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Fig. 2 | Respiratory Research

Fig. 2

From: Assessing the protection elicited by virus-like particles expressing the RSV pre-fusion F and tandem repeated G proteins against RSV rA2 line19F infection in mice

Fig. 2

RSV-specific serum antibody responses and virus neutralization. Sera were collected from mice 4 weeks after each immunization. RSV-specific IgG (A) and IgA (B) antibody responses against FI-RSV antigens were measured by ELISA. Serum-mediated virus neutralization assay was performed using the sera acquired after the second immunization. Serially diluted sera were incubated with 50 pfu of RSV rA2-line19F virus (C). Virus neutralization at 1:500 (D) and 1:1,000 (E) serum dilutions were further evaluated. Data are presented as mean ± SD from experiments performed in triplicate (* p < 0.05, ** p < 0.01, *** p < 0.001)

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Respiratory Research

ISSN: 1465-993X

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