Fig. 2
From: Unraveling EGFR-TKI resistance in lung cancer with high PD-L1 or TMB in EGFR-sensitive mutations
Mutation analysis in the high and nonhigh PD-L1 expression groups. (A) Immunohistochemical image of lung cancer patients with high expression of PD-L1 (TPS ≥ 50%) and nonhigh expression (TPS < 50%); (B) Overview of mutation profiles in patients with high expression of PD-L1; (C) Overview of mutation profiles in patients with nonhigh expression of PD-L1; (D) Comutation analysis in patients with high expression of PD-L1; (E) Comutation analysis in patients with nonhigh expression of PD-L1; (F) Forest plot of comparing mutations between patients with high expression and nonhigh expression of PD-L1; (G) Co-bar plot of differentially mutated genes in patients with high expression and nonhigh expression of PD-L1. “*”, “**”, and “***” indicate P < 0.05, P < 0.01, and P < 0.001