IR808@MnO nano-near infrared fluorescent dye’s diagnostic value for malignant pleural effusion

Respiratory Research

Table 2 Analysis of predictive efficacy for different indicators

Indicator	Cutoff	Sensitivity (%)	Specificity (%)	J	AUC	95%Cl	P
Fluorescence quantification	25,145,000	79.49	74.36	0.5385	0.7617	0.6517–0.8716	< 0.0001
Fluorescence imaging	–	82.05	69.23	0.5128	0.7564	0.6457–0.8671	< 0.0001
Pleural fluid cytological	–	100	30.77	0.3077	0.6538	0.5312–0.7765	0.0194

Pleural fluid cytological: traditional pleural effusion cytology examination and diagnosis; Fluorescence imaging: the fluorescence absorption of IR808@MnO in malignant cells; Fluorescence quantification: the fluorescence intensity of IR808@MnO

ISSN: 1465-993X