Table 3 MR results in urinary metabolites from cohort 1
Outcome | Exposure | Method | SNPs | OR | 95% CI | P value | Heterogeneity test Q (P value) | MR-Egger pleiotropy test Intercept (P value) |
|---|---|---|---|---|---|---|---|---|
Allergic Rhinitis | Histidine | IVW | 2 | 0.555 | 0.359−0.856 | 0.008 | 0.399 | NA |
|  | Alanine | Wald ratio | 1 | 0.307 | 0.108−0.875 | 0.027 | NA | NA |
|  | Threonine | Wald ratio | 1 | 0.2634 | 0.081−0.861 | 0.027 | NA | NA |
|  | Lysine | Wald ratio | 1 | 1.272 | 1.003−1.612 | 0.047 | NA | NA |
|  | Maleate | Wald ratio | 1 | 1.400 | 1.004−1.951 | 0.047 | NA | NA |
Asthma | Histidine | IVW | 2 | 0.759 | 0.597−0.964 | 0.024 | 0.767 | NA |
|  | Glycolate | Wald ratio | 1 | 1.852 | 1.082−3.170 | 0.025 | NA | NA |
|  | Tyrosine | IVW | 3 | 0.742 | 0.567−0.972 | 0.030 | 0.559 | 0.686 |
|  | O.Phosphocholine | Wald ratio | 1 | 0.516 | 0.281−0.947 | 0.033 | NA | NA |