Cell-free DNA levels associate with COPD exacerbations and mortality

Respiratory Research

Table 2 Baseline cell-free DNA Levels by GOLD Stage

	GOLD I/II n = 944	GOLD III n = 893	GOLD IV n = 290	P value^A
cf-mtDNA (copies/µL), median (IQR)	1,220 (334-3,639)	911 (219-3,151)	901 (244-2,689)	0.017
cf-nDNA (copies/µL), median (IQR)	0.5 (0.3–0.8)	0.5 (0.3–0.9)	0.7 (0.4–1.3)	< 0.001

Definition of abbreviations: GOLD = Global Initiative for Obstructive Lung Disease; cf-mtDNA = cell-free mitochondrial DNA; cf-nDNA = cell-free nuclear DNA. ^AFrom t-test for quantitative data and Fisher’s exact test for categorical data

ISSN: 1465-993X