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Table 1 Definition of terms used

From: Respiratory entrainment related reverse triggering in mechanically ventilated children

Term Definition

Coefficient of variation

Statistical measure used to assess the relative variability of a dataset expressed as a percentage.

CoV = (standard deviation/mean) * 100.

Double triggering

Two consecutive ventilator cycles separated by a short expiratory time, i.e., half of the inspiratory time or less.

Entrained reverse triggering

Breathing effort after the start of a ventilator cycle in a regular pattern (four consecutive reverse triggered breaths). Pattern occurring in a 1:1, 1:2 or in 1:3 ratio. During entrainment the patient is cycling between patient triggered and reverse triggered breaths. Breathing pattern is showing low variability (i.e. coefficient of variation < 15%).

Non-entrained reverse triggering

Breathing effort after the start of a time triggered mandatory breath occurring as a single event.

Patient-triggered breath

Patient effort (increase in electrical activity of the diaphragm/negative deflection in the oesophageal pressure tracing) followed by a ventilator pressurization.

Phase-angle

Calculation to describe the time duration or delay between a patient effort and the initiation of the ventilator pressurization. A phase angle of 0° means that the patient effort starts at the same time as the initiation of the ventilator pressurization. A phase angle of 180° means that the patient’s effort starts halfway between the start of two mandatory breaths.

Phase angle = (start patient effort – start ventilator pressurization/breathing cycle) * 360°.

Respiratory entrainment

Form of neuromechanical coupling in which the subject’s breathing frequency matches an external stimulus creating a fixed patient respiratory rhythm with less variability (i.e. coefficient of variation < 15%).

Reverse triggering

Patient effort generated after a time triggered mandatory breath.

TTOTMECH

Duration of the ventilator breath. Time (sec) period between the start of a time cycled mandatory breath until the start of the consecutive time cycled mandatory breath

TTOTNEU

Duration of a patient triggered ventilator cycle. Time (sec) between the start of a patient effort (based on dEMG signal or oesophageal pressure) until the start of the consecutive patient effort

Time triggered mandatory breath

Ventilator pressurization without any signs of a patient effort.