Fig. 4

Heterogeneity of CD8⁺ T cell subpopulations among ARDS patients and KTRs with ARDS. A, B Composition and single-cell maps of CD8⁺ T cells in patients with ARDS. C The dynamic changes of CD8⁺ T cell subpopulations in patients with ARDS. D Single-cell maps reveal marker gene expression in CD8⁺ T cell subpopulations. E Identification of CD8⁺ T cell subpopulations based on the expression of specific biomarker genes associated with each cell subpopulation. F Expression of marker genes in CD8⁺ T cell subpopulations. G Bubble chart illustrating the signaling pathways associated with CD8⁺ T cell subpopulations. H Single-cell trajectory analysis of CD8⁺ T cell subpopulations. I Motif module heatmap representing the CD8⁺ T cell subpopulations. J Transcription factors present in CD8⁺ T cell subpopulations. K Transcription factor activities in Te_CCL5_GZMH and Te_GZMB_XAF1