Table 2 Univariable and multivariable analyses with logistic regression models for variables associated with TBP in pleural effusion with ADA ≥ 40 IU/L

Age ≥ 65 years

1.04 (0.81–1.34)

Pleural effusion

 ADA, IU/L

  40 ≤ ADA < 70

Reference

Reference

  70 ≤ ADA < 150

6.28 (4.73–8.34)

3.11 (1.95–4.95)

  ADA ≥ 150

0.34 (0.17–0.69)

0.35 (0.14–0.90)

 Lymphocytes, %

  Lymphocytes < 35

Reference

Reference

  35 ≤ Lymphocytes < 70

19.38 (12.90–29.11)

6.67 (3.92–11.33)

  Lymphocytes ≥ 70

78.03 (49.06–124.11)

13.79 (7.74–24.56)

 Eosinophils < 10%

4.75 (1.68–13.44)

4.61 (1.16–18.36)

 pH < 7.2

0.26 (0.14–0.48)

 Glucose < 60 mg/dL

0.15 (0.11–0.21)

 Protein ≥ 2/3× serum ULN

1.72 (1.29–2.29)

 LD/ADA < 18

44.68 (29.70–67.22)

14.00 (8.51–23.03)

Serum

 WBC < 10,000/µL

10.51 (7.07–15.62)

3.41 (1.92–6.03)

 Platelets ≥ 150,000/µL

3.41 (2.29–5.09)

2.45 (1.34–4.46)

 Protein < serum LLN

3.90 (2.85–5.33)

 LD ≥ 2× serum ULN

0.75 (0.56–0.99)