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Fig. 2 | Respiratory Research

Fig. 2

From: CD147 induces asthmatic airway remodeling and activation of circulating fibrocytes in a mouse model of asthma

Fig. 2

The effect of anti-CD147 in OVA-induced airway goblet cell metaplasia and collagen deposition in asthmatic mice

OVA-induced asthmatic mice were treated with anti-CD147 or Isotype antibody. Mice treated only with PBS were considered as the control. (A) Representative photographs of lung sections stained with PAS; bronchial goblet cells appear fuchsia. Magnification ×400, scale bar = 50 μm. (B) Scoring of PAS based on PAS staining (n = 6). (C) Representative photographs of lung sections stained with Masson trichrome, collagen fibers appear blue, muscle fibers and cytoplasm appear red, and the nuclei appear blue-black. Magnification ×400, scale bar = 50 μm. (D) Quantification of peribronchial collagen deposition based on Masson staining (n = 6). Data were presented as mean ± SD, and analyzed by one-way ANOVA with Bonferroni correction. *P < 0.05, vs. control; #P < 0.05, vs. OVA

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Respiratory Research

ISSN: 1465-993X

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