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Table 4 Effects of DNA measures on the rate of exacerbations by GOLD stage†

From: Cell-free DNA levels associate with COPD exacerbations and mortality

 

GOLD I/II

n = 933

GOLD III

n = 886

GOLD IV

n = 286

cf-mtDNA copy number (natural log)

1.06 (0.011)

1.05 (0.012)

0.99 (0.75)

cf-nDNA copy number (natural log)

1.01 (0.84)

0.95 (0.19)

0.98 (0.66)

  1. Definition of abbreviations: GOLD = Global Initiative for Obstructive Lung Disease; cf-mtDNA = cell-free mitochondrial DNA; cf-nDNA = cell-free nuclear DNA
  2. †Cells represent the ratio of the mean (P value) from a gamma regression. All analyses are adjusted for age, body mass index, and sex
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Respiratory Research

ISSN: 1465-993X

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