Fig. 3

Diagnostic potentials of KYN, QUNA, KYN/TRP ratio, and conventional DILD biomarkers. ROC curve analyses of serum levels of KYN and QUNA, KYN/TRP ratio, and levels of conventional ILD biomarkers (SP-D and KL-6) were performed between the groups using the quantitative data of all samples in the combined cohort. The ROC curves of all-DILD patients compared with DILD-tolerant A, DILD recovery B, IIPs C, or CTD D are shown. The values of AUROC are described in the parentheses of the labels for each tested biomarker. The AUROC values for other comparisons are summarized in Table 3