Fig. 2From: High-dose vitamin D3 supplementation shows no beneficial effects on white blood cell counts, acute phase reactants, or frequency of respiratory infectionsScatterplots of inflammatory markers in the vitamin D3 group and placebo group after 150 days of treatment. Vitamin D3 group presented as red dots with red trend line and 95% confidence intervals for the regression lines. Placebo group presented as blue dots with a blue trend line and 95% confidence intervals for the regression lines, both as a function of serum 25(OH)D3 in a pooled linear regression model. (a) Leucocytes. (b) Neutrophils. (c) Eosinophils. (d) Lymphocytes. (e) Monocytes. (f) Orosomucoid. r-values: Pearson’s correlation coefficient. P-values: Pearson’s correlation with a two-tailed test of significance. * p < 0.05, ** p < 0.01, and *** p < 0.001. Regression p-values for leucocytes and monocytes were 0.016 and 0.013, respectively. Neutrophils and lymphocytes were borderline significant, 0.059 and 0.077, respectively. Regression p-values were calculated with Student’s t-test. Abbreviations: S-25(OH)D3, serum 25-hydroxyvitamin D3Back to article page