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Table 1 Baseline information of enrolled patients before or after propensity score matching

From: Blood glucose and lipids are associated with sarcoidosis: findings from observational and mendelian randomization studies

 

Before matching

After matching

Sarcoidosis

(n = 162)

Non-sarcoidosis

(n = 594)

P value

Sarcoidosis

(n = 160)

Non-sarcoidosis

(n = 160)

P value

Demographic characteristics

 Sex

  

< 0.001

  

> 0.999

  Male

53 (32.7%)

311 (52.4%)

 

53 (33.1%)

53 (33.1%)

 

  Female

109 (67.3%)

283 (47.6%)

 

107 (66.9%)

107 (66.9%)

 

 Age (years)

48.79 (11.79)

46.05 (13.03)

0.016

48.54 (11.65)

49.08 (11.73)

0.681

 Weight (kg)

61.54 (11.00)

64.18 (11.32)

0.008

61.57 (11.06)

61.95 (10.26)

0.752

 Smoking history

19 (11.7%)

133 (22.4%)

0.003

19 (11.9%)

22 (13.8%)

0.738

Comorbidities

 Hypertension

13 (8.0%)

97 (16.3%)

0.008

13 (8.1%)

17 (10.6%)

0.566

 Coronary disease

6 (3.7%)

31 (5.2%)

0.540

6 (3.8%)

6 (3.8%)

> 0.999

 Fatty liver

14 (8.6%)

42 (7.1%)

0.500

12 (7.5%)

13 (8.1%)

> 0.999

 Diabetes

18 (11.1%)

66 (11.1%)

> 0.999

18 (11.3%)

22 (13.8%)

0.613

 Uveitis

4 (2.5%)

1 (0.2%)

0.009

4 (2.5%)

0 (0.0%)

0.123

Blood glucose and lipid traits

 Fasting glucose (mmol/L)

5.87 (5.02–6.65)

5.40 (4.90-6.00)

< 0.001

5.87 (5.03–6.66)

5.40 (4.85-6.00)

< 0.001

 HDLC (mmol/L)

1.09 (0.34)

1.21 (0.34)

< 0.001

1.07 (0.89–1.21)

1.24 (1.03–1.50)

< 0.001

 LDLC (mmol/L)

2.82 (2.33–3.14)

2.41 (1.90–2.88)

< 0.001

2.82 (2.32–3.15)

2.46 (1.99–2.83)

< 0.001

 TC (mmol/L)

4.65 (4.10–5.43)

3.92 (3.36–4.46)

< 0.001

4.65 (4.09–5.42)

4.02 (3.49–4.56)

< 0.001

 TG (mmol/L)

1.65 (1.16–2.39)

1.16 (0.77–1.80)

< 0.001

1.65 (1.16–2.40)

1.11 (0.80–1.86)

< 0.001

Other blood traits

 Blood potassium (mmol/L)

3.99 (0.29)

4.14 (0.28)

< 0.001

3.99 (0.29)

4.14 (0.27)

< 0.001

 Blood calcium (mmol/L)

2.34 (0.13)

2.30 (0.10)

0.001

2.33 (2.26–2.40)

2.30 (2.25–2.37)

0.058

 ALT (U/L)

19.00 (14.00-24.20)

17.07 (12.00-24.76)

0.075

19.21 (14.00-24.52)

16.00 (12.10-24.76)

0.067

 AST (U/L)

20.91 (18.00-23.50)

19.00 (16.00–24.00)

0.004

20.91 (18.00-23.75)

19.00 (16.25-24.00)

0.027

 GGT (U/L)

28.33 (19.00–49.00)

21.35 (14.83–32.50)

< 0.001

28.33 (19.00-50.50)

20.73 (14.31–28.78)

< 0.001

 ALP (U/L)

73.00 (61.00-92.67)

69.00 (58.25-82.00)

0.010

73.14 (61.00-92.67)

69.63 (58.00-83.10)

0.083

 ALB (g/L)

42.71 (3.64)

43.37 (3.73)

0.045

42.67 (3.65)

43.60 (3.24)

0.016

 Globulin (g/L)

30.58 (5.10)

27.64 (3.83)

< 0.001

29.95 (27.35–33.27)

27.62 (25.33–30.16)

< 0.001

 TBil (umol/L)

9.18 (7.10–12.40)

8.69 (6.40-11.73)

0.046

9.23 (7.10–12.40)

8.28 (6.60–11.00)

0.034

 UA (umol/L)

310.00

(257.00-396.10)

306.40

(258.73-371.86)

0.254

310.00

(256.60-396.35)

287.00

(236.41-341.88)

0.001

 Urea (mmol/L)

5.39 (4.30–6.65)

5.10 (4.33–6.05)

0.095

5.34 (4.30–6.68)

5.13 (4.39–6.07)

0.283

 Creatinine (umol/L)

68.00 (57.00–79.00)

71.00 (58.00-83.29)

0.221

68.00 (57.00-79.50)

64.00 (55.13–76.32)

0.085

 RBC (10^12/L)

4.52 (0.52)

4.47 (0.58)

0.305

4.53 (0.52)

4.43 (0.58)

0.127

 Hb (g/L)

132.64 (15.12)

134.12 (19.20)

0.300

132.75 (15.17)

130.68 (18.54)

0.274

 PLT (10^9/L)

223.38

(190.00-272.86)

214.80

(182.00-252.75)

0.032

223.38

(190.25-273.43)

223.75

(181.08-250.25)

0.149

 WBC (10^9/L)

5.70 (4.47–6.62)

6.19 (5.12–7.31)

< 0.001

5.68 (4.44–6.61)

5.89 (5.01–7.06)

0.052

  1. N (%), mean (SD), median (25-75%). HDLC, high density lipoprotein cholesterol. LDLC, low density lipoprotein cholesterol. TC, total cholesterol. TG, total triglyceride. ALT, alanine amino transferase. AST, aspartate amino transferase. GGT, gamma glutamyl transferase. ALP, alkaline phosphatase. ALB, albumin. TBil, total bilirubin. UA, uric acid. RBC, red blood cell. Hb, hemoglobin. PLT, platelet. WBC, white blood cell