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Fig. 6 | Respiratory Research

Fig. 6

From: Upregulated microRNA-125b-5p in patients with asthma-COPD overlap mediates oxidative stress and late apoptosis via targeting IL6R/TRIAP1 signaling

Fig. 6

The effect of CSE+OVA and miR-125b-5p siRNA in mediating oxidative stress and late apoptosis. Percentage of reactive oxygen species (ROS)-producing cells (n = 3) (A) and late apoptotic cells (n = 3) (B) in the THP-1 cell culture model. Percentage of ROS-producing cells (n = 3) (C) and late apoptotic cells (n = 3) (D) in the NHBE cell culture model. In both the THP-1 and NHBE cell culture models, the cells were stimulated with CSE and OVA before and after transfection with 10 µM miR-125b-5p siRNA. *p < 0.05; **p < 0.001

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