Fig. 2
From: Bhlhe40 deficiency attenuates LPS-induced acute lung injury through preventing macrophage pyroptosis
Bhlhe40 deficiency increases resistance to LPS-induced ALI in mice. (A) Representative Hematoxylin-eosin staining (H&E) of lung tissues in mice after LPS induction. Scale bar = 100 μm. (B) Lung injury score based on H&E staining. (C) Total number of cells counted in the BALF of mice. (D) Total protein concentration in the BALF of mice. (E) IL-1β levels in BALF of mice. (F) IL-10 levels in BALF of mice. (G-K) Relative mRNA levels of inflammatory cytokines (Il-6, Tnf-α, Ifn-γ, Mcp-1, Cxcl10) in the lungs of mice after LPS induction. n = 6. Data are shown as the mean ± SEM. Statistical analysis was performed by two-way ANOVA followed by Bonferroni’s multiple comparisons test. **p < 0.01, ***p < 0.001