Patient groups | Screening cohort (metabolomic analysis) | Validation cohort (quantitative analysis) | Combined cohort (quantitative analyses) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
[n] | Ages | BMI | Sex [M/F] | [n] | Ages | BMI | Sex [M/F] | [n] | Ages | BMI | Sex [M/F] | |
All-DILD | 60 | 70 (66–74) | 21.9 (19.5–23.8) | 37/23 | 22 | 65 (58–71) | 22.1 (19.1–23.5) | 17/5 | 81 | 69 (63–73) | 21.9 (19.1–23.7) | 53/28 |
DAD/DAD-mixed | 20 | 68 (64–74) | 21.7 (19.9–22.9) | 17/3 | 3 | 69 (62–70) | 22.3 (21.8–22.6) | 3/0 | 22§ | 68 (62–72) | 21.7 (20.3–22.6) | 19/3 |
OP | 31 | 69 (66–74) | 22.0 (19.0–23.6) | 16/15 | 2 | 79 (76–82) | 21.5 (20.5–22.6) | 2/0 | 32§ | 70 (67–75) | 22.0 (19.0–23.6) | 18/14 |
NSIP | 9 | 73 (71–75) | 22.5 (20.8–25.3) | 4/5 | 16 | 63 (59–69) | 22.3 (17.9–24.0) | 12/4 | 26# | 69 (61–73) | 22.6 (20.1–24.3) | 16/10 |
Other | – | – | – | – | 1 | 50 | 20.8 | 0/1 | 1 | 50 | 20.8 | 0/1 |
DILD recovery | 34 | 69 (67–74) | 22.7 (20.2–24.8) | 22/12 | 17 | 62 (55–69) | 21.8 (18.2–23.8) | 12/5 | 53# | 69 (63–72) | 22.7 (19.4–24.1) | 35/18 |
DILD-tolerant | – | – | – | – | – | – | – | – | 20 | 70 (67–72) | 21.5 (20.2–23.5) | 12/8 |
Lung cancer | – | – | – | – | – | – | – | – | 45 | 72 (62–76) | 21.7 (19.8–25.2) | 31/14 |
BP | – | – | – | – | – | – | – | – | 14 | 66 (64–78) | 22.8 (19.3–25.0) | 11/3 |
NTM | – | – | – | – | – | – | – | – | 15 | 74 (71–76) | 18.4 (17.4–21.7) | 5/10 |
IIPs | – | – | – | – | – | – | – | – | 23 | 73 (62–76) | 23.3 (20.4–25.3) | 17/6 |
CTD | – | – | – | – | – | – | – | – | 20 | 68 (65–70) | 23.8 (21.7–26.0) | 8/12 |
COPD | – | – | – | – | – | – | – | – | 15 | 70 (65–76) | 21.1 (18.8–23.9) | 13/2 |
BA | – | – | – | – | – | – | – | – | 12 | 60 (51–72) | 24.5 (20.5–30.2) | 3/9 |
HC | – | – | – | – | – | – | – | – | 30 | 60 (58–62) | 20.6 (20.0–22.9) | 15/15 |