Fig. 8

Deciphering the cell interactions between macrophage and fibroblast subpopulations associated with airway inflammation and remodeling. The top30 ligand activity and the expression level of these ligands in sender cells (A) int macrophage and alv macrophage; and (B) Col14a1 + Fib and Col14a1 + Fib/Myofib) to their respective receiver cells were presented. Log2FoldChange of these ligand expression values, comparing AS to NC group, and the predicted target genes in receiver cells were identified by NicheNet analysis