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Table 1 Comparison Table of Baseline and Observational Indicators for Dual Patient Groups

From: IR808@MnO nano-near infrared fluorescent dye’s diagnostic value for malignant pleural effusion

Variant

BPE (n = 39)

MPE (n = 39)

χ2/Z

P

Age (years)

73 (64, 83)

61 (54, 80)

− 1.530

0.126

Sex

  

1.338

0.355

 Male

26 (66.7)

21 (53.8)

  

 Female

13 (33.3)

18 (46.2)

  

Chronic disease history

  

2.519

0.173

 Yes

15 (38.5)

22 (56.4)

  

 No

24 (61.5)

17 (43.6)

  

Pleural fluid cytological

  

14.182

< 0.001

 Positive

0 (0)

12 (30.8)

  

 Negative

39 (100)

27 (69.2)

  

Fluorescence imaging

  

20.856

< 0.001

 Positive

7 (17.9)

27 (69.2)

  

 Negative

32 (82.1)

12 (30.8)

  

Fluorescence quantification (107)

5.13 (2.30, 1.50)

1.59 (1.14, 2.42)

− 3.978

< 0.001

  1. BPE: Benign Pleural Effusion Group; MPE: Malignant Pleural Effusion Group; Chronic medical history mainly includes chronic diseases such as high blood pressure, diabetes, heart disease, cerebral infarction, etc. Pleural fluid cytological: traditional pleural effusion cytology examination and diagnosis; Fluorescence imaging: the fluorescence absorption of IR808@MnO in malignant cells; Fluorescence quantification: the fluorescence intensity of IR808@MnO