4 | Recurrence of lung cancer |
15 | F | 70 | M. intracellulare | None | Fever, ostealgia | mNGS (lung puncture) | Left lung, multiple bones | None | 13.8 | 31.7 | 221.7 | Lung cancer and metastases |
16 | F | 60 | M. intracellulare | Splenectomy | Fever, cough | Culture (Sputum) | Bilateral lungs, lymph nodes | None | 13.0 | 309.8 | 1283.5 | Pulmonitis |
17 | M | 78 | M. intracellulare + M. kansasii | COPD | Weight loss | mNGS (BALF) | Left lung | Oral Azi + Eth + Rif 2 months | 8.3 | 0.7 | 2.6 | Pulmonitis |
18 | M | 73 | M. Avium | None | Fever, cough | mNGS (lung puncture) | Bilateral lungs, lymph nodes | None | 5.8 | 44.9 | 137.9 | Lung cancer and metastases |
19 | M | 61 | M. intracellulare | Chemotherapy of Lung MALToma | Fatigue | mNGS (BALF) | Bilateral lungs, lymph nodes | None | 5.2 | 135.1 | 666.1 | Recurrence of lung maltoma |
20 | M | 27 | M. Avium | AIDS | Fever | Culture (Blood) | Bilateral lungs, lymph nodes, spleen | Oral Cla + Mox + Eth + Rif 3 months | 6.4 | 21.5 | 176.2 | Pulmonitis |
21 | M | 66 | M. intracellulare | COPD | Cough | Culture (Sputum) | Bilateral lungs | None | 3.4 | 1.2 | 3.3 | IIP |
22 | M | 61 | M. abscessus | Chemotherapy of pancreatic cancer | Fever | mNGS (BALF) | Bilateral lungs | None | 6.3 | 38 | 124.8 | Pulmonitis |
23 | M | 55 | M. intracellulare | Chemotherapy of MDS | Fever | mNGS (BALF) | Bilateral lungs, lymph nodes | None | 9.9 | 52.4 | 216 | Invasion of tumor |